In recent years, as a kind of acyclic cross conjugated oligoolefins, dendralenes has attracted more and more attention due to its unique structure and application value
-component double cyclization and ring opening: Construction of benzo [e] [1,4] diazo-3-one reaction by breaking double C-O bond
Time of Update: 2019-10-16
Recently, the research group of Professor Wu Anxin of central China Normal University has made a new breakthrough in the new molecular design of 1,4-benzodiazepine skeleton (DOI: 10.1021/acs.orglett.9b02789).
nitrogen compounds by asymmetric hydrogenation of C = n bond catalyzed by cobalt
Time of Update: 2019-09-15
Lead chiral nitrogen-containing compounds are a class of dominant structural units, which are widely used in the synthesis of a variety of chiral pharmaceuticals, pesticides, catalysts and other functional molecules (Figure 1).
University, reported the first novel biomimetic ion transport channel based on the coordinated regulation of hydrogen bond and anion π interaction
Time of Update: 2019-08-15
It is a common physiological phenomenon that ions migrate across membrane by protein channels
Its existence not only maintains the normal homeostasis of cells, but also
on the carbon ring of indole by using chiral hydrogen bond catalysis
Time of Update: 2019-07-26
2019, 21, 5219-5224), a new type of asymmetric catalyst with high catalytic activity, was synthesized on indole carbon ring by using chiral hydrogen bond catalysis for the first time.
[quick news] on June 3, 2019, Dalian Institute of chemical industry, Chinese Academy of Sciences
Time of Update: 2019-06-03
Http://news.scienceet.cn/htmlnews/2019/6/427019.shtm the price of "life-saving medicine" for coronary heart disease has increased nearly 11 times.
Dong Shengyi and Zhao Wanxiang of Hunan University have made important progress in the research of supramolecular adhesion materials based on hydrogen bonding
Time of Update: 2019-06-01
Hydrogen bond driven self-assembly is a widely used method to synthesize supramolecular polymer materials
Many supramolecular polymers prepared by hydrogen bonding have
bond assisted reagent effect controlled rare 3-aminosugar β - glycosylation
Time of Update: 2019-05-31
Introduction 3,5-trans-3-amino-2,3,6-trioxypyranose (3,5-trans-3-amino sugar) is widely found in some antibiotics with good biological activity, and its connection mode is mainly β
Shaanxi Normal University has made important progress in the field of green selective silicon hydrogen bond oxidation
Time of Update: 2019-05-10
Oxidation is one of the most important reactions in organic chemistry
Selective oxidation can be used to synthesize organic chemical products, material molecules, drug
Li zhanting and Zhang Danwei of Fudan University have made important progress in the construction of supramolecular helix driven by hydrogen and halogen bonds
Time of Update: 2019-03-23
Recently, Li zhanting and Zhang Danwei, Department of chemistry, Fudan University, used the intermolecular n · · I halogen bond to "bond" the short aromatic amide folding body
Research team of Professor Li Hongxi and Professor Lang Jianping of Suzhou University: photoinduced reverse hydrogen atom transfer to construct C-S bond
Time of Update: 2019-01-04
The author: Xu Zeming benzothiazole compounds are widely found in natural products, drug molecules, organic materials and so on
Many synthetic methods of these compounds
Capture of highly active anions: supramolecular receptors based on hydrogen bonds
Time of Update: 2018-11-29
SCI.), the author studied the binding ability of anion receptor 1-tbu and 2-cf3 to HSE -.
Sun Baiwang and Luo Yanghui research team of Southeast University: dynamic 3D hydrogen bonded
Time of Update: 2018-10-23
First, the research team used the "isometric eutectic" strategy (Figure 1) to prepare the HOF material tcpp-1,3-dpp with one-dimensional porous band structure based on heme compound TCPP.
Science: let cobalt have rhodium properties - Asymmetric Hydrogenation of enamide catalyzed by cobalt
Time of Update: 2018-06-10
(source: Science) in order to verify the practicability of the zinc methanol method, the author carried out a hydrogenation reaction of up to 200g scale, and obtained levetiracetam (Fig. 4) with 97% separation yield and 98.2% ee value.
to realize the boron hydrogen bond functionalization of carboranemethylamine
Time of Update: 2018-04-17
Article author: Zhang Xiaolei recently, Dr
Zhang Xiaolei, School of pharmacy, Jiangnan University, and Professor Yan Hong, School of chemistry and chemical engineering
19F NMR study of intramolecular hydrogen bond of fluorine-containing compounds
Time of Update: 2017-12-18
The formation of intramolecular hydrogen bonds can affect many physical and chemical properties of compounds, such as pKa, boiling point, solubility, etc., which can significantly improve the membrane permeability and three-dimensional space pre organization of molecules.
and the world intellectual property headquarters (a series of reports in Europe 3)
Time of Update: 2017-07-03
Song Ruilin, executive chairman, introduced to Yi Xiaozhun, deputy director general, the current situation of China's pharmaceutical intellectual property protection, achievements in innovation and development of the pharmaceutical industry, and the recent pharmaceutical regulatory reform in China.
Hydrogen bond, I'm glad I didn't give up. Finally I see you
Time of Update: 2017-05-22
Combustible ice is a hydrogen bonded crystal formed by eight water molecules and one methane at low temperature and high pressure.