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How does clearing bad mitochondria affect stem cell division?
Time of Update: 2022-04-19
"I study a process called mitochondrial phagocytosis, which cleans up these damaged mitochondria," said Alicia Pickrell, assistant professor in Virginia Tech's College of Neuroscience.
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Cell Rep: Mitochondria efficiently adapt to changing metabolic conditions
Time of Update: 2022-03-07
The teams surrounding Rampelt and Pfanner have now demonstrated that MICOS and ATP synthase can communicate with each other, which is critical for healthy mitochondrial function .
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Researchers discover a new PARP-like enzyme in mitochondria
Time of Update: 2022-03-06
The new mitochondrial enzyme, called NEURL4, has activity similar to that of PARP1, a ribozyme that plays an important role in DNA damage repair and gene expression regulation .
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A new PARP-like enzyme discovered in mitochondria
Time of Update: 2022-03-04
To characterize the enzymatic activity of NEURL4, a team led by first and co-corresponding author Maria Dafne Cardamone, Ph.
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Hostility in cells takes over: pathogens hijack host mitochondria
Time of Update: 2022-01-21
Because the outer membrane of these organelles is the first point of contact with the pathogen, we looked at it more closely," Lena Penas, research group leader at the Max Planck Institute for the Biology of Aging, explains .
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bimodal small molecule imaging probe targeting myocardial mitochondria
Time of Update: 2022-01-09
(the membrane potential of cardiomyocyte mitochondria is also higher) . However, no studies have reported its application in cardiac imaging .
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Shanghai Institute of Medicine and others develop PET/fluorescence bimodal small molecule imaging probes targeting myocardial mitochondria
Time of Update: 2022-01-09
Based on the unique fluorescence properties of lipophilic cation F16 and the mitochondrial targeting mechanism, this study designed and synthesized a novel dual-modal probe 5MEF, which can be used for myocardial PET imaging and fluorescence imaging (Figure 1) .
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the bottom and stole the mitochondria of immune cells to achieve immune escape.
Time of Update: 2021-12-04
>"The Thirty-Six Strategies" is a collection of ancient Chinese war wisdom. The ancients even distilled these war strategies into short proverbs, such as: concealing the sky
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Refresh cognition... Cancer cells will actively attack immune cells and steal each other’s mitochondria
Time of Update: 2021-12-01
The new study found that when cancer cells and immune cells coexist, the former will stretch out extremely tiny "tentacles" to steal substances necessary for survival from neighbors .
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"Circulation" "immortal protein" ignites cell mitochondria
Time of Update: 2021-11-15
pressure cuff placed on the patient's upper arm is inflated multiple times at a specific rhythm to improve mitochondrial function . The first cell culture experiment showed that an increase
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Cell Journal: There are many longevity proteins in the mitochondria of the brain
Time of Update: 2021-11-15
Krishna explained that the research team found that even if the mRNA is removed, these proteins remain in the cell for a long time and can maintain mitochondrial function .
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Nature: In addition to energy disorders, damage to mitochondria can also cause other kinds of Parkinson-like dyskinesias
Time of Update: 2021-11-14
>The role of mitochondria in Ndufs2-specific knockout mice on the 20th to 30th day after birth has changed: from energy producer to consumer, this is obtained from the sensitivity of the mitochondrial inner membrane (IMM) potential Further
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"Nature": How does mitochondria import antioxidants
Time of Update: 2021-11-12
Rockefeller University assistant professor Kivan Birsoy said: "With the identification of potential transporters, we can now control the amount of glutathione entering the mitochondria and specifically study the source of oxidative stress .
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Surprising: Mitochondria in diabetic patients cannot track time
Time of Update: 2021-11-02
These experiments demonstrate that mitochondria communicate with molecules that keep time within the cell, and this communication is interrupted in patients with type 2 diabetes .
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Chinese scholar PNAS published a paper: New discovery of cell mitochondria helps fight many diseases
Time of Update: 2021-09-19
Zhen Yan has been seeking a better understanding of how mitochondria work for many years, and he called this new discovery the most exciting of his career .
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Targeting mitochondria is expected to treat obesity
Time of Update: 2021-08-28
Scientists at the University of California, Irvine have discovered a new pharmacological approach that can reduce mitochondrial dysfunction that leads to diet-induced obesity
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Targeting mitochondria is expected to treat obesity!
Time of Update: 2021-08-28
A high-fat diet can lead to obesity and metabolic disorders such as diabetes and fatty liver . Palmitate, a fat rich in Western diets
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Scientists reveal the evolutionary fate of missing genes in mitochondria of gymnosperms
Time of Update: 2021-08-13
>The mitochondrial genomes of different biological lines are very different, especially compared to animals and other eukaryotes (the protein-coding gene content is relatively stable), the transfer/loss of mitochondrial genes in multiple branches of land
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Nature: How do cells control mitochondria
Time of Update: 2021-07-28
His team recently demonstrated the signaling mechanism in baker's yeast that can change the subunits of the TOM complex based on the metabolic state of the cell or in response to sudden stress .
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How cells control mitochondria
Time of Update: 2021-07-28
A signal protein called DYRK1A changes the molecular mechanism of TOM, making it more permeable to enzymes important for cell metabolism .