>After the new coronavirus invades the human body, it can cause a variety of immune cell responses.
Science | Song Yuanbin/Shan Liang et al. Develop a new humanized mouse model of human red blood cell growth and maturation
Time of Update: 2021-03-23
In recent years, Stephanie Halene, as the corresponding author, has published many research papers in internationally renowned journals such as Science, Immunity, Blood, and Nature Communications.
Zhang Zhi et al. reveal the neural mechanism of the side effects of the anti-breast cancer drug tamoxifen
Time of Update: 2021-03-22
Through tissue specificity Gene knockout and single-cell sequencing revealed that the estrogen receptor alpha (ERα) located in the hypothalamus is a key target that mediates tamoxifen's metabolic side effects such as hot flashes.
CD19 CAR-T causes neurotoxic syndrome, Stanford University et al. found the root cause
Time of Update: 2021-03-21
However, in addition to the cytokine storm, neurotoxicity is another type of toxic effect that has a high incidence and severely affects the lives of patients due to the related side effects caused by cell therapy.
BMS is working with insitro to develop drugs for ALS
Time of Update: 2021-03-07
BMS signed a five-year cooperation agreement with Machine Learning specialist Intro to develop drugs for the treatment of amyotrophic lateral sclerosis (ALS) and alzheimer's disease.
Eur Radiol: What is the value of the APT sequence in evaluating ALS patients?
Time of Update: 2021-02-25
Amyotrophic lateral sclerosis (ALS) is a deadly disease that usually begins with muscle weakness and has an average life expectancy of three to five years. current diagnosis of ALS relies heavily on the El Escorial standard, which requires
The German government has passed a draft law banning glyphosate al completely from 2024
Time of Update: 2021-02-24
German farmers will have to gradually reduce the use of glyphosate and stop using it al completely from 2024 to protect insect habitats, the World Agro-Chemical Network Chinese reported.
Al Jazeera Qatar: The benefits and harms of chewing gum are closely related to their composition and content
Time of Update: 2021-02-08
chewing gum may cause headache symptoms in people who themselves suffer from stress-type headaches or similar conditions, according to a study released just last month.
JNNP: Family clustering effect in genetic screening of 235 French ALS families
Time of Update: 2021-01-25
toxicity and defective axon transport, protein stabilization, autophagy, RNA metabolism, and mitochondrial abnormalities. currently, FALS accounts for 5% to 10% of ALS cases, and four genes (C9orf72, SOD1, TARDBP, FUS) account for about 60% of FALS
ALS-4, a new drug for methicillin-resistant Staphylococcus aureus (MRSA) infection, is about to begin phase I clinicalization
Time of Update: 2021-01-22
the main purpose of the trial was to assess the safety and tolerance of oral ALS-4 to healthy subjects.
The EU may ban the sale of perfluoric acid substances al into force in the first half of 2017
Time of Update: 2021-01-04
technical trade measures, especially REACH regulations on consumer goods in the control of harmful chemicals, in advance to prepare for the response. Second, timely improvement of product quality management system, due to the wide application
JNNP: Neuropathy Around ALS: Esothypetic Association
Time of Update: 2021-01-02
in a multi-center study, 88 ALS patients were surveyed, 12.5 percent of whom developed sensory multiple neuropathy (PNP), independent of age, course and site of onset.
Cancer Cell: Lu Min et al. found that frost can "resurrect" p53 mutants
Time of Update: 2020-12-31
Recently, Lu Min and other teams worked together at Cancer Cell to identify arsenic trioxide (ATO), a mature drug for acute primary myeloid leukemia that can act as a cysteine reactive compound to save structural p53 mutations.
JNNP: Rethinking of the functional evaluation scale for amyotrophic lateral sclerosis in ALS clinical trials
Time of Update: 2020-12-22
sensitivity of ALSFRS and ALSFRS-R to detect therapeutic effects with the signal-to-noise ratio and the required sample size.