cognitive decline, or it can be achieved by restricting such amino acids
Time of Update: 2021-04-18
Recently, researchers from Northwest A&F University in my country published a study titled Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21 in "Redox Biology".
Trends in Endocrinology & Metabolism: "Starve" cancer cells, the approach and challenge of amino acid depletion therapy
Time of Update: 2021-04-16
Recently, researchers from the Princess Marsima Pediatric Cancer Center of the Netherlands published a review article titled Amino Acid Depletion Therapies: Starving Cancer Cells to Death in the sub-Journal of Cell, Trends in Endocrinology & Metabolism (IF: 11.
50% of patients with rheumatoid arthritis are misdiagnosed and mistreated, and multiple drugs can help achieve standard treatment
Time of Update: 2021-04-13
would not be cured for a lifetime. "Many patients always resist the idea of life-long treatment, which is easily linked to the high price of medicines and side effects. Once the symptoms are relieved after taking
British scientists build a "portrait" of rheumatoid arthritis molecules, further research on chronic diseases
Time of Update: 2021-03-25
Lewis et al, Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes,, Cell Reports 28, 2455–2470
Progress in the asymmetric synthesis of N-substituted-α-amino acid esters
Time of Update: 2021-03-23
com/tags/%E5%B7%A5%E4%B8%9A%E7%94%9F%E7%89%A9%E6%8A%80%E6%9C%AF/">Industrial BiotechnologyThe research work is supported by the National Key Research and Development Program, the China Scholarship Council, the Chinese Academy of Sciences Youth Innovation Promotion Association, the British bioon.
Nature Sub-Journal: To solve these 3 problems, rheumatoid arthritis may also be cured!
Time of Update: 2021-03-22
Therefore, intestinal leakage may be a further driving factor for the influx of immune cells into the joints and promote disease recurrence.
Ann Rheum Dis: The safety of upatinib in the treatment of rheumatoid arthritis
Time of Update: 2021-03-21
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">the heart vascular events thrombosis Compared with adalimumab, patients with upatinib have an increased risk of herpes zoster and CPK.
Lancet rheumat: Targeting the proliferation of synovial fibroblasts, a new treatment direction for rheumatoid arthritis?
Time of Update: 2021-03-17
1016/S2665-9913(21)00061-8" target="_blank" rel="noopener">Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial .
The amino transfer reaction and the layer separation of amino acids in plant tissue
Time of Update: 2021-03-08
Instruments: research thermostat box centrifuge test tube 3 layering cylinders filter paper hair dryer pipe (0.5ml×3; 2ml×1) capillary tube 2.
NICE supports AbbVie's Rinvoq treatment for rheumatoid arthritis
Time of Update: 2021-03-06
She added: "We are optimistic that we can also make positive claims decisions for those patients with serious illnesses who currently have limited treatment options." (cyy123.com) : NICE backs AbbVie's Rinvoq for severe active rheumatoid arthritis
Analysis of Aliphatic Amino Acid Alcohols in Oxidized Proteins
Time of Update: 2021-03-05
Generic markers of protein oxidation such as protein carbonyls have been used longer as indices of protein oxidation in vivo ( 3 ) (reviewed recently inref.
Asymmetric Syntheses of Unnatural Amino Acids and Hydroxyethylene Peptide Isosteres
Time of Update: 2021-03-04
Chiral glycine equivalents serve as useful α-amino acid templates undergoing homologationvia carbon-carbon bond formation at the α-position through nucleophilic carbanion alkylation (2) or electrophilic carbocation substitution (3).
Progress has been made in the development of free amino acid monitoring sensors
Time of Update: 2021-02-28
free amino acids are small molecules of important metabolites in animals, and changes in the concentration of specific types or amino acids are of great significance to the evaluation of animal body nutrition and health status. At present
Nutritional Value of d-Amino Acids, d-Peptides, and Amino Acid Derivatives in Mice
Time of Update: 2021-02-28
The method is generally applicable to the determination of the biological utilization and safety of any amino acid derivative as a potential nutritional source of the correspondingl -amino acid.
rheumatoid arthritis promotes the occurrence of glioblastitis
Time of Update: 2021-02-26
, the study found that reduced IKAROS expression levels induced by increased ARC activity made T cells more reactive and ultimately led to chronic inflammation in RA and PSA.
Enzymatic Detection of d-Amino Acids
Time of Update: 2021-02-25
d -Amino acids play several key roles and are widely diffused in living organisms, from bacteria (in whichd -alanine is a component of the cell wall) to mammals (whered -serine is involved
Rinvoq has been approved by the European Union to treat rheumatoid arthritis
Time of Update: 2021-02-24
) to treat adult patients with moderate to severe active rheumatoid arthritis who do not respond adequately or to the MTX. Currently, an estimated 400,000 people in the UK suffer from rheumatoid arthritis, most of whom are not in remission. （cyy123.com）
Analysis of Neurotransmitter Amino Acids by CE-LIF Detection in Biological Fluids
Time of Update: 2021-02-24
Neurotransmitter amino acids like Alanine (Ala), Glutamic acid (Glu), Aspartic acid (Asp), Serine (Ser), Taurine (Tau), and Glycine (Gly) are widely distributed in biological fluids and tissues and they have important physiological
Branch chain amino acids: from fat-reducing fitness to infant development, can not be separated from it?
Time of Update: 2021-02-19
Several studies have shown that branched chain amino acids have potential effects in weight control, muscle synthesis, prevention of liver disease and promotion of infant development.
Gilead plans to apply for approval for the new rheumatoid arthritis drug Filgotinib
Time of Update: 2021-02-16
-drug treatment of filgotinib in combination with methotrexate and MTX primary patients. announcing the FINCH 3 study, Gilead and Galapagos said the phase III FINCH 1 trial reached the primary endpoint within 24 weeks with a 20