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Zhong Qing/Wang Weiwei, School of Basic Medical Sciences, et al. reported a new spray-type contrast agent that rapidly identifies tumor boundaries
Time of Update: 2023-02-03
During surgery, S-4-NP can be directly sprayed with the isolated tumor tissue section, and the tumor tissue can be clearly identified within 3 minutes through near-infrared imaging, thereby helping clinical surgeons quickly distinguish the boundary between tumor tissue and normal tissue, and judge the surgical margin (see Figure 3 for the complete imaging video).
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ALS global new drug research and development pattern: AAV, Treg, stem cells and other therapies into the clinic
Time of Update: 2023-02-03
the FDA accepted Tofersen's new drug application and granted it priority review status◆ WAVELife Sciences:WVE-004◆ WAVELife Sciences:WVE-004WVE-004 is an ASO drug developed by WAVELife Sciences for ALS and frontotemporal dementia (FTD) caused by mutations in the C9orf72 gene, designed to selectively target transcriptional variants containing hexanucleotide repeat amplification (G4C2) associated with the C9orf72 gene, thereby preserving the C9orf72 protein.
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Nature| Wu Taihong et al. revealed the neural mechanism of pathogenic microorganisms to change host social behavior
Time of Update: 2023-02-03
On January 4, 2023, Dr. Wu Taihong and Dr. Ge Minghai and other researchers from the team of Professor Yun Zhang's team from the Department of Evolutionary Biology and Center for Brain Science at Harvard University published a report entitled Pathogenic bacteria modulate pheromone in the journal Nature Response to Promote Mating's long study using Caenorhabditis elegans as a model animal reveals the neural mechanism by which pathogenic microorganisms alter the social behavior of host nematodes.
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Cell Yang Wuzhou et al. discovered the neural circuits that control the motor function of the hand
Time of Update: 2023-02-03
It also reveals the important role played by specific cerebral cortex-medullary nerve projection in controlling the aiming and manipulation functions of upper limb movement.
It also reveals the important role played by specific cerebral cortex-medullary nerve projection in controlling the aiming and manipulation functions of upper limb movement.
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Associate Professor Ni Qinxue, Zhejiang A&F University, et al.: Preparation of isoflavones and their protective effect on oxidative damage of RIN-m5F cells
Time of Update: 2023-02-02
Deng Ke, Chen Wei, Ni Qinxue* from the College of Food and Health of Zhejiang A&F University explored the enrichment process of potato isoflavone macroporous resin on the basis of tarato alcohol extract and ethyl acetate extract, and analyzed the antioxidant activity, α-glucosidase inhibition ability and protective effect of RIN-m5F cells on the basis of taro alcohol extract and ethyl acetate extract, in order to provide a theoretical basis for the subsequent development of functional foods.
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Professor Bi Yunfeng of Jilin Agricultural University, et al.: Protective effect of burdockinogenin on tetraoxamine-induced liver injury in diabetic mice
Time of Update: 2023-02-02
Gao Fei, Tang Jinxin, Bi Yunfeng* and others from the College of Food Science and Engineering of Jilin Agricultural University studied the protective effect of arctilin glycoside (ATG) on tetraoxamine-induced liver injury in DM mice, aiming to provide scientific basis for the prevention and treatment of DM-type liver injury and the development of ATG-related health care products.
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Nature Aging: Zeng Jianxiong et al. of the Chinese Academy of Sciences discovered the key mechanism
Time of Update: 2023-02-02
Information: style="margin-right: auto;margin-left: auto;outline: 0px;width: 30px;display: inline-block;">—END—The content is [iNature]iNatureCICL GMP SATASE (CGAS) DETECTS MICROBIAL AND HOST-DERIVED DOUBLE-STRANDED DNA IN THE CYTOPLASM TO TRIGGER CELLULAR INNATE IMMUNE RESPONSES IN A STIMULATOR OF INTERFERON GENES (STING)-DEPENDENT MANNER.
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Nat Methods Tian He et al. reported the optimization of far-infrared membrane potential probes based on optical hybrid screening technology
Time of Update: 2023-02-02
In the optical screening process, the authors first measured the membrane potential probe signals of thousands of mutant library cells in the imaging field of view, and used a digital micromirror array device (DMD) to accurately project violet light onto cells with both brightness and responsiveness.
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Professor Xu Hong, Nanjing University of Technology, et al.: Preparation of ε-polylysine
Time of Update: 2023-02-02
Prepare ε-PL-AOT complex, which is insoluble in water and soluble in ethanol, thereby forming a stable antimicrobial coating on the surface of plastic wrap (Figure 1).
Prepare ε-PL-AOT complex, which is insoluble in water and soluble in ethanol, thereby forming a stable antimicrobial coating on the surface of plastic wrap (Figure 1).
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Professor Liu Zhiyu, Fujian Fisheries Research Institute, et al.: Immunomodulatory mechanism
Time of Update: 2023-02-02
Malignant tumor has become a serious threat to human health and life safety of common diseases, chemotherapy is still one of the main treatments, however, chemotherapy drugs in the destruction of tumo
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Professor Yingyi Xu, Qiqihar University, et al.: Effects of heat treatment and transglutaminase on the properties of glycosylated oat protein gels
Time of Update: 2023-02-02
In order to better apply modified protein as an additive in the food industry, Xu Yingyi and Ma Xinrui from the School of Food and Biological Engineering of Qiqihar University heat treated oat protein and its glycosylation products and TG modified it, respectively, determined the structure and gel properties of modified protein gel, and explored the effect of glycosylation modification combined with heat treatment or TG modification on the gel properties of oat protein.
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Associate Professor Tao Han, Guizhou University, et al.: Construction of white kidney bean esterase
Time of Update: 2023-02-02
As the most widely used pesticides in modern agriculture, organophosphorus pesticides (OPPs) play an important role in protecting crops from pests and increasing crop yields. Unfortunately, due to its
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Food Science: Professor Luo Ruiming, Ningxia University, et al.: Effects of ATPase activity changes
Time of Update: 2023-02-01
2. Changes in the microstructure of the longest muscles and degradation of myofibrillar protein during post-slaughter maturation Tan sheep are high-quality characteristic breeds distributed in Shaanxi, Gansu and Ningxia, and are loved by consumers because of their delicious meat and rich nutrition.
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Redox Biol—Xinong Liu Zhigang et al. revealed for the first time that methionine-restricted diets can improve AD cognitive dysfunction
Time of Update: 2023-02-01
Professor Liu Zhigang and others published a title entitled " Effects of methionine intake on cognitive function in mild cognitive impairment patients and APP/PS1 Alzheimer's Disease model mice: Role of the cystathionine-β-synthase/H 2S pathway" research paper, the authors first studied in a survey of 45 people diagnosed with mild cognitive impairment (Mild Cognitive Impairment, MCI) and a cohort of 61 healthy controls without cognitive impairment found a positive association between methionine intake and an increased risk of MCI.
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Qingdao Energy Institute et al. proposed a new technology for repairing formamidine-based perovskite thin films after ammonia gas
Time of Update: 2023-02-01
Perovskite solar cells are an emerging photovoltaic technology. After development, their photoelectric conversion efficiency is comparable to that of silicon cells. It is considered to be a new genera