-
Nature sub-issue 1 published 2 articles: The new oncolytic virus is equipped with dual antibodies
Time of Update: 2023-01-06
Official website of each company——List of recent popular events——November 23, Key Elements of Quality Control for mRNA VaccinesNovember 19, 2022 / eMedClub News / -- November 17, 2022, Nature Cancer In an article titled "An armed oncolytic virus for GBM destruction," an oncolytic herpes simplex virus (oHSV) that carries a bispecific EGFR-CCL5 antibody fusion protein that activates innate and adaptive anti-tumor immune responses has shown extremely high efficacy in preclinical models of glioblastoma (GBM).
-
Nature sub-issue 1 published 2 articles: The new oncolytic virus is equipped with dual antibodies
Time of Update: 2023-01-06
Official website of each company——List of recent popular events——November 23, Key Elements of Quality Control for mRNA VaccinesNovember 19, 2022 / eMedClub News / -- November 17, 2022, Nature Cancer In an article titled "An armed oncolytic virus for GBM destruction," an oncolytic herpes simplex virus (oHSV) that carries a bispecific EGFR-CCL5 antibody fusion protein that activates innate and adaptive anti-tumor immune responses has shown extremely high efficacy in preclinical models of glioblastoma (GBM).
-
1 article in Nature + 1 Cell sub-journal reveals that tumor bacteria help tumor progression and resistance to treatment
Time of Update: 2023-01-01
Dr. Susan Bullman, a cancer microbiome researcher at Fred Hutchinson Cancer Center and co-corresponding author of the two studies, said of the first study, "What we showed is that in some areas of the tumor, --- micro-niche regions, there is a large number of bacterial colonizations that are functionally different from areas without bacteria.
-
Zhejiang University team interpretation: nearly 1/3 of children infected with Helicobacter pylori
Time of Update: 2022-10-03
Introduction to research papersScreenshot credit: The Lancet Child & Adolescent HealthIn this study, the team searched for population-based observational studies published between the inception of the database and October 25, 2021 in mainstream foreign language literature databases (PubMed, Embase, MEDLINE, and Scopus), and finally included 198 articles (all cross-sectional studies) reporting Hp infection rates in children aged 18 years and younger, covering a total of 632 data points and 152,650 children.
-
JAMA Sub-Issue: 29 Years follow-up report revealed! Recognized as "women have a lower risk of cardiovascular disease", why did type 1 diabetes roll over?
Time of Update: 2022-09-20
This study compared cardiometabolic risk factor profiles, cardiac protection drug use, and CVD events in men and women with type 1 diabetes and followed up for approximately 29 years in the Diabetes Control and Complications Trial/Diabetes Intervention and Complication Epidemiology (DCCT/EDIC) study.
-
Nature Sub-Journal: Closed-loop insulin delivery systems may help with brain development in children with type 1 diabetes
Time of Update: 2022-09-15
This is a proof-of-concept pilot study that reports that a mixed closed-loop insulin delivery system can reduce the occurrence of hyperglycemia and glucose variants, or improve brain development and cognitive function in adolescents with type 1 diabetes.
-
Lancet Sub-Journal: In 1 in 4 hospitalizations, what is the impact of delirium on long-term cognitive impairment and mortality?
Time of Update: 2022-04-24
The clinical importance of delirium has been demonstrated as acute changes in arousal, inattention, and overall cognitive impairment, affecting 1 in 4 elderly (≥70 years of age) hospitalized patients .
-
BM Sub-Journal: True body weight change, compliance and discontinuation of GLP-1 receptor agonists in T2DM patients
Time of Update: 2022-03-04
1136/bmjdrc-2021-002517Reference: Weiss T, Yang L, Carr RD, et al Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK BMJ Open Diabetes Research and Care 2022; 10:e002517.
-
BMJ Sub-Journal: What are the predictors of arteriosclerosis in patients with type 1 diabetes?
Time of Update: 2022-02-17
Diabetes mellitus (DM) is a cardiovascular risk factor closely associated with arteriosclerosis, and the aim of this study was to determine which hemodynamic and demographic factors could predict arteriosclerosis in this population .
1136/bmjdrc- 2021-002491 doi: 10.
-
BMJ Sub-Journal: What are the signs of fat hypertrophy in patients with type 1 diabetes, and how should this degree of hypertrophy be evaluated?
Time of Update: 2022-01-07
1136 /bmjdrc-2021-002553References: Hashem R, Mulnier H, Abu Ghazaleh H, et al Characteristics and morphology of lipohypertrophic lesions in adults with type 1 diabetes with ultrasound screening: an exploratory observational study BMJ Open Diabetes Research and Care 2021;9:e002553.
-
Explore the headline Cell sub-published two articles in a row: Islet stem cell transplantation is expected to end type 1 diabetes
Time of Update: 2021-12-26
Stem cell-derived PEC-01s (pancreatic endoderm cells that survive 26 weeks after implantation and become glucose-sensitive and insulin-secreting cells) can mature into glucose-responsive, insulin-producing mature β cells in patients with type 1 diabetes During the one-year follow-up, the patient’s insulin requirements were reduced by 20% and the time spent in the target blood glucose range increased by 13% .
-
BMJ Sub-Journal: Is DKA the only favorite for type 1 diabetes?
Time of Update: 2021-12-26
However, it is also recognized that DKA can also occur in patients with type 2 diabetes; a recent retrospective cohort study estimated that the incidence of DKA in type 2 diabetes increased by 4.
-
BMJ Sub-Journal: The long-term incidence trend of type 1 and type 2 diabetes and the impact of population aging on mortality in China from 1990 to 2019
Time of Update: 2021-11-12
Although there are two studies in management Use the Global Burden of Disease (GBD) database to analyze the incidence trend of diabetes in China , but their results combine type 1 diabetes (T1DM) and type 2 diabetes (T2DM) into one category for analysis .
-
The pCR rate of the neoadjuvant PD-1 monoclonal antibody for the treatment of colorectal cancer
Time of Update: 2021-11-04
486) published online the latest research results in the field of colorectal cancer immunotherapy by Professor Deng Yanhong's team at the Sixth Affiliated Hospital of Sun Yat-sen University——" Neoadjuvant teriprimab (anti-PD-1 monoclonal antibody) with or without celecoxib (COX-2 inhibitor) for the treatment of mismatch repair protein defects (dMMR) or highly unstable microsatellites (MSI-H) ) Single-center, parallel, non-controlled, randomized, phase II clinical trial (PICC) for locally advanced colorectal cancer" .
-
Lancet Sub-Journal & WCLC: A single chest CT screening can reduce lung cancer mortality by 1/3!
Time of Update: 2021-09-29
The NLST report shows that through low-dose CT (LDCT) screening three times a year, lung cancer mortality has been significantly reduced by 20% .
The NLST report shows that through low-dose CT (LDCT) screening three times a year, lung cancer mortality has been significantly reduced by 20% .