interventions, even modestly delaying the onset of dementia, can have major public health implications . There are currently no disease-modifying treatments
Nat Med: Bloodborne tumor mutational burden as a biomarker for atezolizumab therapy in non-small cell lung cancer
Time of Update: 2022-05-21
cancer (NSCLC) whose tumors express highly programmed Death Ligand 1 (PD-L1) . In retrospective studies, tumor mutational burden (TMB) in circulating tumor DNA (ctDNA) is promising in predicting
Cancer Med: New achievements of Chinese scientists!
Time of Update: 2022-05-20
Image Credit: Unsplash/CC0 Public DomainIn this study, the researchers used exosomes produced by specialized cells called lipid-derived mesenchymal stem cells (ADSCs) to deliver RNA-based (miR-138-5p) Anticancer therapy, which effectively treats bladder cancer in mice .
Nat Med: Scientists reveal gut microbes correlate with tumor immunotherapy response
Time of Update: 2022-05-20
The findings were published in Nat Med under the title "Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1" .
Over $10 billion in anticoagulants!
Time of Update: 2022-05-19
Since April, there have been frequent reports of good news from Huahai Pharmaceutical .
Med J Aust: Opioid therapy may be suboptimal for pain relief in patients with osteoarthritis
Time of Update: 2022-05-15
RESULTS: Results from 19 trials (including 8965 participants; dose range, 10-126 MME/day) showed a small benefit of opioids for mid-term pain relief (mean difference [MD], -4.
Am J Sports Med: Platelet-rich plasma with or without leukocytes does not affect efficacy in the treatment of knee osteoarthritis
Time of Update: 2022-05-14
In conclusion, this double-blind randomized trial showed that 3 intra-articular LR-PRP or LP-PRP injections produced similar clinical improvement in patients with symptomatic knee OA at 12-month follow-up .
Ann Intern Med: Effects of parathyroidectomy on morbidity and mortality in patients with mild hyperparathyroidism
Time of Update: 2022-05-13
This study was a prospective randomized controlled trial to evaluate the effect of parathyroidectomy on mortality (primary endpoint) and important disease morbidity (secondary endpoint) in patients with mild PHPT .
Ann Intern Med: Influence of frailty on the efficacy and safety of dapagliflozin in heart failure patients with reduced ejection fraction
Time of Update: 2022-05-13
The study aimed to explore the role of dapagliflozin in DAPA-HF (dapagliflozin prevention of heart failure) using the Rockwood cumulative loss method according to the patient's frail status.
Nat Med uses artificial intelligence to safely detect cancer from patient data
Time of Update: 2022-05-13
Swarm learning trains artificial intelligence algorithms to detect patterns in local hospital or university data, such as genetic changes in images of human tissue .
Ann Intern Med: Mortality and morbidity in mild primary hyperparathyroidism
Time of Update: 2022-05-12
Mortality and Morbidity in Mild Primary Hyperparathyroidism: Results From a 10-Year Prospective Randomized Controlled Trial of Parathyroidectomy Versus Observation .
Nat Med: Donor and recipient polygenic risk scores influence the risk of posttransplant diabetes
Time of Update: 2022-05-11
The researchers applied PRS for T2D to liver and kidney transplantation, aiming to clarify the independent or synergistic relationship between recipient and/or donor genes and the development of PTDM .
BMC Med: Recovery of serum testosterone levels is an accurate predictor of COVID-19 survival in male patients
Time of Update: 2022-05-08
e. Correlation of serum testosterone levels with lymphocyte (percent and count of white blood cells) and neutrophil countsFigure 2 Assessment of clinical biochemical parameters as predictors of risk of severe illness or death from COVID-19 .
Sichuan pharmaceutical company will win over $10 billion in anticoagulant drugs
Time of Update: 2022-05-03
A few days ago, Chengdu Baiyu Pharmaceutical entered the administrative examination and approval stage with its generic apixaban tablets, which were reported for production in Category 4
This anticoagulant drug market with sales of over 100 million has added another entrant!
Time of Update: 2022-05-02
Anticoagulant drugs refer to drugs that prevent blood coagulation, and are mainly used for the prevention and treatment
