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BeiGene Chairman Lei Qiang Ou: After 2024, it is expected that 10 new molecules will enter the clinical JPM conference every year
Time of Update: 2023-02-01
Anti-PD-1 monoclonal antibody tislelizumab ▲BeiGene's internal R&D pipeline (Image source: Screenshot of BeiGene's speech report)▲BeiGene's internal R&D pipeline (Image source: BeiGene speech report screenshot) ▲▲Bcl-2 inhibitor BGB-11417: In the second half of 2023, a global pivotal trial in combination with zebratinib for the first-line treatment of CLL will be initiated, and data from ongoing clinical studies is expected to be available.
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Lei Xiaoguang's team completed the first biomimetic total synthesis and biological mechanism study of the natural product Fargesone A
Time of Update: 2023-02-01
As an important member of the nuclear receptor family, Farnesoid X receptor FXR (Farnesoid X Receptor) is highly expressed in the liver and small intestine, and has an important regulatory function f
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Lei Xiaoguang's research group and collaborators in the School of Chemistry discovered a new way to cure "itch"
Time of Update: 2023-01-06
Su Dongpo said: "It's easy to endure pain, but it's hard to endure itching. " Modern science has found that both pain and itching are regulated by specific neural circuits, but many times, itching is
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Lei Xiaoguang's research group and collaborators in the School of Chemistry discovered a new way to cure "itch"
Time of Update: 2023-01-06
Su Dongpo said: "It's easy to endure pain, but it's hard to endure itching. " Modern science has found that both pain and itching are regulated by specific neural circuits, but many times, itching is
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The research group of Chen Lei of the School of Future Technology revealed the inhibition mechanism of the human glucose transporter SGLT1
Time of Update: 2022-11-25
Sodium-glucose co-transporter (SGLT) is an important transporter responsible for glucose reabsorption in the human body, enabling the reverse concentration gradient transport of glucose using the ele
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Showcasing a zero-carbon future at the CIIE - Lei Huanli, Senior Vice President and President of Covestro China, gave a talk
Time of Update: 2022-11-25
Huanli Lei, Senior Vice President and President of Covestro China, said: "Covestro has always adhered to its commitment to circular economy and sustainable development, fully demonstrated the concept of low-carbon environmental protection at the Expo, and created a zero-carbon booth to contribute to the realization of climate neutrality.
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Lei Zuhai's research group has made progress in the ratiometrically responsive near-infrared two-region fluorescence molecular imaging platform
Time of Update: 2022-11-15
Probe response mechanism and its application in tumor hypoxic imagingIn this work, a molecular platform Py-2 with emission in the NIR region was designed, which has good universality, based on which two ratiometric molecular fluorescent probes were constructed and the visualization and quantitative monitoring of biomolecules such as enzymes and ROS/RNS in living deep tissues was realized.
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Li Lei's team at ShanghaiTech University found that ALS mutant genes regulate DNA damage repair
Time of Update: 2022-11-15
6s ease 0s;letter-spacing: normal;font-size: 12px;" _mstmutation="1" _istranslated="1"> Open reprint welcome to forward to Moments and WeChat groups Amyotrophic lateral sclerosis, also known as ALS)is a rapidly progressive neurodegenerative disease that affects up and down motor neurons.
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How do breast cancer patients choose the best treatment option? Professor Fan Lei has face-to-face communication with you about "medical"
Time of Update: 2022-11-01
*For medical professionals only to read and refer to Pink Ribbon Moon DialogueProfessor Fan Lei, Department of Breast Surgery, Fudan University Cancer HospitalWith the advancement of medical technolog
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Lei's team at the Institute of Medicine of Northwestern Polytechnical University applied electrical
Time of Update: 2022-11-01
Wang Lei's team at the Institute of Medical Science of Northwestern Polytechnical University has been committed to the research of electrical impedance tomography applied to epileptic foci localization, seizure detection and prediction.
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The laboratory of Li Lei, College of Modern Agriculture, Peking University, discovered the genetic mechanism of the origin of miRNA in angiosperms
Time of Update: 2022-10-25
A model of MITE-miRNA evolution in angiosperms Guo Zhonglong, a doctoral graduate of Peking University and currently working at Nanjing Forestry University, is the first author of the paper, and researcher Li Lei of Peking University and Yang Xiaozeng, researcher of Beijing Academy of Agriculture and Forestry Sciences, are co-corresponding authors of the paper.
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Xiao Lei's team at Fudan University revealed the circuit mechanism of dopamine type 1 receptors regulating anxiety behavior
Time of Update: 2022-10-21
Figure 1: Anxiolytic and anxiolytic effects of D1 receptors2Different types of neurons expressing D1 receptors regulate anxiety behaviorAcute activation by optogenetics or chronic activation of D1 receptor-positive neurons in the VTA brain region promoted the residence time of mice in the central region of the open field experiment, increasing the time of mice in the open arm, while chronic inhibition of the neuron caused anxiety-like behavior in mice.
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Professor Lei's research group published an article in the Journal of Occupational Health
Time of Update: 2022-10-20
Based on the perspective of resources, this study proposes that high-quality leader-subordinate exchange relationships provide employees with important work-related resources (e.
Based on the perspective of resources, this study proposes that high-quality leader-subordinate exchange relationships provide employees with important work-related resources (e.
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Xiao Lei's team revealed the regulatory role and loop mechanism of VTA D1 neurons on anxiety-like behavior
Time of Update: 2022-10-13
On October 4, 2022, Xiao Lei's team of young researchers from the Institute of Brain Sciences/State Key Laboratory of Medical Neurobiology of Fudan University published online on Molecular Psychiatry titled "D1 receptor-expressing neurons in ventral tegmental area alleviate mouse anxiety-like behaviors via.
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Science Advances Jiao Yuling Group and Mathematical Center Zhang Lei..
Time of Update: 2022-09-07
Therefore, this study proposes a "seesaw" model - auxin signaling simultaneously activates the expression of REV and KAN1 to stably maintain the coexistence of the two regions, thereby theoretically maintaining the developmental pattern .