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Eur Respir J: Large-scale genome-wide association analysis of the Chinese population found a new location in lung function
Time of Update: 2021-11-02
Lung function is a heritable complex phenotype, and obesity is one of its important risk factors . However, the relevant knowledge about the common genetic basis of the two is still limited . Most p
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Cereb Cortex transcription-neuroimaging association analysis reveals the genetic mechanism
Time of Update: 2021-10-21
Figure 2 Functional enrichment results of genes related to occipital visual subregion rsFC (picture quoted from: Cun Zhang, et al.
, Cerebral Cortex, 2021; bhab335) Figure 3 Specificity of genes related to occipital visual subregion rsFC Expression analysis results (picture quoted from: Cun Zhang, et al.
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variation association analysis to identify and verify the prognostic markers of bladder cancer lncRNA
Time of Update: 2021-10-01
Content Introduction Chinese Abstract: Objective: To investigate the role of long non-coding RNAs (LncRNAs) with copy number variation (CNV) in bladder cancer .
Integrative analysis of prognostic long non-coding RNAs with copy number variation in bladder cancer[J].
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"Raman intragroup association analysis" reveals metabolite transformation network
Time of Update: 2021-09-28
Chinese Academy of SciencesChineseAcademy ofSciencesChineseAcademy of Sciences ChineseAcademy ofSciencesmBio It is reported that without the need to label or destroy cells, the "Raman intra-group association analysis" algorithm is only based on a Raman group data point, that is, a state of a sample, and the difference in the Raman spectra of different single cells can be used.
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Nat Genet: A genome-wide association analysis of 100,000 plus cases identified 86 new prostate cancer susceptible mutations
Time of Update: 2021-01-17
In this study, researchers consolidated genome-wide association analysis (GWAS) data from 107,247 cases of prostate cancer and 127,006 controls (from Europe, Africa, East Asia and Spain) to identify common genetic variants associated with disease risk in populations.
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Diabetogia: Two-way association analysis between severe depression and cardiovascular metabolic disease
Time of Update: 2020-06-25
Observational studies show a two-way association between severe depression (MDD) and heart and metabolic diseases just published in Diabetogia, analyzed the two-way causal effects of MDD and cardi
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AJG: Epidemiology and outcome analysis of colorectal cancer associated with inflammatory bowel disease
Time of Update: 2023-01-05
This study analysed using population data from the UK National Health Service held in the CRC database to include all CRCs diagnosed with IBD (Crohn's disease, ulcerative colitis, IBD unclassified, and IBD with cholangitis) between 2005 and 2018.
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Neurology: Air pollution associated with event-induced stroke, post-stroke cardiovascular events, and death: a trajectory analysis of a prospective cohort
Time of Update: 2023-01-04
This study provides the first evidence that ambient air pollution is an important correlated factor in progressive stroke and has a different effect at different clinical stages.
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Ningxia Chemical Analysis and Testing Association issued four food safety group standards related to wine testing
Time of Update: 2023-01-04
【Chemical Machinery and Equipment Network Industry News】Recently, Ningxia Chemical Analysis and Testing Association released four group standards: "Artemisia noodles", "Determination of alcohol content and total extracts in wine by near-infrared-density method", "Quality specification for wine grape juice" and "Determination of total sulfur dioxide in wine Inductively coupled plasma emission spectrometry", which have been officially implemented since November 1, 2022.
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JNNP: Chinese clinical and genetic analysis of familial optic neuromyelitis lineage disorders
Time of Update: 2022-10-12
The functional effects of single nucleotide polymorphisms (SNPs) of the ubiquitin-specific peptidase USP18 gene were predicted, and their genetic variants were associated with disease.
The functional effects of single nucleotide polymorphisms (SNPs) of the ubiquitin-specific peptidase USP18 gene were predicted, and their genetic variants were associated with disease.
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Nature communications Transcriptomic analysis to reveal genes associated with selective hippocampal susceptibility in Alzheimer's disease
Time of Update: 2022-10-09
1038/s41467-021 -22399-3 Transcriptomic analysis to reveal genes associated with selective hippocampal susceptibility in Alzheimer's diseaseREADINGAlzheimer's disease (AD)Alzheimer's disease (AD) is a multifactorial neurodegenerative disease characterized by the abnormal accumulation of two misfolded proteins, tau and beta amyloid (Aβ) .
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Data analysis of more than 8 million hospitalizations in China: Is it only wallets that hurt
Time of Update: 2022-10-02
The daily absolute return of the Shanghai or Shenzhen index correlates significantly with the increase in hospital admissions for total CVD, ischemic heart disease, stroke and heart failure nationwide (Figure 4).
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Ann Transl Med: analysis of m6A-related features associated with the tumor immune microenvironment and prediction of survival in acute myeloid leukemia
Time of Update: 2022-09-30
The research team built a prognostic model using m6A-related features associated with TIME to predict the survival of AML patients.
The research team built a prognostic model using m6A-related features associated with TIME to predict the survival of AML patients.
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A new data analysis method identifies splicing variants associated with disease
Time of Update: 2022-09-21
Source: Department of Genomic Function and Diversity, TMDUResearchers from Tokyo Medical and Dental University (TMDU) have found that integrating and selectively analyzing spliced variant data can help identify genetic variants associated with complex human diseases In the era of big data, access to a lot of information is the easiest part; Knowing how to take advantage of it is another matter entirely.
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Diabetologia: A genome-wide crossover trait analysis identifies shared loci and causal associations
Time of Update: 2022-09-06
Objectives: In the current study, we aimed to investigate type 2 diabetes, glycemic traits and independence of body mass by performing a comprehensive genetic analysis using the largest genome-wide association study (GWAS) summary statistics for each trait to date Exponential shared genetic contributions among PCOS .
