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Author: Liz Zee Introduction
Professor Chen Qijun's research group revealed that dihydroartemisinin regulates spleen immune cell heterogeneity through SOD3-JNK-AP-1 signaling pathway
Time of Update: 2022-05-01
group from Shenyang Agricultural University published a research paper entitled "Dihydroartemisinin beneficially regulates splenic immune cell heterogeneity through the SOD3-JNK-AP-1 axis" in Science China Life Sciences, revealing that DHA regulates
transcription factor in T cell immune memory and secondary immune response
Time of Update: 2022-05-01
and stimulate the immune response again. This process is called immune memory and secondary immune response . An in-depth understanding of the molecular mechanisms of immune
induces immune tolerance by regulating CD8+ T cell thymus development
Time of Update: 2022-05-01
with chronic infection. However, its detailed cellular and molecular mechanisms are still unclear . Recently, Yuan Zhenghong's team from the Department of Pathogenic Biology
Cell sub-issue: Qiu Ju's team discovered the regulatory role of Setd2 on type 3 innate lymphocytes and intestinal immunity
Time of Update: 2022-04-29
Recently, the international academic journal Cell Reports published online the latest research results titled "Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity
Behind the scenes of type 1 diabetes: immune T cells that won't be exhausted "Nature" paper recommended
Time of Update: 2022-04-29
Authors: Stephen J. Turner & Nicole L. La Gruta The discovery that a specific subset of immune system T cells contributes to type 1 diabetes not only sheds new light on autoimmune
Cell's novel immune adjuvant mannan
Time of Update: 2022-04-28
The C-type lectin receptors (CLRs) Dectin-1 and Dectin-2 in the PRR can recognize the cell wall polysaccharides β-glucan and mannose to regulate innate and adaptive immune responses in fungal infections .
Immunity: Antibacterial effects of a new subpopulation of intestinal epithelial cells, Tuft-2 cells and its mechanism
Time of Update: 2022-04-27
On March 22, 2022, Fan Zusen's group from the Institute of Biophysics, Chinese Academy of Sciences published an article titled "Intestinal Tuft-2 cells exert antimicrobial
Immunity Reveals Antitumor Mechanism of Tertiary Lymphoid Structure in Renal Cell Carcinoma Using
Time of Update: 2022-04-26
/>Figure: Tertiary lymphoid structure, from 2019 Nature Reviews Cancer The tertiary lymphoid structure can be seen as a lymphocyte aggregate built on a network of fibroblasts, including two important structural areas - the T cell area
Cell: Improving cellular responses and mixed immunity
Time of Update: 2022-04-25
"Vaccines alone are very good at preventing disease; they just don't produce as diverse an immune response as a post-vaccination infection," said Marion Pepper, an associate professor in Washington University's Department of Immunology who led the study.
Cancer Discovery: Novel immune checkpoint: can be used to enhance T cells against cancer, and also allows CAR-T to fight solid tumors
Time of Update: 2022-04-23
Cancer Discovery PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor ImmunityThe study found that inhibiting protein tyrosine phosphatase 1B (PTP1B) on T cells mobilized the body's immune response to cancer and helped suppress tumor growth .
them to bypass the immune system to attack cancer cells
Time of Update: 2022-04-23
. So what if we changed our minds and instead of knocking out these antigenic molecules, we concealed them?>Therefore, another alternative strategy is to coat microbial
Study shows long-term safety of genetically modified immune effector cells
Time of Update: 2022-04-22
A new study by researchers at the Center for Cell and Gene Therapy at Baylor College of Medicine shows that patients receiving genetically modified immune cells ( IECs)-treated cancer patients did not have an increased risk of subsequent malignancies .