Sci Adv: Scientists hope to develop novel therapy for small cell lung cancer
Time of Update: 2022-05-23
of the EP300 KIX domain in the treatment of novel therapeutic interventions . (Bioon. com)>Original source:>KEE-BEOM KIM, ASHISH
An important step in the development of biological enamel
Time of Update: 2022-05-19
That's why Professor Hugo Vankelecom's team at KU Leuven, in collaboration with UHasselt, developed a 3D research model using stem cells from a dental follicle, a membranous tissue surrounding an unerupted human tooth .
Changzhou develops a new type of spray dryer in one step
Time of Update: 2022-05-09
effectively avoid the incorporation of iron ion impurities and maintain the conductivity of the positive electrode material; it adopts pulse dust removal and cooling protection technology, and realizes cooling protection safety interlocking under
"Science" How many steps does it take to accurately transform normal cells into cancer cells?
Time of Update: 2022-05-09
> >These edited cells grew and proliferated into tumors with melanoma characteristics, including rapid growth, enhanced invasiveness, and specific patterns of gene activation and pigmentation
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Good news for patients with malignant blood cancer Gamida Cell stem cell transplant product is one step closer to approval
Time of Update: 2022-05-02
On February 9, 2022, Gamida Cell announced that it has initiated rolling submissions to the U.
S.
FDA
induces immune tolerance by regulating CD8+ T cell thymus development
Time of Update: 2022-05-01
with chronic infection. However, its detailed cellular and molecular mechanisms are still unclear . Recently, Yuan Zhenghong's team from the Department of Pathogenic Biology
Promoting the development of precision medicine AI-driven single-cell analysis platform receives US$73 million
Time of Update: 2022-04-30
The company's technology platform combines AI, proprietary microfluidics, high-resolution optics, and a growing cell atlas, which contains more than 1 billion visual feature-based images to analyze and classify cells, according to the press release .
FDA issues draft guidance on development considerations for CAR-T cell therapy
Time of Update: 2022-04-30
In the draft guidance, the FDA provides specific recommendations for CAR-T cells on chemistry, manufacturing and control (CMC), pharmacology and toxicology, and clinical study design .
On the Cell: Wei Wensheng's team develops a circular RNA vaccine that is effective against Delta and Omicron
Time of Update: 2022-04-27
Domain (RBD) circular RNA vaccine (circRNA-RBD) was able to elicit potent neutralizing antibodies and T cell responses, resulting in effective protection against Delta and Omicron mutants .
Changzhou develops mixed flow dryer in one step
Time of Update: 2022-04-26
At present, the mixed flow dryer has different models from DYP-6 to 800 according to the maximum water evaporation.
NBT Dai Qionghai and others developed an artificial intelligence method for fusion analysis of cell microscopic images and genetic data—MUSE
Time of Update: 2022-04-25
> Based on the research group's accumulation in optical microscopy (Cell 2021, Nature Photonics 2019, 2020), single-cell gene analysis technology (Nature Methods 2019) and cross-application of artificial intelligence (Nature
Cell Wei Wensheng's research group reported the circular RNA technology platform and the new anti-new coronavirus vaccine developed accordingly
Time of Update: 2022-04-18
of neutralizing antibodies in the body, which can more effectively fight against virus mutation and reduce the potential side effects of antibody-dependent enhancement (ADE) of the vaccine; 3) The ratio of IgG2/IgG1 induced by circRNA vaccine is higher
Cell: Analyze the latest portrait of HIV virus to promote the development of AIDS vaccine
Time of Update: 2022-04-18
Cryo-ETof Env on intact HIV virions reveals structural variation and positioning on the Gag latticeThe study uncovered new details about the human immunodeficiency virus (HIV) using powerful tools and techniques developed in the field of structural biology .
Nature: What makes brain cells develop in a specific order
Time of Update: 2022-04-15
processes in future laboratories, generating specific types of neurons in petri dishes and potentially transplanting them into patients, or in living organisms Trigger neural stem cells to generate and replace missing neurons
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Delivering good news to patients with malignant blood cancer, innovative stem cell transplant products are one step closer to approval
Time of Update: 2022-03-09
▎WuXi AppTec Content Team Editor On February 9, 2022, Gamida Cell announced that it has initiated rolling submission of the Biologics License Application (BLA) for the stem cell/bone marrow transplant product omidubicel to the U.
Fasting can improve efficacy of liver cancer drugs and even prevent cancer cells from developing resistance to them | Science Advances
Time of Update: 2022-03-09
Identify QR codes Read open access papers Science Advances Guide column *The compiled content is for reference only, the academic content is subject to the paper.
Molecular mechanism of Cell Stem Cell E3 ubiquitin ligase TRAF6 regulating the development of myeloid malignancies
Time of Update: 2022-03-09
e. hematopoietic stem progenitor cells) can proliferate clonally in vitro and in vivo, and proved that TRAF only works in CHIP-related gene mutations (such as TET2) can promote the malignant transformation of pre-leukemia hematopoietic stem progenitor cells .
Nature Cancer answers mystery: How cancer cells develop into metastatic cancer after years of dormancy
Time of Update: 2022-03-08
In mouse models, when the scientists increased the amount of type III collagen around tumor cells, cancer progression was interrupted, and disseminated cells were forced into a dormant state .
panorama of single-cell early development of rice inflorescence
Time of Update: 2022-03-08
The researchers used a single-cell sequencing system to map a dynamic panorama of early rice inflorescence development, reconstructing the developmental trajectories of rice spikelets, flowers, and various reproductive meristems .
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