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Cell Death Dis:LINC01559 activates the PI3K/AKT signaling path path, which promotes the development of stomach cancer.
Time of Update: 2020-09-24
a variety of cellular functions, including cell proliferation, migration, and stem cell properties. , however, the level and function of LINC01559 in stomach cancer (GC) has yet to be studied. the study, based on analysis from the GEPIA
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Fda approved Kesimpta, the first and only self-injected B-cell therapy for patients with multiple sclerosis, to be injected once a month.
Time of Update: 2020-09-24
positive results from the APLIOS study in phase II of the study showed that RMS patients were biologically equivalent to Kesimpta injections with pre-installed syringes and Sensoready pens.
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npj Precision Oncology: Amazing! The venom of small bees is of great use and can kill cancer cells 100% in in-body experiments.
Time of Update: 2020-09-24
another excellent example of how natural compounds can be used to treat human diseases. , this study provides a reference for assisting in the development of new treatments for a variety of cancers associated with frequent drug resistance
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Hengrun Dasheng completed 200 million yuan B-plus round of financing, plus code cell therapy industrialization layout.
Time of Update: 2020-09-24
Recently, Zhangjiang Science City cell therapy company Shanghai Hengrun Dasheng Biotech Co., Ltd. (hereinafter referred to as "Hangrun Dasheng") announced the completion of 200 million yuan B-plus round of financing, Pudong Science Group, China New
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FDA approves Gawreto (pralsetinib) treatment for metastasis RET fusion positive for non-small cell lung cancer.
Time of Update: 2020-09-24
, a member of the Roche Group, announced today that the U.S. Food and Drug Administration (FDA) has approved Gawreto™ (pralsetinib) for the treatment of metastasis RET fusion positive non-small cell lung cancer (NSCLC) patients.
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The European Union has approved the first-line treatment of imfinzi (durvalumab) for the widespread treatment of small cell lung cancer.
Time of Update: 2020-09-24
The first immunotherapy in patients with widespread small cell lung cancer that improves both survival and response rates," said Dave Fredrickson, executive vice president of Oncology at AstraZeneca.
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Cell Death Dis:PLC? is critical to maintaining the function of AR signals in prostate cancer.
Time of Update: 2020-09-24
(phospholipidase C) was highly expressed in CaP samples, and that the high expression level was closely related to the activity of ar signal transduction path.
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Cell Death Dis: ASC regulates the stability of HIF-1 alpha to induce the metastasis of squamous cell carcinoma in the mouth.
Time of Update: 2020-09-24
researchers identified 195 genes associated with cellular movement that were highly SAS_ASC in ASC-expressed cells.
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Genome Medicine: Reveals the important role of non-coded RNA in the progression of non-small cell lung cancer and tumor immunity.
Time of Update: 2020-09-24
Long non-coding RNA (lncRNA) is extremely complex in the occurrence and metastasis of various types of cancer. , the detailed molecular mechanism of lncRNA in non-small cell lung cancer (NSCLC) is not uncertain. September 2, 2020
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Cell Death Dis: The small molecular compound AH057 and SGI-1027 inhibit the development of cervical cancer cells.
Time of Update: 2020-09-24
the study identified a variety of candidates for new JAK inhibitors by simulating the screening of the SPECS database, and assessed the anti-tumor effects of these candidate drugs, especially on CC cell line.
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Cell Res: Zeng Musan/Bai Fan/Zhong Xi collaborated to discover the "skin-immunity" dual
Time of Update: 2020-09-24
, and identify a unique "skin-immune" dual characteristic tumor cell subgroup. , the study was published online in cell Research under the title: Single-cell transcriptomic analysis of the interplay between tum cells, virus, and the microenvironment
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Cell Death Dis: Radish seed extract Sulforaphene may be a new treatment for esophageal cancer.
Time of Update: 2020-09-24
SCD and CDH3 can promote the metastasis of esophageal cancer by activating the Wnt signaling pathway, while the last two genes are involved in the positive feedback loop of GED45B-MAP2K3-p38-p53, thereby inhibiting the growth of esophageal cancer.
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Nature: Scientists find key to 'stopping' cancer cells - TRIM37 or cell division 'inverter'
Time of Update: 2020-09-24
Cells divide all the time in the body, and uncontrolled errors in the process can contribute to genetic errors and may continue to develop into cancer cells. since cancer cells were discovered more than 100 years ago, scientists have been
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Cell Death Dis: Powerful herbal formula SH003 activates the autophagy cell death process for stomach cancer.
Time of Update: 2020-09-24
addition, these results show that in hypoxia, SH003-induced endocystic network stress response can regulate the autophagy cell death process induced by BNIP3 by inhibiting the STAT3-G9a path pathline.
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Cell Death Differ: EZH2 R342 methylation modification promotes breast cancer metastasis.
Time of Update: 2020-09-24
researchers also found that meR342-EZH2 can lead to lower levels of target gene expression in EZH2 and improve EMT processes, cell invasion, and tumor metastasis in breast cancer cells.
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Nature: Finally know why cancer cells are so "big", it turns out that they are more "grabbing food"
Time of Update: 2020-09-23
further analysis, the researchers determined that the high expression of SLC43A2 in tumors was associated with a decrease in T-cell immune response in cancer patients.
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Nat Commun: HIF-1 alpha and HIF-2 alpha play the opposite regulatory role in renal transparent cell carcinoma.
Time of Update: 2020-09-23
Although studies on ccRCC have shown that HIF-1 alpha is an inhibitor of invasive tumor behavior and HIF-2 alpha has a promoting effect, it is not clear what role the two play in tumor development.
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Cell Death Differ: AQP1 may be used as an indicator for predicting the sensitivity of cycloviral drugs in breast cancer patients.
Time of Update: 2020-09-23
researchers also found that miR-320a-3p can reduce the chemotherapy sensitivity of cyclopenoids by inhibiting the expression of AQP1.
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Cell Death Dis: EphA2 Y772 phosphate is essential for the development of nasopharyngeal cancer.
Time of Update: 2020-09-23
in summary, the study showed that EphA2 protein 772th tyrosine phosphate is essential for the growth of EphA2-dependent nasopharyngeal cancer cells, a process achieved by activating the Shp2/Erk-1/2 signaling path.
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Cell Death Dis:lncRNA LRRC75A-AS1 promotes the development of triple negative breast cancer.
Time of Update: 2020-09-23
Reescue rescue experiment also showed that LRRC75A-AS1 in TNBC was able to promote cell proliferation, invasion, and EMT processes by targeting miR-380-3p/BAALC pathps.
