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A review of the research progress of leukemia stem cells in acute T lymphoblastic leukemia

 Time of Update: 2022-06-18

with humanized NOTCH1 mAb decreased NOTCH1(mutated) T- The LSC survival rate and self-renewal ability of ALL LSC-transplanted mice, and lead to the depletion of CD34(+)CD2(+)CD7(+) cells with continuous engraftment ability, provide a new direction
The difference between Tianzhu yellow and synthetic bamboo yellow, the comparison table of the characteristics of the chaotic variety of Panax notoginseng

 Time of Update: 2022-06-17

Tianzhu YellowTianzhuhuang, also known as bamboo yellow, was once included in the 1977 edition of the pharmacopoeia under the name of bamboo yellow.
X-ray examination showed spinal bamboo-like changes, what is the disease?

 Time of Update: 2022-06-16

_ Link to previous article: Which joint is most commonly affected by rheumatoid arthritis?
Stem cells reproduce a new controversy?

 Time of Update: 2022-06-07

The researchers found severe lipofuscin accumulation in more than 90% of neurons in the amygdala region by post-mortem tissue from healthy adults (50-86 years old), but there were still 3.
Cell Stem Cell Human-derived pluripotent stem cells remodel the midbrain dopamine pathway

 Time of Update: 2022-06-05

. A number of clinical works have pointed out that this therapy can significantly alleviate the motor dysfunction in patients with long-term Parkinson's disease [3
Targeting cancer stem cell antigens: novel dual antibodies have great potential

 Time of Update: 2022-05-31

In conclusion, the research and development idea of MCLA-158 is extremely novel, focusing on the antigen targets of cancer stem cells, constructing double antibodies with EGFR and HER3, and screening candidate double antibody molecules through tumor organoids .
Ruijian Pharmaceutical "Qingqi" received the first IND acceptance of pluripotent stem cell-derived drug in the field of Parkinson's disease in China

 Time of Update: 2022-05-30

As the world's first high-tech pharmaceutical company focusing on the research of high-efficiency chemical small molecules to induce functional cell regeneration, Ruijian Medicine has established an induced pluripotent stem cell (iPSC) product development platform based on regenerative medicine .
Bamboo chrysanthemum A

 Time of Update: 2022-05-29

Thin layer plate silica gel G plateEluent petroleum ether - ethyl acetate - methanol - acetic acid (8:5:0.
Breaking through the limitations of stem cell therapy and taking stock of the multiple application directions of CD117 targets

 Time of Update: 2022-05-28

antibody product candidate JSP191. Data on the latest efficacy, safety and pharmacokinetics from a central phase 1 clinical trial . ▲ Image source: Jasper's official
Venus-Neo expandable biological stem valve successfully completed the world's first clinical application

 Time of Update: 2022-05-23

Medical College of Huazhong University of Science and Technology ("Wuhan Union") . After Venus-Vitae and Venus-PowerX, Venus-Vitae is another new generation of stem valve product that has
New research in the sub-journal of Nature reveals the regulatory mechanism of hematopoietic stem cells entering the bone marrow for the first time

 Time of Update: 2022-05-22

▲The huge difference between hematopoietic stem cells and bone marrow microenvironment between embryonic and adulthood (Image source: Reference [1])The experimental results revealed that the bone artery is the key microenvironmental cell in the embryonic stage .
Bmc Infect Dis: Systemic Antifungal Strategies in Allogeneic Hematopoietic Stem Cell Recipients: Analysis of a Cross-sectional Observational AFHEM Study

 Time of Update: 2022-05-21

The literature reported here analyzes a cross-sectional observational AFHEM study to describe the use of antifungal drugs in real-world clinical practice in alloHSCT recipients hospitalized in a French hematology ward .
The research team made a major breakthrough in the induced pluripotent stem cell technology published in "Nature" today!

 Time of Update: 2022-05-21

>This time, following "nuclear transfer" and "transcription factor induction", Chinese scientists proposed a new technology for the preparation of induced human pluripotent stem cells: chemical reprogramming .
J Clin Oncol: Efficacy and safety of nasoprilumab in the treatment of hematopoietic stem cell transplantation-associated thrombotic microangiopathy

 Time of Update: 2022-05-21

This study is a single-arm, open-label, flight trial to evaluate the safety and efficacy of nasoprilumab in adult patients with HSCT-TMA .
Green Bamboo Bio uses Lonza GS Xceed(R) gene expression system to develop recombinant shingles vaccine and bispecific antibody

 Time of Update: 2022-05-20

transcriptional activity . >https://pharma. lonza. com/offerings/specialized-capabilities/expressions-technologies/GS-piggyBac >
Zeng Yi's group established a new method for in vitro long-term expansion of pancreatic islet organoids based on Procr stem cells

 Time of Update: 2022-05-18

This work establishes a technical method for isolating Procr stem cells from mouse islets and long-term expansion of mouse islet organoids in vitro .
The regulatory role of small GTPases-Rab13 in breast cancer stem cells

 Time of Update: 2022-05-18

This work has identified a key mechanism that interrupts the interaction between cancer stem cells and their microenvironment.
Injectable stem cell assembly for cartilage regeneration

 Time of Update: 2022-05-17

They established an injectable hybrid inorganic (IHI) nanoscaffold-templated stem cell assembly and applied it to the regeneration of critical-size cartilage defects .
Leukemia: Prognosis for early relapse after autologous stem cell transplantation in Hodgkin lymphoma patients has improved in recent years

 Time of Update: 2022-05-17

C Cumulative incidence of checkpoint inhibitor (CPI) use according to year of relapse in adult patients relapsed after autologous sct in patients with relapsed/refractory classic HL following first-line therapy .
"Cell Stem Cell" artificially cultivates self-sustaining muscle cells

 Time of Update: 2022-05-17

In a second set of experiments, the researchers transplanted muscle stem cells into genetically engineered mice with mutations in the gene for muscular dystrophy, resulting in Duchenne muscular dystrophy, a mouse and human Muscle wasting disease .

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