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with supramolecular macrocycles as carbon sources are used for high...
Time of Update: 2021-08-05
It is slow Solution Day beneficial tight Zhang of the energy source to be seeking and loop environment pollution dyeing , etc. asked questions , made development of new type can be re- born energy
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JACS: supramolecular organic framework based on Schiff base macrocycles
Time of Update: 2018-10-29
The adsorption separation of mixed gas depends on the difference of adsorption capacity of solid adsorbent for each component The efficiency of this separation technology mainly depends on the perform
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The macrocyclic compound DOTA is generally combined with a variety of groups
Time of Update: 2022-09-14
Macrocyclic compounds are still used in daily life, generally combined with a variety of groups, today mainly from Dota-butyne, DOTA-azide, DOTA-NHS ester, DOTA-SH, DOTA-MeTz, DOTA-Maleimide, DOTA-(COOt-Bu)3 and other related physical data for collation and explanation.
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Innovative drugs: the macrocyclic structure is not only a breakthrough patent, but also a problem-solving
Time of Update: 2022-03-08
? Activity example In the development process of BACE inhibitor, some researchers have studied and analyzed the protein, and designed a macrocyclic ring structure based on this, and the activity has been significantly improved, as shown in the figure below .
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A two-dimensional supramolecular polymer based on organoplatinum metal macrocycle
Time of Update: 2021-06-22
Recently, the research group of Professor Yang Haibo of East China Normal University, the research group of Professor Jin Wen of Donghua University and the research group of Professor Philip Gale of the University of Sydney, Australia have developed a two-dimensional supramolecular polymer based on organoplatinum metal macrocycles.
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Chiral Separations Using the Macrocyclic Antibiotics in Capillary Electrophoresis
Time of Update: 2021-01-05
Although capillary electrophoresis (CE) is a relatively new technique as compared to high-performance liquid chromatography (HPLC) or thin-layer chromatography (TLC), it has increased significantly in popularity over the last decade.
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Use of Macrocyclic Antibiotics as the Chiral Selectors in Capillary Electrophoresis
Time of Update: 2020-12-30
Macrocyclic antibiotics, especially vancomycin, represent a class of versatile chiral selectors for enantioseparations by capillary electrophoresis (CE).
In this chapter, we describe the protocol for performing CE enantioseparations with vancomycin as the chiral selector.
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Enantioseparations by High-Performance Liquid Chromatography Using Macrocyclic Glycopeptide-Based Chiral Stationary Phases: An Overview
Time of Update: 2020-12-24
Since their introduction by Armstrong in 1994, macrocyclic antibiotic-based chiral stationary phases have proven their applicabilityfor the chiral resolution of various types of racemates.
These are the major reasons for the use of macrocyclic antibiotic-based stationaryphases in HPLC enantioseparations.
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Enantiomeric Separations by HPLC Using Macrocyclic Glycopeptide-Based Chiral Stationary Phases: An Overview
Time of Update: 2020-12-18
The separation of enantiomers is now accomplished by chiral chromatographic and electrophoretic methods, which includes gas chromatography (GC), high-performance liquid chromatography (HPLC), thin-layer chromatography (TLC), supercritical fluid chromatography (SFC), capillary electrochromatography (CEC), and capillary electrophoresis (CE).
The search for more effective and universal chiral stationary phases (CSPs) for HPLC is an ongoing and challenging topic for separation scientists.
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Hantzsch Based Macrocyclization Approach for the Synthesis of Thiazole Containing Cyclopeptides
Time of Update: 2020-12-12
An innovative macrocyclization approach via high-yielding solid-phase intramolecular thioalkylation reaction is described. The reaction ofS -nucleophiles with newly generated N-terminal 4-chloromethy
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Macrocyclic Peptides with Endo Aryl-Aryl and Aryl-Alkyl Ether Bonds
Time of Update: 2020-12-01
Ring closure via the formation of aryl-aryl (type A) (18 ) and aryl-alkyl ether bonds (type B, Fig. 1 ) (19 ) by way of intramolecualr SN Ar reaction (20 ) will be the focus of this chapter.
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Construction of solid-phase molecular machine for four-dimensional information code by thermally activated carbon rich macrocyclic molecular receptor
Time of Update: 2020-02-03
In recent years, carbon rich macrocyclic molecules have attracted great attention due to their special topological structure, band characteristics and photoelectric properties The synthesis of carbon
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Zelaland spent $80 million to acquire the macrocyclic peptide platform
Time of Update: 2019-10-28
Recently, Zealand Pharma, a Danish biomedical company focused on peptide drug research and development, announced that it would buy cycle therapeutics, a Toronto based biotechnology company, for us $8
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JACS: Nuno maulide team 10 steps to complete the synthesis of macrocyclic immunosuppressant fr252921 and its analogues
Time of Update: 2019-09-02
Immunosuppressive drugs have been widely used in the treatment of allograft rejection and autoimmune diseases However, most immunosuppressants have serious side effects and limitations Therefore, in o
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macrocyclic / cage based fluorescent supramolecular polymer and regulation of its luminescent properties
Time of Update: 2018-12-08
Introduction in recent years, fluorescent supramolecular polymer is a hot topic in the field of functional supramolecular polymer research, which benefits from the introduction of fluorescent groups c