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J Clin Anesth: The effect of intravenous lidocaine on the quality of recovery and analgesia after thoracoscopic surgery: a randomized controlled trial

 Time of Update: 2021-04-17

Main resultMain results The main resultsThere was no statistically significant difference in QOR-15 scores between lidocaine group and normal saline group at 24 hours after surgery (lidocaine group: median 117, interquartile range (IQR) 113.
JAMA: The effect of celecoxib combined with FOLFOX standard adjuvant chemotherapy on the disease-free survival rate of colon cancer patients

 Time of Update: 2021-04-17

Recently, researchers investigated the effect of adding celecoxib to the adjuvant chemotherapy regimen of fluorouracil, calcium leucovorin and oxaliplatin (FOLFOX) on the disease-free survival rate of patients with stage III colon cancer .
JCO: The effect of adjuvant chemotherapy on the quality of life of elderly patients with HER2-positive breast cancer

 Time of Update: 2021-04-17

to trastuzumab (T) group and trastuzumab combined chemotherapy group (T+C). Using the Comprehensive Cancer Therapy Functional Assessment Scale (FACT-G), Philadelphia Geriatric Center Morale Scale, Hospital Anxiety and Depression
Am J Gastroenterol: How effective is Buspiron on children with functional abdominal pain?

 Time of Update: 2021-04-17

Recently, researchers conducted a randomized clinical trial to evaluate the efficacy of Buspirone on children's FAP, and the results of the study have been published in Am J Gastroenterol.
Ondexxya quickly reverses the anticoagulant effect of Apixaban or Rivaroxaban!

 Time of Update: 2021-04-17

>UK NHS cost regulators have provided financial support for the Alexion's Ondexxya (andexanet alfa), to reverse the direct factor Xa (FXa) inhibitor apixaban (

JAMA Sub-Journal: The effect of high frequency (10khz) spinal cord stimulation on patients with painful diabetic neuropathy

 Time of Update: 2021-04-17

Based on this, some researchers have studied whether 10khz spinal cord stimulation (SCS) can improve the prognosis of patients with refractory painful diabetic neuropathy (PDN).
NEJM: Sutimlimab is effective in treating cold agglutinin disease

 Time of Update: 2021-04-17

Sutimlimab can rapidly improve the symptoms of hemolysis in patients with cold agglutinin disease by selectively inhibiting the upstream target of the classical complement pathway , increase hemoglobin levels and reduce fatigue.
Lancet Neurology: Safety and effectiveness of enhanced blood pressure reduction after successful

 Time of Update: 2021-04-17

There is no evidence that the intensive strategy of reducing the systolic blood pressure to 100-129mmHg in patients with acute ischemic stroke within 24-36 hours after successful endovascular treatment has any effect on reducing imaging intraparenchymal bleeding.
Gut: Existing imaging methods are still not effective in screening for pancreatic cancer in time!

 Time of Update: 2021-04-16

In total, 366 individuals were recruited, including 201 non-mutant relatives of familial pancreatic cancer (FPC) patients and 165 PDAC susceptible gene mutation carriers .
Field research and community group buying: almost no money in the short term, and new technologies have limited temporary effects

 Time of Update: 2021-04-16

Compared with Internet companies doing community group purchases, the main daily fresh food business approach is to purchase directly from the first-level wholesalers, sort and pack them, and then distribute them to each front warehouse.
The team of Associate Professor Xiaoyan Zhao from the University of Jinan: The effect of ultrasound

 Time of Update: 2021-04-16

. Because of its nutritional value and health benefits, it is welcomed by people all over the world. Ultrasound is an efficient non-heat treatment technology that can regulate the growth, physiological metabolism
J Immunother Cancer: Antibiotics have a significant negative effect on the prognosis of NSCLC patients treated with pembrolizumab!

 Time of Update: 2021-04-16

>In unselected patients with non-small cell lung cancer ( NSCLC
Anesthesiology: The effect of intravenous anesthesia and inhalation anesthesia on postoperative

 Time of Update: 2021-04-16

laparoscopic abdominal surgery for more than 2 hours were randomly assigned to propofol or sevoflurane as the basic drug regimen to maintain general anesthesia, and at least 221 patients were assigned to each group for verification.
Ann Neurol: Nabirone can effectively and safely treat Parkinson's disease patients with non-motor symptoms

 Time of Update: 2021-04-16

A phase II placebo-controlled, double-blind, parallel group, randomized controlled trial investigated Nabilong as a treatment for Parkinson’s disease (PD) non-exercise The effectiveness and safety of symptoms (NMS), research results have been published in Ann Neurol.
JAMA Oncol: Tislelizumab combined with chemotherapy as a first-line treatment for advanced squamous non-small cell lung cancer has a significant effect

 Time of Update: 2021-04-16

In conclusion, in this phase 3 randomized clinical trial, regardless of the expression of PD-L1, for patients with advanced sq NSCLC, the addition of Tislelizumab and IRC to chemotherapy significantly prolonged PFS, higher ORR, and better safety/resistance.
Nature: It is so difficult to investigate rare side effects of COVID vaccine

 Time of Update: 2021-04-16

Hilda Bastian said that because hundreds of millions of people are currently vaccinated against COVID-19, even very rare events-such as severe allergic reactions or blood clots-will start to appear in safety reports.
Lancet Oncol: Active symptom control combined with FOLFOX chemotherapy can effectively prolong

 Time of Update: 2021-04-14

Recently, The Lancet Oncology published a study in which patients with advanced biliary
JAMA Sub-Journal: Cost-effectiveness of opioid addiction treatment

 Time of Update: 2021-04-14

Opioids are psychoactive substances derived from opium poppy or synthetic analogues, such as morphine and heroin
Express | 100% preventive effectiveness, Pfizer's new crown vaccine stimulates a strong immune response in adolescents

 Time of Update: 2021-04-14
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