Editor | Xispleen Tyrosine Kinase (SYK
The detection rate of the new coronavirus mutation gene E484K in six Brazilian states exceeds 50%
Time of Update: 2021-03-27
As of 20:00 local time on March 4th, according to data released by the Brazilian Ministry of Health, Brazil has a total
Study finds low-fatality African swine fever gene type II natural mutation prevalence
Time of Update: 2021-03-24
, the laboratory is carrying out the epidemiological surveillance and monitoring of African swine fever. In etiological studies, it was found that natural variants of African swine fever gene type II with a low fatality rate appeared in some
J Hematol Oncol: KMT2 family gene mutations can predict cancer patients' response to immune checkpoint therapy
Time of Update: 2021-03-20
>The histone-lysine N-methyltransferase 2 (KMT2) family of proteins methylate the lysine 4 at the tail of histone H3 in the important regulatory region
The molecular mechanism by which life responds to unseeded mutations in genes has been cracked
Time of Update: 2021-03-16
of zebrafish, had a small liver ideopaedic when the gene was lowered in different ways, while the liver, a genetic mutation, developed normally. "Knocking out mutants to grow a normal liver suggests that the genetic compensation effect may be at work
Perhaps 5% of autism cases are due to recessive mutations in genes
Time of Update: 2021-03-15
large-scale international study found that recessive mutations in genes cause autism more often than previously thought, with 3 to 5 percent of cases linked.
The study found a new mechanism for coronary heart disease caused by mitochondrial gene mutation
Time of Update: 2021-03-14
professor Guan Minxin of Zhejiang University's Institute of Genetics found that a mutation in mitochondrial genes causes damage to the endotkin of blood vessels, which in turn induces coronary heart disease.
New research reveals new mechanisms to root out cancer cells by bypassing the mutated anti-cancer gene
Time of Update: 2021-03-07
/> That is, mtp53 induces congenital immune signal infusion, alters the production of cytokines, and causes immune escape; Overall, the study found a new mechanism, mtp53, that inhibits cellular autonomy and non-cellular signaling by interfering
Two different point mutations in ABL gene ATP-binding domain conferring primary imatinib resistance in a chronic myeloid leukemia (CML) patient: A case report
Time of Update: 2021-03-07
We established a very sensitive (ASO)PCR to detect mutations in an imatinib-resistant CML patient.
Perhaps 5% of autism cases are due to recessive mutations in genes
Time of Update: 2021-02-25
, June 26 (Xinhua) -- A large-scale international study has found that recessive mutations in genes cause autism more commonly than previously thought, with 3 to 5 percent of cases linked.
New research reveals new mechanisms to root out cancer cells by bypassing the mutated anti-cancer gene
Time of Update: 2021-02-23
TBK1 signal can bypass mtp53, restore immune cell function, activate immune surveillance, and eradicate cancer cells.
PCR Methods for Identification of Point Mutations and Gene Rearrangements
Time of Update: 2021-02-18
The polymerase chain reaction ( PCR ) allows the specific amplifica tion of either RNA orDNA nucleotide sequences ( 1 , 2 ).
The probability of mutation of ovarian cancer anti-cancer gene is clear
Time of Update: 2021-02-09
May 6, Fudan University Affiliated Cancer Hospital held a presentation of ovarian cancer research results, professor Wu Xiaohua led the ovarian cancer research team for many years, the first multi-center ovarian cancer embryo clinical study
A new breakthrough in gene therapy! Successful treatment of mitochondrial gene mutation disease
Time of Update: 2021-02-06
findings suggest that gene repair using programmable nuclease-targeted mtDNA has the potential to become a gene therapy for various genetically-caused heterogeneic mitochondrial diseases.
Mutations in the SLC26A3 gene affect the mechanisms of IBD risk
Time of Update: 2020-12-11
regulate the expression of tightly connected proteins; (4) mechanism, in the colon of DRA knockout mice, RNA binding protein - CUGBP1 and closed protein and E-calcium adhesive protein mRNA binding increased to inhibit the expression
Most cancer genes mutate or cause "bad luck"
Time of Update: 2020-12-07
Nearly two-thirds of cancer gene mutations can be attributed to random errors in DNA (deoxyrucleic acid) replication in healthy cells during division, rather than genetic or environmental factors, according to a new study published Wednesday in .
Flanking Mutator (Mu) Transposons and Thereby Facilitate Gene Cloning
Time of Update: 2020-11-08
DLA-454, which combines DLA with 454 pyrosequencing, permits the efficient amplification and sequencing ofMu flanking regions in a high-throughput manner.
J Clin Oncol: Breast cancer patients with PALB2 embryo mutations can also benefit from PARPi treatment
Time of Update: 2020-11-06
recruit MVC patients who carry HR-related gene germ line mutations (queue 1) other than BRCA1/2, or THOSE-related gene (including BRCA1/2) system mutations (queue 2).
PNAS: Scientists have revealed the difference between pathogenic gene mutations and benign gene mutations
Time of Update: 2020-11-04
gene variants. , the researchers identified features associated with pathogenic and benign mutations that may reveal the effects of mutations at the molecular level. researcher Professor Dennis Lal said the study could provide a powerful
