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What? Automated microscopy can also do multiplex ddPCR to screen for cancer-related point mutations
Time of Update: 2022-12-29
Figure 7 Microdroplet multicolor fluorescence overlay shooting and nucleic acid concentration analysis Table 2 Statistics for calculating DNA concentrations at different targets By using 4-plex ddPCR combined with the Lionheart automated microscopic imaging platform, the excellent experimental data also demonstrate the high sensitivity of this technology, and also demonstrate the potential of its application in cancer screening.
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Detection of host cell residual DNA, ddPCR has many benefits [new product recommendation]
Time of Update: 2021-08-10
Compared with real-time quantitative PCR technology, the advantage of using droplet digital PCR (ddPCR) technology and premix is that the DNA purification step can be skipped and the residual DNA of the host cell can be directly determined .
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Oncologists talk about the clinical application of ddPCR technology
Time of Update: 2021-08-09
Researchers used ddPCR-based liquid biopsy analysis to track ESR1 mutations associated with endocrine therapy resistance .
Although this research is still in progress, preliminary results show that ddPCR technology can quickly detect the presence of ESR1 mutations .
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Scientists focus on the role of ddPCR technology in blood disease monitoring
Time of Update: 2021-08-09
RT-qPCRIn monitoring whether patients with chronic myeloid leukemia (CML) respond to tyrosine kinase inhibitors, detecting the level of the BCR-ABL1 fusion transcript is an effective method .
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Scientists prove the value of ddPCR in quantitative cancer markers
Time of Update: 2021-08-08
Nell, a researcher at Leiden University Medical Center in the Netherlands, has developed a new method that can absolutely quantify the amount, density, and allele specificity of DNA methylation .
Nell combined methylation-sensitive restriction enzymes with ddPCR technology to develop a bisulfite-independent method to quantify epigenetic markers .
