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Certain clinicopathological and molecular predictors in combination with PD-L1 expression can help
Time of Update: 2023-01-05
(If you need the original text, you can add the editor WeChat yxj_oncology to get) Scan the QR code above to get more cutting-edge information1J Natl Cancer Inst: Certain clinicopathological and molecular predictors in combination with PD-L1 expression can help select the most appropriate IO-based first-line therapy for patients with advanced non-small cell lung cancer▎ Clinical problems: immunotherapy (IO) Many NSCLC patients do not benefit well.
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PD-1 monotherapy has progressed, and combination drugs should be carefully selected
Time of Update: 2022-03-07
The synergistic effect of immunotherapy and chemotherapy In the second-line treatment of advanced lung cancer, the general patient's disease progresses after platinum-containing chemotherapy, and the detection of EGFR and ALK driver gene mutations is negative, and immune monotherapy can be used, such as nivolio Monoclonal antibody, pembrolizumab, etc.
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The clinical study on the functional cure of PD-L1 antibody ASC22 hepatitis B was selected
Time of Update: 2021-12-02
(Hong Kong Stock Exchange code: 1672) today announced its PD-L1 antibody ASC22 (Envolimab) for hepatitis B function The phase IIa and phase IIb clinical studies of sexual cure were selected for the 2021 American Association for the Study of Liver Diseases (AASLD) Annual Meeting (The Liver Meeting® 2021) "The Best Abstract Collection-Viral Hepatitis" .
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MOF regulates Pd to improve catalytic activity and selectivity
Time of Update: 2021-06-22
How to rationally regulate the physical and chemical properties of the surface of the metal catalytic site, thereby improving the interaction between it and the substrate is one of the keys to achieving high-efficiency catalysis .
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Kangfang Bio-PD-1 submitted the US listing application: being selected for RTOR, faster than priority review
Time of Update: 2021-06-05
In addition, BeiGene and Novartis announced that they will submit PD-1 antibody marketing applications (esophageal squamous cell carcinoma and non-small cell lung cancer) to the FDA within the year.
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Angelw: Pd / Cu co catalysis for selective heck Sonogashira coupling
Time of Update: 2019-12-01
Because of their special stability, reactivity and biological activity, organofluorine compounds have been widely used in pharmaceutical chemistry and agricultural chemistry On the other hand, chiral
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: Pd / NHC precisely unlocks the selective activation of o-carborane B (3,6) - H
Time of Update: 2019-11-26
Lead carborane is a kind of boron carbon molecular cluster with three-dimensional aromaticity It has an important application prospect in the fields of high temperature resistant materials, luminescen
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PD catalyzed para selective alkylation of electron deficient aromatic hydrocarbons
Time of Update: 2018-05-06
Aromatics are widely used in bioactive natural products, drugs and functional materials In the study of aromatics functionalization, site selective alkylation is an important topic Friedel crafts alky