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PNAS: Telomere-lengthening molecules that help cancer cells live forever and can be used as cancer treatment targets
Time of Update: 2023-02-03
Overexpression of TERRA leads to ALT cell deathCurrently, the research team is identifying proteins that activate or inhibit TERRA expression and plans to develop small molecule drugs that target these proteins for preclinical trials against ALT cancer cells.
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Cell sub-issue: Development of a live-in attenuated DNA virus vaccine against DNA virus infection
Time of Update: 2023-01-05
The authors say that developing a method that can quickly and easily produce a live attenuated virus with replication defects will accelerate vaccine development against diseases caused by DNA viruses.
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The next generation of mitochondrial imaging tools in living and fixed cells – the MitoBrilliant fluorescent probe
Time of Update: 2023-01-01
Fluorescent probes enable high-precision, sensitive, specific, and long-lasting labeling of mitochondria and are critical for a range of demanding scientific and biomedical applications such as high-content screening, flow cytometry, and super-resolution microscopy.
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Nature Immunology: Identification of long-lived plasma cell taxa
Time of Update: 2022-11-14
On October 31, 2022, the Qi Hai Research Group of the Institute of Immunology, School of Medicine, Tsinghua University, and Wang Jianbin's Research Group, School of Life Sciences, Tsinghua University
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【Cell Storage】Cell technology may help humans live to 120 years old!
Time of Update: 2022-11-04
How old is a person's normal life expectancy?American microbiologist Leonardo ▪ Hayvlik found that human embryonic lung fibroblasts can only divide about 50 times, and then appear malformed, stop dividing, and die.
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"Neuron" observes living human brain cells in a petri dish and learns to play table tennis
Time of Update: 2022-10-20
While researchers have been able to mount neurons on multi-electrode arrays and read their activity, this is the first time cells have been stimulated in a structured and meaningful way.
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Explore how living cells regulate the growth of organelles
Time of Update: 2022-10-03
She plans to use mathematical modeling and simulation to quantitatively analyze the mechanisms used by cells to maintain competing structures in shared pools.
She plans to use mathematical modeling and simulation to quantitatively analyze the mechanisms used by cells to maintain competing structures in shared pools.
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ESMO Live Strikes New Discovery! Psychiatric disorders are positively associated with the risk of death from testicular germ cell carcinoma
Time of Update: 2022-10-03
In the case group, investigators used cohort study design and Cox regression to assess the risk ratio (HR) and 95% CI associated with a history of psychiatric illness and all-cause and TGCC-specific mortality.
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MIT develops new tool "Cell Rover": Tiny Wireless Real-Time Monitoring of Living Cells
Time of Update: 2022-10-01
" ” Researchers at MIT Media Lab have designed a miniature antenna that operates wirelessly inside living cells, opening up possibilities for medical diagnosis and treatment, as well as other scientific processes, because of the potential to monitor and even guide cellular activity in real time.
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ESMO Live Direct Strike Double Free or Triple? Choice of combination therapy regimens for Merkel cell carcinoma
Time of Update: 2022-09-21
The efficacy of navuliyumab + ipicumab ± stereotactic radiation (SBRT) in the treatment of advanced Merkel cell carcinoma was announced at the ESMO conference.
The efficacy of navuliyumab + ipicumab ± stereotactic radiation (SBRT) in the treatment of advanced Merkel cell carcinoma was announced at the ESMO conference.
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JAX Jackson Lab Live Trailer: Mouse Models Power T Cell Research
Time of Update: 2022-09-14
There are about 300 billion T cells in an adult's body, and that number has amply demonstrated the importance of T cells as a very large class of immune cells that lose T cells that our body will not
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Molecular-level processing system for highly targeted and robust digital information within living cells
Time of Update: 2022-09-14
Thesis link: As a possible storage medium, DNA has the advantages of strong stability, high storage density and low maintenance cost, and the digital information is encoded and written to the DNA sequence, which can realize the molecular level storage of data.
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The human body is like a kingdom, with 40-60 trillion cells working and living in their own right
Time of Update: 2022-09-14
The treatment of this interstitial lung disease is mainly anti-rheumatic therapy, and the drugs are used to vigorously suppress the "rebellious" immune cells, using hormones and immunosuppressive drugs, these rebellious cells, no matter how much they usually contribute, as long as they attack their own cells, they must be ruthlessly cleared or suppressed, otherwise they may endanger the organs of the whole body and cause damage.
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Application of the live-cell imager Holomonitor M4 in holographic dynamic monitoring of organoid growth and migration
Time of Update: 2022-09-14
Case 1Subpopulations of Organoid-Forming Cells Have Different Motility Oropharyngeal squamous cell carcinoma (OPSCC) stem cells have the ability to self-renew and differentiate into tumor heterogeneous three-dimensional structures.
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Scientists develop live-cell transcriptome sequencing technology
Time of Update: 2022-09-01
Existing methods are either limited by the dynamic characterization of cell morphology or a few genes, or rely on a variety of assumptions in quasi-temporal analysis that may not be satisfied in actual cell systems, and currently cannot directly measure cell-wide transcriptome state changes .