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Layout acceleration! A brief analysis of the current situation and trend of gene therapy industry in China
Time of Update: 2021-01-19
of the biopharmaceutical industry. platform for the country's first set of shared laboratories, shared CDMO workshop, shared clinical center as one of the industrial support system. Industrial Park will be completed in 2022 and put into operation in 2023
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Tools for Expressing Foreign Genes in Plants
Time of Update: 2021-01-19
The spectrum of plant species amenable to transformation is continuously widening.
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Analysis of Gene Expression in Transgenic Plants
Time of Update: 2021-01-19
Common methods of transcript analysis by Northern and dot-blot hybridizations using nonradioactive probing methods are described.
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PCR Cloning of Coat Protein Genes
Time of Update: 2021-01-19
The polymerase chain reaction ( PCR ) is used to amplifyDNA between two oligonucleotide primers, of which one is complimentary to a sequence on the (+)-strand and the other to a downstream sequence on the (−)-strand.
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Engineering High Yields of Secondary Metabolites in Rubia Cell Cultures Through Transformation with Rol Genes
Time of Update: 2021-01-18
cells with therol genes as an example of metabolic engineering of secondary metabolites.
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Targeted Mutagenesis for Functional Analysis of Gene Duplication in Legumes
Time of Update: 2021-01-18
Here we describe a method for engineering zinc-finger nucleases (ZFNs) for the purpose of creating targeted mutations in the paleopolyploid soybean genome.
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Stable Transformation of Medicago truncatula cv. Jemalong for Gene Analysis Using Agrobacterium tumefaciens
Time of Update: 2021-01-18
Leaf explants can be used for the transformation of the embryonic stem cells to produce the transgenic somatic embryos for regeneration.
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Identification of Regulatory Protein Genes Involved in Alkaloid Biosynthesis Using a Transient RNAi System
Time of Update: 2021-01-18
We report here the use of transient RNAi to isolate regulatory factor genes involved in isoquinoline alkaloid biosynthesis inCoptis japonica protoplasts.
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Characterization of Rice Genes Using a Heterologous Full-Length cDNA Expression System
Time of Update: 2021-01-18
This system was applied to high-throughput analysis of rice genes through heterologous expression inArabidopsis (rice FOXArabidopsis lines).
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Lilly has teamed up with Precision for gene therapy for Duchy's muscular dystrophy
Time of Update: 2021-01-17
not currently have an effective treatment, creating drugs with transformational potential by working closely with the Precision scientific team and using their platform to develop and deliver drugs that target untreated genetic diseases. , of course
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In planta Expression of Oomycete and Fungal Genes
Time of Update: 2021-01-17
These assays allow rapid functional expression of pathogen genes in plants and can be used in high-throughput screens.
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Using Natural Allelic Diversity to Evaluate Gene Function
Time of Update: 2021-01-17
Association approaches in plants can provide very high resolution and can evaluate a wide range of alleles rapidly.
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The Chen Gong team at Jinan University used neurogenetic gene therapy to bring new hope to patients with spinal cord injuries
Time of Update: 2021-01-17
/> this is consistent with the results of transdifferentiation in the brain, showing that different combinations of transcription factors can be used to control the transformed neuron subsype and its proportions, so as to carry out nerve regeneration and repair
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The Quantitative Real-Time Polymerase Chain Reaction for the Analysis of Plant Gene Expression
Time of Update: 2021-01-17
The quantitative real-time polymerase chain reaction is used to simultaneously amplify and quantify a targetedDNA molecule.
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Systems Approaches to Unraveling Plant Metabolism: Identifying Biosynthetic Genes of Secondary Metabolic Pathways
Time of Update: 2021-01-17
The diversity of useful compounds produced by plant secondary metabolism has stimulated broad systems biology approaches to identify the genes involved in their biosynthesis. Systems biology studies in non-model plants pose interesting
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BRAIN: The network controllability and regional gene expression differences behind Parkinson's disease hallucinations
Time of Update: 2021-01-17
to solve this problem, this study looked at changes in structural connectivity associated with Parkinson's disease accompanied by visual hallucinations, as well as tissue and gene expression characteristics in the affected areas of the network.
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Gene Transfer into Plant Protoplasts by Electroporation
Time of Update: 2021-01-17
Introduction of foreign genes into plant cells can be achieved by a variety of methods, including direct transfer into protoplasts using chemical ( 1 – 3 ; see also Chapter 7 , this volume
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FDA grants Zenotuzumab 'fast track qualification' to treat NRG1 gene fusion tumors
Time of Update: 2021-01-16
Merus is currently recruiting patients for Phase I/II clinical trials aimed at evaluating the effectiveness of Zenocutuzumab's single-drug treatment of pancreatic cancer and other solid tumors that are fusion of the NRG1 gene.
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Gene Tektronox anti-TIGIT antibody Tiragolumab has been identified by the FDA as a breakthrough therapy
Time of Update: 2021-01-16
of THE CITYSCAPE, published at the 2020 annual meeting of the American Society of Clinical Oncology (ASCO), showed an improvement in the overall remission rate (ORR of 37% vs. 21% of the risk of disease deterioration or death (no progression survival PFS
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Nat Commun: What are the risk genes for skin cancer?
Time of Update: 2021-01-16
to track the lifetime risk of three types of skin cancer, the researchers also developed a second age-independent disease score, called DRSA.