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[Nature sub-issue] Marine bacteria make "anti-cancer molecules", and scientists understand the mystery for the first time!
Time of Update: 2022-04-28
Co-author Bradley Moore, Distinguished Professor of Scripps Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, said: "Now that scientists understand how this enzyme makes the salinosporamide A 'warhead', this discovery could be used in the future to harness the enzyme to Produce other types of salinosporamides that attack not only cancer but also diseases of the immune system and infections caused by parasites .
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Cell Sub-Journal: This molecule makes the adult hippocampus nerve regeneration firstly strong and then weak, and finally "lying down"
Time of Update: 2021-06-30
This indicates that during the transition from adolescence to adulthood, the differentiation of neural stem cells proliferating in the hippocampus gradually decreases, gaining the ability to restore rest and maintaining the stability of the number of neural stem cells .
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Sharks use unique molecules to make green
Time of Update: 2021-03-16
are probably the most famous fluorescent marine organisms that emit bright greens and blues, and scientists use their proteins to track proteins in cells and even create cats that glow in the dark.
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Protein degradation, other inhibition: small molecule drug make-up
Time of Update: 2021-01-01
analysis rational protein degradation and other structure inhibitors are now small molecules of new drug research and development of pre-drug technology.
these patients have been treated with CDK-4/6 inhibitors and a variety of ER antagonists, including other clinical protein degradation drugs.
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The molecules produced by the blood after exercise make the brain younger.
Time of Update: 2020-09-06
Recently, Science magazine, an internationally renowned journal, published an article entitled "Blood factors transfer effects of exercise on neurogenesis and cognition to the old brain".
reported that a cytokine produced in the blood after exercise can promote nerve regeneration in the elderly brain and improve cognitive ability.
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Science: How do you make your brain think it's healthy? It's ok to supplement this molecule.
Time of Update: 2020-07-17
however, the researchers say that just increasing the level of gpld1 produced by the liver of mice has the same benefit to the brain as long-term exercise.