Looking at the biology of the new coronavirus from the perspective of Crisp(r) gene editing technology | Cell Press
Time of Update: 2021-03-25
You can find the submission policy of COVID-19-related papers, as well as the papers on the epidemic and virus published in the journals of Cell Press on the resource center page.
Nature Cell Biology: Single cell analysis reveals the mechanism of human prostate cancer progression
Time of Update: 2021-03-25
Recently, researchers have analyzed the transcriptomes of 36,424 single cells from 13 types of prostate tumors and identified epithelial cells to explain the underlying disease invasion mechanism.
Guangzhou Institute of Biology, Chinese Academy of Sciences discovers a new switch that regulates the pluripotency of embryonic stem cells
Time of Update: 2021-03-18
The construction of YTH domain mutants and Mettl3 knockout cell lines proved that the above process is m 6 A dependent, indicating that RNA m 6 A has the function of regulating chromatin.
BMC | SpringerOpen | Not to be missed is a collection of cell biology studies
Time of Update: 2021-03-15
focusing on cell death, epigenetics, stem cell therapy and cell signaling... This thematic series of state-of-the-science publications covers cutting-edge developments in the field of oncology and pathology with reference to diagnostic
Histoprotein modification regulates mRNA shearing to determine the fate of embryonic stem cells
Time of Update: 2021-03-13
, it is revealed that histone modification can participate in the regulation of ESC directional differentiation by regulating variable shearing of cell cycle-related transcription factors or path path genes.
Isolation of Cell Wall Proteins from Medicago sativa Stems
Time of Update: 2021-03-10
that contain phenolic compounds. This chapter discusses protein extraction from cell walls and presents a specific method for the isolation of proteins fromMedicago sativa stem cell walls. The method includes cell disruption by grinding
The Guangzhou Institute of Biology of the Chinese Academy of Sciences has developed a 5G version
Time of Update: 2021-02-24
team led by Yan Tingqing, a researcher at the Guangzhou Institute of Biomedicine and Health of the Chinese Academy of Sciences, developed a new method of high-efficiency reprogramming using 7 factors instead of traditional 4 factors (OKSM
Preparation of Cell-Wall Fractions from Mycobacteria
Time of Update: 2021-02-21
Research extending over 50 years has implicated various components of the mycobacterial cell-wall matrix in many host responses associated with tuberculosis and other mycobacterioses ( 1 ). The observed responses originally
Flow Cytometry in Environmental Microbiology: A Rapid Approach for the Isolation of Single Cells for Advanced Molecular Biology Analysis
Time of Update: 2021-02-16
We describe here the combination of fluorescent in situ hybridization and cell sorting for the detection and isolation of Candidate Division TM7 bacteria from an enriched soil sample.
To kill cancer cells, destroy their "protective walls" first.
Time of Update: 2021-02-15
Dr Francis Musai, of the University of Birmingham, one of the report's authors, said existing immunotherapy often failed to kill cancer cells effectively because the immune system often failed to reach them.
Biology Open: Stem cell research helps treat non-alcoholic fatty liver disease
Time of Update: 2021-02-11
article in the journal Biology Open attests to the strong heterogeneity of cell line in terms of gene expression and lipid drop form. believe this is due to excessive metabolic networks during the development of the disease. , as the team
Extraction of Cell Wall-Bound Teichoic Acids and Surface Proteins from Listeria monocytogenes
Time of Update: 2021-01-30
In this chapter, we describe methods for the extraction and analysis of (i) WTAs, (ii) covalently, and (iii) non-covalently cell wall-bound surface proteins from the Gram-positive pathogenListeria monocytogenes .
Acta Neuropathologica: Transparent cell meningioma is defined as a highly different DNA methylation spectrum and SMARCE1 mutation
Time of Update: 2021-01-15
In the study, the team described a molecularly different tumor substation, n-31, which was originally found in 3,093 meningoma queues through genome-wide DNA methylation screening, most of which were histologically diagnosed as transparent cell meningomas.
Selected Simple Methods of Plant Cell Wall Histochemistry and Staining for Light Microscopy
Time of Update: 2021-01-14
Histochemical methods allow for identification and localization of various components within the tissue.
Such information on the spatial heterogeneity is not available with biochemical methods.
Characterization of the Plant Cell Wall Proteome Using High-Throughput Screens
Time of Update: 2021-01-13
The approaches are orthogonal and collectively provide a powerful suite of approaches to complement more commonly used strategies to isolate plant cell wall-associated proteins.
Determination of the permeability of plant cells (mass wall separation method)
Time of Update: 2021-01-07
The cell volume in the initial mass wall separation state is slightly smaller than when the absorbent is saturated, so the permeability potential of cell fluid concentration and penetration is slightly lower than that of absorbent saturation.
Preparation and Use of Tethered Ligands as Biomaterials and Tools for Cell Biology
Time of Update: 2020-12-09
These studies have had important applications in the creation of antithrombogenic surfaces for blood contact, affinity chromatography, and tissue growth and regeneration.
Resin Embedding, Sectioning, and Immunocytochemical Analyses of Plant Cell Walls in Hard Tissues
Time of Update: 2020-11-21
) and carbohydrate-binding module (CBM) probes and their detection by immunofluorescence microscopy. Here we describe resin embedding, sectioning, and in situ chemical and enzymatic cell wall disassembly and their use with immunocytochemical analyses as a means to unravel the complexity of cell wall molecular architecture in hard tissues and seeds.
Monoclonal Antibodies, Carbohydrate-Binding Modules, and the Detection of Polysaccharides in Plant Cell Walls
Time of Update: 2020-11-20
We provide an account of methods that can be used to detect cell wall polysaccharide structures (epitopes) in plant materials and also describe treatments that can provide information on the masking of sets of polysaccharides that may prevent detection.
Measuring In Vitro Extensibility of Growing Plant Cell Walls
Time of Update: 2020-11-19
This article summarizes the theory and practical aspects of measuring cell wall properties by four different extensometer techniques and how the results of these methods relate to the concept and ideal measurement of cell wall