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Nature Deng Hongkui's team published major research results - chemical small molecules induce human adult...
Time of Update: 2022-05-11
On April 13, 2022, the research team of Deng Hongkui from the School of Life Sciences of Peking University and the Joint Center for Life Sciences published a research paper titled "Chemical reprogramming of human somatic cells to pluripotent stem cells" online in the international academic journal Nature.
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The world's first oral small molecule PD-(L)1 human test data disclosure
Time of Update: 2021-12-04
According to the previous public information of Betta Pharmaceuticals' application for Hong Kong stocks, BPI-371153 is an innovative, oral small molecule PD-L1 inhibitor that can achieve an anti-tumor immune response comparable to anti-PD-L1 antibodies in preclinical studies .
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Research has discovered a molecule that can stimulate human muscle growth
Time of Update: 2021-08-13
In a randomized controlled study of 10 healthy young men, researchers compared the effects of the intake of a single amino acid leucine or its equivalent bimolecular dileucine on muscle building and breakdown .
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Nat Commun: A small molecule amyloid inhibitor may be used as a new therapy to treat human cancer
Time of Update: 2021-08-07
Image source: https:// a research report entitled "Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function" was published in the international journal Nature Communications.
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function.
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Chinese scholar Neuron published a paper: The gating mechanism of human NMDA receptors and new small molecule binding sites
Time of Update: 2021-08-07
Cryo-electron microscopy analysis of the structure of the NMDA receptor bound to GNE-6901 revealed that the binding of small molecules in the GluN1 and GluN2A subunit ligand binding domain dimers caused a conformational change, making the receptor’s gated channel more open.
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The secret of human oral microbial small molecules promoting dental plaque formation revealed
Time of Update: 2021-03-18
The secret of human oral microbial small molecules promoting dental plaque formation revealed The secret of human oral microbial small molecules promoting dental plaque formation re
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Scientists have mapped the most accurate human RNA molecule m6A modification
Time of Update: 2021-03-14
reporter learned from the University of Liverpool, the university's Department of Biological Sciences, led by Dr. Meng Jia's research team, recently achieved a full transcription group RNA molecule m The most accurate prediction of A modification is equivalent to the most accurate m A surface transcription modification map ever made by humans.
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Cell: Identification of key host molecules hijacked by coronavirus to infect human cells
Time of Update: 2021-01-23
, from Cell, 2020, doi:10.1016/j.cell.2020.12.004 Co-author and director of the Glaston Virology Institute, said, "What's unique about our study is that we're not just looking at SARS-CoV-2, we're looking at other coronavirus at the same time." gives us a good understanding of drug targets that can widely suppress many coronavirus.
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Refresh your awareness! Scientists have found that the surface of human cells is stable attached to RNA molecules
Time of Update: 2020-11-13
past, it has been thought that RNA produced by the human nuclear genome does not exist on the surface of cells with complete cell membranes, and this new discovery has refreshed our understanding of cell surface molecules.
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Mol Cell: Special small RNA molecules play a key role in helicobacter pyridosis infecting humans
Time of Update: 2020-10-31
In this study, researchers found for the first time that the expression of small RNA molecules, such as NikS (not just proteins), is also affected by phase variation, which can be beneficial depending on the condition in the host's stomach, and that levels of small RNA molecules can be adapted to this condition by bit phase variation, which can lead to different regulation of pathogenic factors.
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Refresh your awareness! Scientists have found that the surface of human cells is stable attached to RNA molecules.
Time of Update: 2020-09-18
According to a research paper officially published in Gene Biology, Professor Zhongsheng of the University of California, San Diego (UCSD), and his team, led by co-authors Professors Zhang Liangfang and Chen Jin, identified these cell surface RNA molecules by genomic coding in the nuclea of cells using specially developed detection and sequencing techniques.
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How do human immune molecules perceive and destroy disease-caused bacteria?
Time of Update: 2020-09-06
Details of the molecular struggle between pathogenic bacteria and human immunity have been revealed by the University of East Anglia and the French Institute of Biological Structures, published in the journal Nature Communications.
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Study finds a molecule that regulates the development of multiple human cancers
Time of Update: 2020-06-01
The study, published recently in the journal Nature Communications, reveals how RPSAP52 RNA molecules trigger cell proliferation and eliminate their differentiation, making tumor cells more prone to r
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What are the benefits of small molecule peptide to human body?
Time of Update: 2019-08-12
Since the peptide industry was first-class in 2017-2018, we know more or less about peptide There are often some people who don't know how to take it, resulting in no effect Peptide is a peptide chain composed of protein and two to ten amino acids with a high-tech technology, that is, enzymatic hydrolysis technology, called peptide So let's take a look at the function and efficacy of compound small molecular peptide?
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The "high quality food" of human immune Corps was originally small molecule peptide
Time of Update: 2019-08-09
"Even if the thermoregulation system has lost, even if my efforts are meaningless, but as long as this body is still alive, I have no reason to give up my work." This is the determination of white blo