/>>The study was designed to evaluate the efficacy and safety of Zejimet® plus chemotherapy versus placebo plus chemotherapy in first-line treatment-naïve, stage IV NSCLC
J INTERN MED: The relationship between apolipoprotein A-IV concentration and clinical outcome in patients with chronic kidney disease
Time of Update: 2022-01-07
Researchers aimed to investigate the association between apoA-IV levels and all-cause mortality and cardiovascular outcomes in the German Chronic Kidney Disease (GCKD) study .
Lancet Haemat: Long-term prognosis of Bentuximab combined with chemotherapy in the treatment of stage III/IV classic Hodgkin’s lymphoma
Time of Update: 2021-09-29
In summary, after 5 years of follow-up, regardless of the status of PET-2, compared with the ABVD regimen, the A+AVD regimen showed a strong and lasting improvement in the progression-free survival rate of stage III or IV classic Hodgkin’s lymphoma.
in the treatment of stage IV non-small cell lung cancer in the form of an oral report at the 2021 World Lung Cancer Conference
Time of Update: 2021-09-18
CStone Pharmaceuticals announced that at the 2021 World Lung Cancer Conference (IASLC 2021 WCLC) organized by the International Association for the Study of Lung Cancer, the use
Overview of the development of mRNA vaccines: Part IV
Time of Update: 2021-09-13
Once in the host cell, the mRNA is translated into SARS-CoV-2 S protein, which is expressed on the surface of the host cell and induces neutralizing antibodies and cellular immune responses (Figure 3) .
J Immunother Cancer: Safety analysis of nivolumab in adjuvant treatment of stage III/IV melanoma
Time of Update: 2021-09-11
This article reports on the occurrence of nivolumab adjuvant-related adverse events (TRAE) in the Phase 3 CheckMate 238 trial, and assesses the possible association between safety and recurrence-free survival (RFS) .
Treatment plan for patients with stage IV lung squamous cell carcinoma
Time of Update: 2021-08-13
stage IV squamous non-small cell lung cancer: Phase 3 clinical study Lung-MAPS1400I
Time of Update: 2021-08-02
In advanced non-small cell lung cancer, the first-line treatment of nivolumab combined with ipilimumab improves the prognosis of patients compared with platinum-based chemotherapy .
Polyacrylic resin (IV)
Time of Update: 2021-07-29
Uses: This product is mainly used as a film coating material for Chinese and Western medicine tablets, pills, granules and other gastric-soluble drugs.
Ascent Pharmaceuticals APG-115 for the treatment of stage IIB-IV melanoma was approved as an orphan drug by the FDA
Time of Update: 2021-07-27
However, due to the particularity of the MDM2-p53 protein interaction, it has brought considerable difficulties to the development of small molecule inhibitors, leading to a handful of drugs under research in this field in the world .
CGRP-targeted migraine drug head-to-head study Eli Lilly launches Phase IV clinical trial of Emgality
Time of Update: 2021-06-22
On Tuesday, the company announced that in order to advance the science of migraine treatment and help understand the role of CGRP monoclonal antibodies (mAbs) and oral CGRP receptor antagonists in preventing migraines, it will conduct a head-to-head study.
Using machine learning algorithms to predict the recurrence of stage IV colorectal cancer after surgery
Time of Update: 2021-06-22
734, this model can still predict cancer recurrence; however, the gbm algorithm model has the highest AUC value (0.
of stage III or IV ovarian cancer: a placebo-controlled randomized phase III study (IMagyn050/GOG 3015/ENGOT- OV39)
Time of Update: 2021-06-16
research summary research summaryIn an intent-to-population (ITT) analysis, the median PFS of the atilizumab group and the placebo group were 19.
AstraZeneca's tremelimumab triple therapy has significant efficacy in the first-line treatment of stage IV NSCLC
Time of Update: 2021-06-10
On Friday, AstraZeneca stated that the addition of Imfinzi and tremelimumab to chemotherapy can significantly prolong the lives of patients newly diagnosed with stage IV or metastatic non-small cell lung cancer (NSCLC).
Bayer's pulmonary hypertension drug Adempas reaches its primary endpoint in Phase IV clinical trial
Time of Update: 2021-05-03
On March 29, Bayer announced the publication of Phase IV clinical data of the pulmonary hypertension drug Adempas (riociguat) in The Lancet Respiratory Medicine.
MR CLEAN-NO IV Study: Can anterior circulation stroke bypass intravenous thrombolysis and directly use endovascular treatment? 丨ISC2020
Time of Update: 2021-04-28
The MR CLEAN-NO IV trial aims to evaluate the effectiveness and safety of direct EVT and bridging therapy (IVT+EVT) in patients with AIS caused by anterior circulation occlusion.