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20 years of grinding a sword, "Science" magazine multiple papers reveal the key to HIV vaccine effectiveness
Time of Update: 2021-04-19
A paper published by this university on the 26th found that the CMV vaccine they designed produces an unusual T cell response, which effectively fights SIV in monkeys.
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Understanding NEJM in 2 minutes: the effectiveness of ALVAC-gp120 HIV vaccine
Time of Update: 2021-04-19
[Editor's note] NEJM Quick Take introduces an article of the latest NEJM in 2 minutes in the form of animation
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Pfizer/BioNTech's new crown vaccine has a 6-month effective rate of 91.3%
Time of Update: 2021-04-19
Pfizer/BioNTech stated that the co-developed COVID-19 vaccine is very effective in preventing symptomatic COVID-19 infection, with a protection period of up to six months after the second vaccination.
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Theory-Mechanism-Clinical, multi-target intervention of Jinlida granule has significant effect on diabetes
Time of Update: 2021-04-19
gave an in-depth explanation on the prevention and treatment of diabetes and the clinical application of Jinlida granules guided by collateral disease theory. The audience brought a wonderful academic feast. This article
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ADC drugs targeting CD22 are effective in children with R/R ALL
Time of Update: 2021-04-19
Recently, Professor Erica Brivio and others reported the results of a phase I clinical study (ITCC-059 trial) on the efficacy and safety of CD22-targeted ADC drug IO in the treatment of CD22+ children with R/R ALL.
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JAMA: The protective effect of vaccines against key mutations of the new coronavirus is much higher than that of natural infections
Time of Update: 2021-04-19
virus strain, was modified from the laboratory and contains mutations in the key receptor binding domain of the S protein of multiple emerging mutant strains. >The research team conducted a live virus
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JAMA: In response to the key mutations of the new coronavirus, the protective effect of the vaccine is much higher than that of natural infection!
Time of Update: 2021-04-19
circulating virus strain, was modified from the laboratory and contains mutations in the key receptor binding domain of the S protein of multiple emerging mutant strains. The mapping research team of WuXi AppTec's
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New use of old drugs, Pfizer’s drug may be effective against new coronary pneumonia
Time of Update: 2021-04-18
. 1038/s41467-020-17796-z In October of the same year, researchers from the University of North Carolina School of Medicine in the top journal "New England Journal of Medicine" (NEJM) Published a shocking image about the new coronavirus, which
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How effective is the host-oriented adjuvant treatment of tuberculosis?
Time of Update: 2021-04-18
Among the four targeted treatment drugs, the researchers found that CC-11050 and everolimus showed sufficient safety and tolerability in the treatment of tuberculosis patients.
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Glofitamab is expected to break through the curative effect bottleneck of R/R B-NHL
Time of Update: 2021-04-18
>Glofitamab is a new type of bispecific antibody with a novel 2:1 structure. It binds bivalently to CD20 of B cells and monovalently binds to CD3 of T cells to induce T cell activation and immune response against tumor cells, thereby achieving
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Umbralisib is expected to become a safe and effective treatment for R/R iNHL patients
Time of Update: 2021-04-18
Fowler and others conducted a phase IIb clinical study to evaluate the PI3Kδ/CK-1ε dual inhibitor Umbralisib in patients with relapsed or refractory indolent non-Hodgkin’s lymphoma (R/R iNHL) Efficacy and safety.
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The sooner the "German Rehabilitation Model" is activated, the better the effect of stroke rehabilitation will be!
Time of Update: 2021-04-18
International Medical Center show that stroke patients who received rehabilitation treatment within 6 months of onset have recovered well, and the Basel Index (assess the patient's ability to live independently ) The improvement rate reached 36
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Nature Sub-Journal: Breaking with traditional cognition, Xu Jian's team discovered the tumor suppressor effect of jumping genes
Time of Update: 2021-04-18
This study unexpectedly found that retrotransposon LINE-1 with complete transposition activity has a tumor suppressor function in the development of myeloid leukemia, and clarified that LINE-1 activates DNA damage checkpoints through retrotransposition and affects genome stability.
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Professor Tao Sun: Real-world studies confirm that Chidamide is safe and effective, and early treatment benefits are more significant | 2021 CSCO BC
Time of Update: 2021-04-18
Due to the above results, the combination of chidamide and exemestane in the treatment of advanced HR+ The phase III clinical trial ACE for breast cancer came into being.
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Tracking of infection cases of vaccinators-Experts: The vaccine is effective after being recovered soon without transmission to others
Time of Update: 2021-04-18
Only when there are sufficient data to show that the antibody level of the population after vaccination has been reduced to a very low level, and the disease or virus infection cannot be prevented, the booster injection will be considered.
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Kexing inactivated vaccine real-world protection effectiveness data released
Time of Update: 2021-04-18
website medRxiv, showing that Manaus, Brazil, where the P. 1 mutant virus strain is endemic, was inoculated with Beijing Kexing Zhongwei Bio ( The real-world data analysis of medical workers of the inactivated vaccine CoronaVac developed
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The real-world protection effectiveness data of Kexing inactivated vaccines are released from Brazil, where mutant virus strains are prevalent
Time of Update: 2021-04-18
Whether the existing new crown vaccine is still effective against these mutant strains is a question that researchers are eager to answer.
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, and the protective effect can be observed 14 days after the first dose of the vaccine
Time of Update: 2021-04-18
The results of this test showed that the protective effect of two doses of CoronaVac on symptomatic COVID-19 reached 50.
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COVID-19 vaccine, and the safety and effectiveness data show that it is consistent with overseas
Time of Update: 2021-04-18
The global data at the 2021 National Vaccine and Health Conference is very good, but what is the progress of the mRNA vaccine clinical trials carried out by Fosun Pharma in China?
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Dexamethasone combined with oseltamivir can effectively improve the efficacy of newly diagnosed ITP
Time of Update: 2021-04-18
Therefore, the team of Professor Ming Hou launched a multi-center, open-label, randomized phase II clinical trial comparing dexamethasone combined with oseltamivir and dexamethasone monotherapy in the treatment of adult newly diagnosed ITP.
