domino reaction: Construction of coumarin skeleton under the guidance of diversification
Time of Update: 2020-01-07
Lett.) finally, the author proposed the following reaction mechanism (Fig. 5): first, the phosphine catalyst is conjugated into alkyne ester, and then the intramolecular nucleophilic attack aldehyde group (MBH type reaction) produces ylide intermediate I.
Nat. Commun.: domino reaction of α - alkynic acid to β - aromatic aldehyde catalyzed by substrate recognition
Time of Update: 2019-10-31
It is an area of great concern for researchers to develop catalytic systems that can achieve efficient direct and selective chemical conversion
In this sense
Professor Yang Hua group of Central South University: Domino cyclization reaction based on 3-oxindole skeleton polarity matching
Time of Update: 2019-04-24
Because of its structure specificity and reaction diversity, methylene indole oxide has attracted more and more attention in the field of synthetic chemistry and pharmaceutical
and tetrahydroquinoline with alkynyl substituted quaternary carbon center by continuous domino 1,6-addition / cyclization catalyzed by organophosphine
Time of Update: 2019-02-27
The quaternary carbon centers with alkynyl groups in the lead are widely found in medicine and bioactive molecules, which have important synthetic value
At present, most
membered nitrogen heterocyclic compounds by multiple domino cyclization of thioylide
Time of Update: 2018-10-30
Lead six and seven nitrogen heterocyclic compounds exist widely in medicine and bioactive molecules, so it is very important to synthesize these compounds through cheap raw
Worldcoveries, University of Western Ontario, Canada and Yabao Pharmaceutical Group signed a contract in Beijing
Time of Update: 2014-03-11
Source: China Council for the promotion of drugs March 10, 2014, the cooperation and exchange meeting between research and innovation Department of Western Ontario, Canada and Beijing Municipal Commission of science and technology was held in Beijing.
of Ontario, Canada (a series of reports on the visit to the United States and Canada 9)
Time of Update: 2013-07-17
Source: China Council for the promotion of Medicine (CFDA) on July 16, 2013, a delegation led by song Ruilin, executive chairman of CFDA, was invited to hold a business negotiation
Delegation of China Pharmaceutical Association visited University of Western Ontario, Canada
Time of Update: 2013-07-16
In the afternoon, the delegation from the University of Western Ontario and the China Council for the promotion of drugs held a round table on medical and health policy and a promotion conference on the world coveries pharmaceutical innovation project.
President Song Ruilin meets with vice president of the University of Western Ontario and his delegation
Time of Update: 2013-04-26
China Pharmaceutical Council is very pleased to establish close ties with Canadian research institutions and innovative enterprises, including the University of Western Ontario, Canada, and carry out multi-level and multi field cooperation in technology exchange and policy research.
Domino effect shows the decline of soybean meal in the whole line
Time of Update: 2008-11-03
Introduction: on Wednesday, CBOT soybean contract fell to a halt in the near future, and the biggest support to maintain the hope of domestic soybean market bulls collapsed