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Polysorb nanoantibodies block SARS-CoV-2 infection and inhibit mutation escape

 Time of Update: 2021-03-08

The findings were published online January 12, 2021 in the journal Science under the title "Structure-guided multivalent nanobodies block SARS-CoV-2 infect and suppress mutational escape." antibodies are an important weapon for the immune system to fight infection.
Tiantian Bio announced that TJ107 has completed the first patient drug treatment in Phase 2 clinical studies in China

 Time of Update: 2021-03-08

On February 4, Tiantian Bio announced that its new long-acting recombinant human lebinocyte interlethional 7 (rhIL-7) TJ107 treatment of glioblastoma in China Phase 2 clinical trial has completed the first patient drug.
AkzoNobel's 2014 sales were 14.296 billion euros, down 2%

 Time of Update: 2021-03-07

Full-year 2014 sales fell 2%, offset by adverse exchange rate effects and divestitures, although sales rose 1% between all business areas.
Sanofi injects 2...

 Time of Update: 2021-03-07

NOVA, disease modeling and clinical trial simulation are increasingly being used in drug development to support decision-making.
What should we do about the SARS-CoV-2 virus mutants that have emerged in the UK?

 Time of Update: 2021-03-06

There are many mutations (nearly 20) from the UK, eight of which occur on the prick proteins used by the virus to adsorb and infect host cells, which are the targets of new vaccines and antibody development.
BioRxiv and Nature Sub-Journal Interpretation! A beneficial class of gut bacteria may play a key role in the treatment of type 2 diabetes!

 Time of Update: 2021-03-06

Communications entitled "Transkingdom interactions between Lactobacilli and hepatic mitochondria", scientists from institutions such as Oregon State University found that some microbes in the gut microbiome may play a key role in the onset of type 2 diabetes
Three companies have reached a strategic partnership on the type 2 diabetes drug Acapo sugar

 Time of Update: 2021-03-06

Wichida, a wholly owned subsidiary of Shanghai Hyundai Pharmaceutical Co., Ltd., will take advantage of the policy dividend of the Drug Listing License Holder (MAH) system, which allows holders to entrust entrusted manufacturers with the production of medicines.
New anti-inflammatory drugs! AbbVie IL-23 inhibitor Skyrizi's treatment of Crohn's disease (CD) 2 Phase III induction studies have been successful!

 Time of Update: 2021-03-06

, clinical remission was measured by CDAI (Crohn's Disease Activity Index) and PRO-2 (two-part patient reporting results). in the ADVANCE study, there was a significant increase in the proportion of patients treated with 600 mg or 1200 mg Skyrizi
COVID-19 shelter? The study found that SARS-CoV-2 attacks the brain and can cause serious illness

 Time of Update: 2021-03-05

Winter has come, the Spring Festival wants to come. With the increase in the flow of people, the new coronary pneumonia (COVID-19) outbreak caused by the new coronavirus (SARS-CoV-2) infection appears to have become more serious, with official
Calcium Measurements from Whole Heart Using Rhod-2

 Time of Update: 2021-03-05

Here, we describe the optical apparatus and the method to record intracellular calcium transients.
(DHE) INP104:15 minutes effective, 2 hours of remission!

 Time of Update: 2021-03-05

the drug was developed using Impel's proprietary Precision Olfactory Delivery (POD) technology and delivered directly to the blood vessel-rich upper nasal cavity, potentially providing convenience and clinical benefits for patients with acute migraines.
New anti-inflammatory drugs! AbbVie oral JAK1 inhibitor Rinvoq has been approved by the European Union to treat 2 new rheumatoids!

 Time of Update: 2021-03-04

studies, Rinvoq reached the primary endpoint of the ACR20 response compared to a placebo. , 15 mg doses of Rinvoq and Adamo monoantigen showed non-poor effectiveness in treating the ACR20 response at week 12. patients treated with Rinvoq
One year market value fell K drug sales in the last 2 years Mercadon 2021 can get back to a game?

 Time of Update: 2021-03-04

In 2021, vaccine giant Merca East opened its year with a cold splash of cold water on the development of a "crazy" new crown vaccine. January 25th, Mercedon will stop developing two candidate vaccines V590 and V591 for SARS-CoV-2/COVID-19.
Preparation of Escherichia coli Samples for 2-D Gel Analysis

 Time of Update: 2021-03-04

Escherichia coli has been studied for many years by two-dimensional polyacrylamide gel electrophoresis (2-D gels) ( 1 , 2 ). This method has provided much information about the physiology ofE. coli
Science: Virus sequences can reveal how SARS-CoV-2 spreads and evolves

 Time of Update: 2021-03-03

JANUARY 29, 2021 // -- The presence of SARS-CoV-2 variants in the fight against COVID-19 adds twists and turns, indicating the need for better genomic monitoring of the virus, said Katia Koell, associate professor of biology at Emory University.
JCEM: Relationship between stuttering and type 2 diabetes

 Time of Update: 2021-03-03

of the 4,443 adolescent men (0.4%) who stuttered, 162 (3.7%) had type 2 diabetes, compared with 25,678 (2.1%) of men who did not stutter (with an adjusted ratio of 1.3, 95% CI of 1.1-1.6).
Regenerative meta "stone man disease" new drug Phase 2 clinical success

 Time of Update: 2021-03-03

, regenerative meta announced the results of a trial of clinical LULINA-1 phase 2 in the treatment of aggressive musculoskeletalization (Fibrodysplasia Ossificans Progressiva, FOP) in the new drug garetosmab. Preliminary analysis after 28
Proteomics studies have helped identify potential drugs against SARS-CoV-2

 Time of Update: 2021-03-03

researchers at the University of California have been studying proteins used by SARS-CoV-2 virus to bind to lung proteins and have identified a variety of drugs that could be useful for treating COVID-19 patients.
: routine refrigeration, 2-pin immunity, global non-profit supply!

 Time of Update: 2021-03-03

The European Commission (EC) has granted COVID-19 Vaccine AstraZeneca Conditional Listing Permit (CMA) for active immunization of people 18 years of age and older to prevent new coronavirus pneumonia (COVID-19) caused by the new coronavirus (SARS-CoV-2).
Aachen Pharmaceutical Bcl-2 inhibitor APG-2575 was qualified as an orphan drug

 Time of Update: 2021-03-03

since 1983, the United States has adopted the Orphan Drugs Act to provide policy support to businesses to encourage the development of drugs for rare diseases.

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