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Science Sub-Journal: Human Orthogonal IL-2/IL-2Rβ System Enhances the Proliferation and Antitumor Effects of CAR-T Cells

 Time of Update: 2022-04-29

In this preclinical model, administration of ortho-hIL-2 to mouse recipients receiving CAR-T cell transplantation expressing ortho-hIL-2Rβ promoted CAR-T cell activation, proliferation, and antitumor efficacy with Limited systemic toxicity .
Hormone-free male contraceptives are 99% effective in preclinical trials and are expected to enter human trials by the end of the year

 Time of Update: 2022-04-25

On Wednesday, a team of scientists said they had developed a male oral contraceptive that was 99 percent effective in mice with no apparent side effects, and is expected to enter human trials by the end of this year .
Scientists develop coated probiotics that can effectively enter the human gut

 Time of Update: 2022-04-25

In the Nanyang Technological University study, probiotics, gut-friendly lactic acid bacteria, were sprayed with alginate (a carbohydrate derived from brown seaweed) to protect them from the harsh acidic environment of the stomach .
75% of the genes in the human body are garbage?

 Time of Update: 2022-02-25

Gu Chaojiang introduced that according to the early definition, the number of genes responsible for encoding proteins in human genes is only 40,000, accounting for only 2% of the genome, and the other 98% are classified as "junk DNA" .
JAHA: Effect of body mass index on postoperative atrial fibrillation in patients with hypertrophic cardiomyopathy undergoing septal myectomy

 Time of Update: 2022-02-18

Blood vesselThe aim of this study was to determine the effect of body mass index (BMI) on the development of postoperative atrial fibrillation in patients with obstructive hypertrophic cardiomyopathy undergoing septal myectomy .
The biological effects of chemical poisons in the body

 Time of Update: 2022-02-04

The toxic process of chemical poisons in the body includes absorption, distribution, excretion, accumulation and biotransformation .
Advances in intervention research on the effects of different diets, body weight and exercise

 Time of Update: 2022-01-24

　　On January 10, 2022, the Journal of Nutrition , a well-known international journal in the field of nutrition
Hong Kong University of Science and Technology Research: Human T cell immune response can effectively respond to Omi Keron

 Time of Update: 2022-01-09

The research team expects that the T cell immune barrier produced after vaccination and booster will continue to protect humans and reduce the chance of being infected by Omi Keron or other mutant viruses .
BMJ Sub-Journal: Maximum body mass index MBBO can effectively predict diabetes complications

 Time of Update: 2022-01-08

This study aims to clarify MBBO in predicting advanced diabetic micro vascular clinical value of complication development . 1136/bmjdrc-2021 -002466doi: 10.
PNAS: How do ultramicrobacteria in the environment adapt to life in the human body

 Time of Update: 2022-01-07

In order to verify this hypothesis, scientists developed a model system to experimentally study the function and influence of ADS on TM7x and its host bacteria .
Scientists have discovered a new gene that controls the left and right asymmetry of the human body

 Time of Update: 2021-12-28

>The results were published this week in the journal Nature Genetics . >At first glance, the human body seems to be symmetrical because our left side seems to be a mirror image
District of Nutrition, Shandong Academy of Agricultural Sciences, systematically evaluated the effect of whole grain food on the body's glucose metabolism

 Time of Update: 2021-12-26

clinical studies, covering 4118 patients, and systematically evaluated the effect of whole grain food intake on the body's blood glucose metabolism, and explored the relationship between dose-effect and time-effect
the agricultural products are located systematically evaluates the effect of whole grain foods on the body's glucose metabolism

 Time of Update: 2021-12-26

clinical studies, covering 4118 patients, and systematically evaluated the effect of whole grain food intake on the body's blood glucose metabolism, and explored the relationship between dose-effect and time-effect .
J. Future Food The beneficial effects of Pleurotus ostreatus on the body mass and food intake of healthy C57BL/6 mice

 Time of Update: 2021-12-24

Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice[J].
and Nutrition, Shandong Academy of Agricultural Sciences systematically evaluated the effect of whole grain foods on the body's glucose metabolism

 Time of Update: 2021-12-24

of Agricultural Products included 48 randomized controlled clinical studies, covering 4118 patients, and systematically evaluated the effect of whole grain food intake on the body's blood glucose metabolism, and explored the relationship between dose-effect
Technology and Business University: Anti-inflammatory and intestinal flora regulation effects of walnut peptide LPF in the body

 Time of Update: 2021-12-24

In summary, the walnut peptide LPF can relieve the symptoms of colitis and promote recovery by reducing cell apoptosis, anti-inflammatory effects and regulating intestinal flora .
The world's first pig kidney transplantation human body operation completed gene editing

 Time of Update: 2021-12-04

It is believed that after years of genetic modification of donor pigs, preclinical test results in non-human primates show that immune rejection has been basically overcome .
Diabetologia: Using human genetic data to study the effect of glucose-dependent insulin-promoting polypeptide signals on cardiometabolism

 Time of Update: 2021-12-03

>. Here, we use human genetic data to study the possibility of targeting GIP signals to treat cardiometabolic diseases . Therefore, the purpose of this study is to use
Human immunodeficiency virus and its effect on the pulmonary vascular bed

 Time of Update: 2021-12-03

In addition, the impact of other factors such as co-infection and illegal drugs can increase and change the impact on the pulmonary vascular bed, complicating the pathological and clinical effects of HIV .
Cardiovasc Diabetol: The effect of empagliflozin on ketone body levels in patients with stable chronic heart failure

 Time of Update: 2021-12-02

Diabetes blood vessels This study evaluated whether the SGLT 2 inhibitor Enpagliflozin increased the ketone levels in patients with stable CHF, and whether this increase would impair blood pressure and vascular function .

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