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CRISPR/Cas9 directed epigenetic editing reveals multiple transcriptional regulation and functional effects
Time of Update: 2021-10-21
Here, the author uses CRISPR/dCas9 technology to adapt to epigenetic editing through site-specific targeting of DNA methylation to describe the transcriptional changes of candidate genes and the functional impact on cell fate under different tumor environments .
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CRISPR contributes to the directional evolution of plants | Genome Biology
Time of Update: 2021-03-15
The Mahfouz team pioneered the design of 15,000 sgRNAs for the OsSF3B1 gene, using CRISPR-Cas9 technology to produce a corresponding amount of rice healing tissue bank.
We developed a CRISPR/Cas-based directed evolution platform in plants to evolve the rice (Oryza sativa) SF3B1 spliceosomal protein for resistance to splicing inhibitors.
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CRISPR/Cas9 system and twin virus vector system integrate in rice to achieve directed knock-in of foreign genes.
Time of Update: 2020-09-09
the study provides a simple and efficient method for omniogenic recombination or targeted tapping of exogenetation fragments in the plant genome, which will play an important role in gene functional research and crop fine breeding.
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Zhang Feng, discoverer of GENE editing technology CRISPR, explores the challenges, future applications and development directions of CRISPR!
Time of Update: 2020-08-09
June 9, according to foreign media reports, recently the Atlantic Monthly interviewed the gene editing technology CRISPR discoverer Zhang Feng, to discuss the technology's challenges, future applications and direction of development and other issues.
