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Li Long's group from the School of Life Sciences reveals the dynamic changes of the phospholipid transporter flippase in the cell membrane

 Time of Update: 2022-04-19

This paper reports the conformational changes of phospholipid transferase (lipid flippase) in different lipid membranes, and discovers the resting state of this protein family for the first time, which provides an important molecular basis for understanding the formation of cell membrane asymmetry .
BLOOD: Targeted membrane-bound anionic phospholipid anticoagulation therapy can improve the outcome of traumatic brain injury in mice

 Time of Update: 2021-10-19

Their research article was published in the journal BLOOD, Severe Traumatic Brain Injury TBI Severe Traumatic Brain Injury TBI Here, they showed the results of a study designed to test anticoagulation against EVs expressing anionic phospholipids The agent prevents TBI-IC and improves the outcome hypothesis in mice suffering from severe TBI .
Statistical Thermodynamics Through Computer Simulation to Characterize Phospholipid Interactions in Membranes

 Time of Update: 2020-12-19

This chapter describes the major issues thDepartment of Physiat are involved in the statistical thermodynamics of phospholipid membranes at the atomic level. The ingredients going into models of lipid bilayers are summarized: force fields, representation of long-range interactions, and boundary conditions.
Sensitive and Specific Fluorescent Probing of Oxidative Stress in Different Classes of Membrane

 Time of Update: 2020-12-06

Reactive-oxygen species and organic free radicals are essential metabolic intermediates and have important regulatory functions. Quantitative assays of lipid peroxidation in intact cells are essential for evaluating oxidative damage from various sources, and in testing the efficacy of antioxidant interventions.

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