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Green Chemistry: the research group of Wu Dalei Irwin reported the electrochemical [4 + 2
Time of Update: 2020-02-26
Sulforamide is a kind of important heterocyclic compounds It is not only an important precursor in synthetic chemistry, but also a common skeleton in many drugs, agricultural chemicals and bioactive c
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Guo Haiming, Professor of Henan Normal University: synthesis of polycyclic fused anisodane by asymmetric dearylation cycloaddition of 2-nitrobenzofuran
Time of Update: 2020-01-17
The introduction of anisodane skeleton (8-azabicyclo [3.2.1] octane) is widely found in many natural products and drug molecules These compounds play a key role in the clinical treatment of immune, ne
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JACS: Construction of cyclobutene by enantioselective [2 + 2] cycloaddition of alkyne and alkene Derivatives Catalyzed by cobalt
Time of Update: 2019-09-27
The functionalized cyclobutane and cyclobutene are a kind of important molecular skeleton, which widely exist in many natural products with biological activity and drug molecular structure (Figure 1a)
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JACS: nickel catalyzed [5 + 2] cycloaddition of benzothiophene and alkyne to synthesize 12 π electronic nonaromatic heptahydrobenzothiophene
Time of Update: 2019-08-27
It is of great significance to study the C-S bond cleavage and catalytic conversion of sulfur-containing aromatic compounds catalyzed by transition metals for understanding the mechanism of devulcaniz
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synthesized by [2 + 1 + 1 + 1] cycloaddition reaction of thiogerate and tert butyl nitrite
Time of Update: 2019-07-08
Lead heterocyclic compounds are generally contained in many drugs, materials and bioactive molecules Furazan derivatives are important NO donors and have very important biological activities, such as
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Angelw: Ru (II) catalyzes the series reaction of C-H Allylation and [3 + 2] dipolar cycloaddition of allylic acetals
Time of Update: 2019-05-21
Azomethionine imines have been widely used in cycloaddition reactions with various coupling agents such as alkenes, alkynes and allylites In addition, in the C-H functionalization reaction, researcher
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Angelw: CO catalyzed intermolecular [2 + 2] cycloaddition of alkynes and alkenes
Time of Update: 2019-02-01
Cyclobutane and cyclobutene derivatives are important structural segments in natural products and bioactive compounds, and are also commonly used synthesis intermediates Among them, [2 + 2] cycloaddit
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substituted 1,2,4-triazole by [3 + 2] cycloaddition of cyanylide and diazonium salt catalyzed by copper
Time of Update: 2018-09-18
Lead organic nitriles can react with diazo compounds to obtain nitrile ylides easily and quickly, and [3 + 2] cycloaddition with alkenes can construct a variety of five membered nitrogen heterocyclic
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Angelw: Construction of decalin derivatives by enantioselective (4 + 2) cycloaddition
Time of Update: 2018-09-02
Decalin ring is widely found in diterpenoids, steroids and other natural products (Figure 1) These compounds usually have anti-inflammatory, antibacterial and anti-tumor activities Therefore, the synt
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ring compounds by using the strategy of [3 + 2] cycloaddition / [3,3] rearrangement in series
Time of Update: 2018-08-13
The author: Professor Mo Dongliang's research group has been one of the most challenging front topics in organic synthesis due to the adverse effects of ring tension and entropy increase Aza-9-membere
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Chem. Comm.: regioselective [2 + 2] cycloaddition of cinnamates and related olefins
Time of Update: 2017-10-10
Cyclobutane skeletons are common in natural products, and they are found in plants, insects and microorganisms Most of these structures have biological activity, which makes them have potential in dru