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CheckMate 142 study nivolumumab + low-dose ipilimumab first-line treatment of MSI-H/dMMR

 Time of Update: 2021-10-21

medication options . References: [1] Lenz HJ, Cutsem EV, Limon ML, et al. First-Line Nivolumab Plus Low-Dose Ipilimumab for Microsatellite Instability-High/Mismatch Repair
Clin Gastroenterology H: In elderly patients with inflammatory bowel disease, the risk of serious

 Time of Update: 2021-10-20

This study confirmed that elderly patients with IBD who received vedolizumab had a lower risk of infection-related hospitalization compared with patients who started anti-tumor necrosis factor therapy .
Chinese scientists achieve high production of L-homoserine in E. coli

 Time of Update: 2021-10-20

Link to the paper: https:// id="gtx-trans" > 　　L-homoserine is a naturally occurring non-protein amino acid, which can be used as a pharmaceutical intermediate and has a good market prospect .
Clinical Gastroenterology H: Drinking coffee can reduce liver stiffness but can't organize liver steatosis

 Time of Update: 2021-10-20

diabetes Based on the results of the CAP measurement of American adults, this study confirmed that drinking coffee is associated with lower liver stiffness, but not with steatosis .
J Clin Oncol: The efficacy of nivolumab combined with low-dose ipilimumab in the first-line treatment of MSI-H/dMMR metastatic colorectal cancer

 Time of Update: 2021-10-20

metastatic MSI-H/dMMR CRC received nivolumab (1 time/2 weeks) combined with low-dose ipilimumab (1 time/6 weeks) until the disease progressed . The primary endpoint is the objective response rate
E-magy raises 5 million euros in a new round of financing to further develop silicon anode materials

 Time of Update: 2021-10-16

? For E-magy, the entry of new capital will help increase the output of the nanoporous silicon pilot production line and accelerate its qualification program with automakers and battery manufacturers .
The trend of diversification of chemical raw materials is obvious. E-commerce platform injects vitality into the industry

 Time of Update: 2021-10-11

Global Coatings Network News: Global Coatings Network News: In the future, the importance of unconventional raw materials will become increasingly prominent, market players will become more diversified, and the rise of e-commerce platforms will bring new vitality.
"Cold" thinking under the "hot" of fresh food e-commerce

 Time of Update: 2021-10-10

After several rounds of fierce battles, fresh food e-commerce, which is believed to have a trillion-dollar market, is still bustling, but it is still chaotic and unclear
Johns Hopkins University found thousands of unknown chemicals in e-cigarettes

 Time of Update: 2021-10-09

The problem is that e-cigarette aerosols contain other unidentified chemical substances, which may affect We don’t know about health hazards,” said Carsten Prasse, an assistant professor of environmental health and engineering at Johns Hopkins University and senior author .
Huazhong helps companies to realize petrochemical e-commerce standard stores online

 Time of Update: 2021-10-03

, and effectively promotes self-selling by production enterprises in the region from the perspective of serving the production enterprises in the area and helping to tap potential and increase efficiency. Products were launched on the petrochemical e
Professor Deng Yanhong: Facing the challenge, real cases of MSI-H/dMMR colorectal cancer show new strategies for immunotherapy!

 Time of Update: 2021-10-01

study showed that the ORR of Envolimab as a single agent (150 mg QW administration) for the second-line treatment of 103 patients with MSI-H/dMMR was 42. 7%, including 65 patients with CRC, and the ORR reached 43. 1%
Clin Gastroenterology H: STAT6 variants are associated with recurrence of eosinophilic esophagitis

 Time of Update: 2021-09-29

This study confirmed that children with EoE patients who initially responded to PPI treatment and carried STAT6 variants rs324011, rs167769, or rs12368672 had an increased risk of recurrence after 1 year of PPI maintenance .
Clin Gastroenterology H: Severe liver damage during hospitalization of COVID-19 patients has nothing to do with liver insufficiency or death

 Time of Update: 2021-09-29

> The new crown virus (SARS-CoV-2) expression on vascular angiotensin converting enzyme cell has a receptor tropism
Professor Jiang Yun-Interaction between E. coli O157:H7 and Pseudomonas meat-derived mixed biofilm formation

 Time of Update: 2021-09-28

coli O157:H7 and Pseudomonas meat-derived mixed biofilm formation SummaryThe interaction between different bacteria affects the formation of mixed bacterial membranes.
Clin Gastroenterology H: Physical weakness of hospitalized patients with inflammatory bowel disease is independently associated with mortality and readmission rate

 Time of Update: 2021-09-28

Among them, 15,507 patients were considered frail, and the independent effects of frailty on disease burden and hospitalization costs, in-hospital mortality, readmission and surgical risks, and reasons for readmission were evaluated .
Chuanwei Chemical's self-sold products are all online in petrochemical e-commerce

 Time of Update: 2021-09-20

every month, and incorporate it into the monthly sales report for public release . >　　In order to improve the intelligence and automation of the standard seller and buyer center
Clin Gastroenterology H: The effect of HBeAg on the risk of hepatocellular carcinoma during oral antiviral treatment in patients with chronic hepatitis B

 Time of Update: 2021-09-19

/>00–1. 67) . >>>Figure: HBeAg on the risk of hepatocellular carcinoma during oral antiviral treatment of patients with chronic hepatitis B
Clin Gastroenterology H: Normalization of fecal calprotectin levels within 12 months of diagnosis

 Time of Update: 2021-09-19

>At present, 1 out of every 352 people in the world suffers from Crohn's disease (CD). CD is a type of transmural intestinal inflammation that relapses and relieves
E-health can improve the quality of life of informal caregivers of stroke patients

 Time of Update: 2021-09-19

Recently, an article published in the Journal of Nursing Scholarship, an authoritative nursing journal, clarified the evidence related to the application of electronic health to improve the quality of life of non-regular nursing staff of stroke patients .
Clin Gastroenterology H: What are the risk factors for colorectal stenosis in ulcerative colitis?

 Time of Update: 2021-09-19

. The median follow-up time was 9. 6 years . The incidence of colorectal stenosis was 3. 6%

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