cells published on November 7 in the academic journal Nature Communications. is expected to obtain functional cells, including pancreatic cells, hematopoietic stem cells, and so on, from human pluripotent stem cells in alien chimerics.
Diabetogia: Akap1 defects mediated by NDUFS1 caused by mitochondrial dysfunction and apoptosis in mice exacerbated diabetic cardiomyopathy.
Time of Update: 2020-07-27
our study is the first to show that a lack of Akap1 hinders mitochondrial translocation of NDUFS1, leading to mitochondrial dysfunction and apoptosis of myocardial cells, which can exacerbate diabetic cardiomyopathy.
Nature peruse the details. Breakthrough, said good apoptosis, the nervous system partial lying on a cell focal death.
Time of Update: 2020-07-21
Subsequently, the authors, through the conduct experiments of Il1r-//Il18r,Gsdmd-//--3knockout mice, determined that Gsdmd-//mouse phenotype was similar to Aim2-//-rat, indicating that the anxiety behavior caused by the absence of aim2 inflammatory small body was cell focal length mediated by gasminder-D.
Cell apoptosis and checkpoint suppression! Asain Pharma has partnered with Mercado to develop MDM2
Time of Update: 2020-07-15
Recently, the company announced a clinical partnership with Merck and Co to evaluate its MDM2-p53 inhibitor APG-115 and Mercado's anti-PD-1 therapy Keytruda (Corrida, generic name: pemzumabrob, Pabolizumab) to treat patients with advanced solid tumors.
Cell Rep: In Alzheimer's disease, apoptosis protein caspase is associated with abeta-induced synaptic loss
Time of Update: 2020-07-14
researchers speculated that one of the mechanisms by which A-beta induces synaptic damage was associated with amyloid beta precursor protein (APP) being cut by caspase at the D664 thio, releasing C31 peptides that may be cytotoxic.
Asia-Sheng Pharmaceuticals Announces Latest Clinical Data on New Drugs for Apoptosis Series
Time of Update: 2020-06-17
APG-115 APG-115 is an oral bio-available, highly selective small molecule MDM2 inhibitor developed by AXA Pharmaceuticals. APG-115 has a high affinity for MDM2, which restores p53 tumor inhibition by blocking MDM2-p53 interactions. APG-115
Blood: JAK/STAT signal suppression enhances the sensitivity of CD8 T cells to dexamethasone-induced apoptosis
Time of Update: 2020-06-16
Recently, researchers found that cytokine-induced JAK/STAT signals mediated resistance of T-cell acute lymphoblastic leukemia (T-ALL) cells to dexamethasone, which RUX can effectively reverse.
Deciphering the "black box" of white blood cells apoptosis, scientists find potential new target for myeloid leukemia
Time of Update: 2020-06-07
Not long ago, Professor Fu Caiyun of Zhejiang University of Technology found for the first time that neurotrophic peptide receptor 1 (NK-1R) showed significantly high expression in peripheral blood of myeloid leukemia patients, and revealed
Apoptosis induced by silybin (sb)
Time of Update: 2020-04-03
In addition, silibinin (sb) can induce apoptosis of colon cancer HT-29 cells, but no activation of Caspase-3, caspase-9 and PARP and release of cytochrome C were observed.
The first phase of "recombinant human tumor necrosis factor related apoptosis inducing ligand for injection" was completed
Time of Update: 2020-04-03
On March 24, humanwell said at the 2013 performance presentation meeting that the first class new drug "recombinant human tumor necrosis factor related apoptosis inducing ligand
-report photosensitizers for in situ monitoring apoptosis process
Time of Update: 2019-04-11
Although photodynamic therapy (PDT) has been widely used as a promising cancer treatment method in the scientific community, high activity photosensitizers and strong light still
Weigh! Nfs1 protects lung cancer cells from iron apoptosis
Time of Update: 2017-11-30
In a new study, researchers from New York University School of medicine and other research institutions found that blocking a protein can release oxygen to destroy iron dependent
How protein interaction drives apoptosis
Time of Update: 2017-07-26
In this new study, the researchers used fluorescence correlation spectroscopy to quantify a small Bcl-2 interaction network, including three major components, CBID, Bax and Bcl XL, and studied these protein networks in a roughly cell simulated environment.
Research Progress on proanthocyanidins and apoptosis of grape seed extract
Time of Update: 2016-08-04
This article reviews the biological activity, animal and clinical experimental research, mechanism of action and application prospect of proanthocyanidins in order to promote the development and application of these drugs.
Study on the effect and mechanism of Trifolium extract on the apoptosis of human lung cancer H1299 cells
Time of Update: 2015-01-21
Recently, researchers from the Department of oncology, Tongde Hospital Affiliated to Zhejiang University of traditional Chinese Medicine published a paper to explore the effect
The regulatory effect of AMPK on apoptosis of bronchial epithelial cells induced by cigarette smoke extract
Time of Update: 2014-12-26
The results showed that CSE could induce apoptosis of NHBE cells in a time-dependent and concentration dependent manner, and the expression of AMPK might have a protective effect on cell resistance to CSE induced ER stress.
Apoptosis of Hep2 cells induced by Cistanche deserticola polysaccharide extract
Time of Update: 2014-10-29
The components of polysaccharide extract were analyzed by high-throughput chromatography, cell cycle and apoptosis protein were analyzed by flow cytometry, and apoptosis related protein was detected by Western blot.
Myocardial extracts of rats inhibit the apoptosis of bone marrow mesenchymal stem cells induced by hypoxia and serum-free
Time of Update: 2014-07-14
Recently, researchers from cardiothoracic surgery, the First Affiliated Hospital of Wenzhou Medical University published a paper to observe the inhibition of myocardial tissue
Protective effect of turmeric extract on apoptosis of sk-n-sh cells induced by Na 2S 2O 4
Time of Update: 2014-04-28
The effects of turmeric extract on SOD and MDA were detected by spectrophotometry, cell survival rate by MTT colorimetry, apoptosis rate by TUNEL, and caspase-3 protein expression by Western blot.