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    ubiquitylate

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    • Assessing Ubiquitylation of Rho GTPases in Mammalian Cells
      Time of Update: 2020-12-05
      Rho GTPases including RhoA, Cdc42, and Rac1 are master regulators of cell cytoskeleton dynamic, thus controlling essential cellular processes notably cell polarity, migration and cytokinesis. Recent findings have unveiled another layer of complexity in the regulation of Rho proteins consisting in their ubiquitylation followed by their proteasomal degradation.
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