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The cornerstone of nano-drug delivery-the role of EPR effect in human tumors
Time of Update: 2022-06-26
In view of this, researchers such as Wenguang Liu of Tianjin University have developed an in vitro perfusion model to study the role of EPR in human kidney tumors in real time through X-ray computed tomography (CT) .
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Insights into human immunity from Omicron "Nature" long article
Time of Update: 2022-06-20
Preliminary data show that the current vaccine designed against the original strain of the new coronavirus is not effective in preventing Omicron infection, but appears to reduce hospitalization or mortality .
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Science|Li Jing et al. discovered and identified CD8+ T cell subsets with regulatory functions in the human body
Time of Update: 2022-06-19
In conclusion, the authors discovered and identified a new subset of CD8+ T cells with regulatory functions in humans, which can selectively suppress pathogenic T cells that trigger autoimmune responses, thereby contributing to the maintenance of peripheral immune tolerance.
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Cell Stem Cell Human-derived pluripotent stem cells remodel the midbrain dopamine pathway
Time of Update: 2022-06-05
. A number of clinical works have pointed out that this therapy can significantly alleviate the motor dysfunction in patients with long-term Parkinson's disease [3
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Cancer Cell recognizes human lung cancer antigens
Time of Update: 2022-06-02
In conclusion, the authors identified a set of CD39 and CXCL13-based molecular signatures of T cells that can rapidly recognize tumor antigens by analyzing the transcriptome and TCR of tumor-infiltrating lymphocytes from four patients with non-small cell lung cancer .
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Ying Tianlei/Wu Yanling/Ding Lin of Fudan University jointly develop a new generation of fully human nanobody conjugated drugs for solid tumors
Time of Update: 2022-06-01
>. Further, the researchers mutated the serine at position 85 in the fully human nanobody n501 to cysteine to realize the site-specific conjugation of the small molecule drug SN38, and named this new
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pathological protein fibril aggregates formed by TMEM106B in the human brain
Time of Update: 2022-05-31
In this study, researchers discovered a previously unknown cluster of novel pathological proteins extracted directly from the brain tissue of a Parkinson's disease dementia (PDD) patient with dementia and two elderly healthy controls.
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A mutated new coronavirus has been detected in 154 wild white-tailed deer, fearing to infect humans again?
Time of Update: 2022-05-30
In addition, the polluted environment, the infiltration of human wastewater into animal water sources, and the spread of other intermediate hosts may all bring the new coronavirus to white-tailed deer .
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protein fibril aggregates formed by TMEM106B in human brain
Time of Update: 2022-05-29
development opportunities and favorable treatment. Interested applicants please contact: hspdworkshop@163. com . Talent recruitment[1] "Logical Neuroscience
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"Posting is human nature" mechanism found!
Time of Update: 2022-05-28
Until recently, a study published in Science revealed the important role of the PROK2-PROKR2 neural pathway in the transmission of pleasurable touch.
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Tecoro TDM-105795 Initiates Phase Ib Human Clinical Trial of Androgenetic Alopecia
Time of Update: 2022-05-28
On February 28, 2022, Tecoro Bio announced that its topical TDM-105795 tincture for patients with androgenetic alopecia (AGA) completed the first clinical phase 1b (MAD) trial in the United
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New research shows that humans have amazing 'nutritive intelligence'
Time of Update: 2022-05-26
by American pediatrician, Dr. Clara Davis, put a group of 15 infants on a diet that allowed them to be "free," in other words, what they wanted to eat, from 33 different food items . While
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Dietary fats, human nutrition and the environment: balance and sustainability
Time of Update: 2022-05-26
> . >The research, published in the journal Frontiers in Nutrition, provides a framework for predicting the likely impact of changes in oil production and trade on poor and malnourished
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HUMAN BRAIN MAPPING: Deformation of the right anterior hippocampus is associated with genetic risk for substance use disorders
Time of Update: 2022-05-24
>Substance use disorder (SUD) is prevalent in SUD
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Although the disinfectant is strong, don't be too vigilant about its impact on the environment and human body
Time of Update: 2022-05-24
All localities responded positively and paid more and more attention to the adverse effects of disinfection by-products in the process of epidemic prevention and control .
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JNNP: methionine homozygosity for PRNP polymorphisms and susceptibility to human prion disease
Time of Update: 2022-05-24
Here, we performed the current case-control study using this large database to assess the association of the codon 129 PRNP polymorphism, a major determinant of CJD, with the development of prion disease .
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Biositu and BeiGene Reach a Collaboration on the Licensed Use of RenMab/RenLite Fully Human Antibody in Mice
Time of Update: 2022-05-23
BeiGene”) licenses the use of the RenMab®/RenLite® fully human antibody mouse platform with independent intellectual property rights of Biositu to develop various types of antibody drugs such as fully human monoclonal antibodies and double antibodies .
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Increase human healthy lifespan by 10 years?
Time of Update: 2022-05-22
Cell reprogramming studies are expected to move toward clinical proof-of-concept within the next four years .
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2022-04-19 PNAS Zhou Congzhao and Chen Yuxing's research group discovered a novel regulatory mechanism of the human phospholipid flipperase ATP8B1
Time of Update: 2022-05-20
/> Three-dimensional structures of ligand-free and substrate-bound ATP8B1-CDC50A complexes>
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Cell Reports: Genome-wide identification and analysis of prognostic biomarkers in human cancer
Time of Update: 2022-05-20
Recently, researchers at Yale University School of Medicine published an article titled "Genome-wide identification and analysis of prognostic features in human cancers" in the journal Cell Reports, which established a rich resource for prognostic biomarker analysis.