>Dementia is one of the leading causes of disability and dependence in older adults, as it affects memory, thinking, behavior and the ability to perform daily activities
HUMAN BRAIN MAPPING: Deformation of the right anterior hippocampus is associated with genetic risk for substance use disorders
Time of Update: 2022-05-24
>Substance use disorder (SUD) is prevalent in SUD
npj Parkinsons Dis: Genetic research finds that Parkinson's and lipid metabolism are closely related
Time of Update: 2022-05-24
> . immunityLipids are primarily known for their role in energy storage, but they are also major components of cell membranes, part
Nat Genet: Delaying DNA replication fork speeds leads to cell fate changes and enhances cell reprogramming efficiency
Time of Update: 2022-05-23
The relevant research results were published online in the journal Nature Genetics on March 7, 2022, with the title of "DNA replication fork speed underlies cell fate changes and promotes reprogramming" .
Largest-ever schizophrenia study published reveals genetic links to disease
Time of Update: 2022-05-21
Relevant research results were published online in the journal Nature Genetics on April 8, 2022, with the title "Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia" .
Healthy lifestyle helps prevent gestational diabetes in people at highest genetic risk
Time of Update: 2022-05-20
In the Finnish Gestational Diabetes Prevention Study (RADIEL), study subjects received intensive physical activity and dietary counselling during pregnancy and in the first year postpartum .
japonicum at the chromosome level and analyzed the genetic basis of the host adaptation of Schistosoma japonicum
Time of Update: 2022-05-20
>. The study used three-generation sequencing, Hi-C , full-length transcriptome ( Iso-Seq ) and other
Genetic alterations explain chemotherapy resistance in germ cell cancer
Time of Update: 2022-05-19
Professor Dr Leendert Looijenga, who led the study, said: "In the future, our findings may help identify high-risk germ cell cancer patients so that doctors can offer alternative treatments if chemotherapy doesn't work .
A&R: Host genetics, not commensal microbiota, determines initial development of systemic autoimmune disease in BXD2 mice
Time of Update: 2022-05-19
RESULTS: In 6 -month-old mice, GF status did not affect splenomegaly, GC B cells, age-related B cells, or serum autoantibody levels, with the exception of IgG anti-histone .
A 12-year follow-up study of 410,000 people: Genetic factors + unhealthy lifestyle can increase the risk of gout by up to 200%!
Time of Update: 2022-05-19
Kaplan-Meier survival curves showed that the risk of developing gout was highest for people with high genetic susceptibility and an unfavorable life> .
Blood: Scientists identify novel genetic target to treat adult blood cancer
Time of Update: 2022-05-18
org/blood/article-abstract/139/10/1541/482776/Genome-wide-CRISPR-screen-identifies-CDK6-as-a?redirectedFrom=fulltext"Our findings suggest that CDK6 may be a very attractive target for the treatment of ATLL, and that in some ATLL cell lines, loss of TP53 function may render cells resistant to the CDK6 inhibitor Palbociclib," said researcher Nakagawa.
Nature Genetics: Why don't most smokers get lung cancer?
Time of Update: 2022-05-18
>On April 11, 2022, researchers from the Albert Einstein College of Medicine in the United States published a research paper entitled: Single-cell analysis of somatic mutations in human bronchial epithelial
"Measure" what you need, flexible and "ordered" The new SeqStudio Flex genetic analyzer is launched
Time of Update: 2022-05-18
”Renew CE, make everything possibleThe SeqStudio Flex Series Genetic Analyzers are based on proven Applied Biosystems technology, with improved optimized designs and technologies to make them efficient, flexible, easy to use, and intelligently connected .
New study analyzes complete genetic blueprint of more than 18,000 cancer samples, uncovers new mutational patterns
Time of Update: 2022-05-16
Scientists have analyzed the complete genetic blueprint of more than 18,000 cancer samples, uncovering new mutational patterns that could help doctors deliver better, more personalized treatments .
Next stop in genetic sequencing: mapping the genetic diversity of all races
Time of Update: 2022-05-15
) An international consortium of scientists published a paper in the journal "Nature" published on the 20th, saying that more than a dozen research institutions are cooperating on the "Human Pan-Genome Project", which aims to Create a reference genome
Newly discovered severe genetic defect in humans increases risk of dying from vaccines and simple viral infections
Time of Update: 2022-05-14
A new genetic defect found in Inuit ancestry in Greenland, Canada and Alaska could lead to screening all newborn Inuit who would otherwise be at risk of dying from childhood vaccines or simple viral infections .