Novo Nordisk's application for high-dose semaglutide for the treatment of diabetes is rejected by the FDA
Time of Update: 2021-03-26
Although more information needs to be included in the resubmission, Novo Nordisk stated that the company believes that the completed clinical trial projects are sufficient to support semaglutide's label extension application.
10-year follow-up results of the first phase 3 study: rituximab combined with high-dose
Time of Update: 2021-03-22
Oncology Group’s performance status score (ECOG PS) of 0-3 are eligible for inclusion. Using the Pocock minimization algorithm, patients were
JAMA: Randomized double-blind trials confirmed that single high-dose vitamin D3 therapy was not effective in patients with moderate to severe COVID-19
Time of Update: 2021-02-25
Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial.
Green leaf pharmaceutical high-dose Liss' permeable skin patch has been approved for sale in Germany
Time of Update: 2021-02-24
's single-day permeable patch for the treatment of Alzheimer's disease is one of the core products of Leafy Pharmaceuticals in the central nervous field.
BMJ: High doses of cycloprogesterone acetate lead to a significant increase in the risk of meningoma
Time of Update: 2021-02-10
139,222 participants received at least 3g of cycloprogesterone acetate over a six-month month, identified as acetate cycloprogesterone exposure, and 114,555 participants received a cumulative dose of less than 3g, which was considered to be mildly exposed (control group).
Denmark Launches High-Dose Nordic Berry Extract
Time of Update: 2021-02-07
/> Asiros preparing to put the Nordic red (black tea) extract on the market. Morten Weidner believes that the berries are rich in polyphenols and have obvious health properties, but have not yet been widely used in the food
JAMA Netw Open: Supplementing high doses of vitamin D during pregnancy does not improve neurodevelopment in future generations
Time of Update: 2021-02-01
, when neurodevelopmental assessments were conducted, the addition of high doses of vitamin D had no effect on the overall cognitive score of 3-year-olds compared to the standard dose.
JAMA Network Open: Effects of trialic adsive vs trialic high-dose inactivated influenza vaccine
Time of Update: 2021-01-25
was higher, and in the same clinical trial, there was no direct comparison of the safety of aIIV3 and HD-IIV3, nor was there a comparison of the relative effects of aIIV3 and HD-IIV3 reactions on the health-related quality of life (HRQOL) in older adults
Clin Trans Gastroenterology: High-dose proton pump inhibitors are superior to standard-dose proton
Time of Update: 2021-01-23
GBS s 8 is the best critical point for determining high-risk re-bleeding patients (GBS≥8), with significant differences in recurrence rates between SD-IVP (17/61, 27.9%) and HD-IVP (7/65,10.8%).
Sugar-lowering drugs to treat Alzheimer's disease (AD)! Novo Nord launches a high-dose oral semaglutide (Smeglutide) Phase 3 clinical project!
Time of Update: 2020-12-26
CVOT, a trial conducted in patients with type 2 diabetes at high risk of CV, showing that Rybelsus reached the primary endpoint of compound MACE endpoint non-poor performance when combined with placebo, demonstrating CV safety. study
JAMA: Effects of high-dose influenza vaccine on mortality and hospitalization risk
Time of Update: 2020-12-13
recently looked at the effects of increasing vaccination doses on reducing influenza-related hospitalizations associated with high-risk cardiovascular disease.
Clin Cancer Res: Multiple myeloma . . The "high dose" of amine is not loved
Time of Update: 2020-11-26
This is a multi-center, randomized, open-label clinical trial in which patients with multiple myeloma after ASCT and high doses of lenamin (25 mg/day) consolidation therapy (CT) were randomly assigned to the LenMT 25 mg/day group or 5 mg/day group.
Research and Development Daily treats type 2 diabetes Lilly Trulicity has added two new high-dose labels
Time of Update: 2020-11-16
reached the main therapeutic end, but missed the safe end. Abivax oral anti-inflammatory drug treatment of ulcerative colitis phase IIa trial success recently, Abivax company published ABX464 treatment ulcerative colitis (UC) phase IIa study of 2
Lancet Neurol: Effects of high-dose biotin on disability progression in patients with advanced multiple sclerosis
Time of Update: 2020-11-06
(defined as minimum disability), and have an extended disability scale (EDSS) score of 3.5-6.5, The 25-foot walk (TW25) lasted less than 40 seconds, there was evidence of clinical disability progression, and there was no recurrence within 2 years of joining
Novart's high dose of Enerzair Breezhaler significantly reduced the rate of acute asthma attacks in moderate to severe.
Time of Update: 2020-10-14
showed that patient safety in high-dose triple therapy was consistent with previous findings in the III/IIIb PLATINUM clinical development program. analysis supports the potential of high doses of IND/GLY/MF as an effective stage treatment
Oncologist: Nivolumab plus low-dose Ipilimumab offers new treatment options for patients
Time of Update: 2020-10-12
In patients receiving immuno-checkpoint inhibitors, early detection and treatment of treatment-related adverse events (TRAEs) can improve treatment outcomes. in CheckMate 142, nivolumab (3 mg/kg) plus low dose ipilimumab (1 mg/kg) is previously
Br J Nutr: Short-term consumption of high doses of sucralose does not change blood sugar control, insulin resistance, or gut microbiome in healthy people.
Time of Update: 2020-10-12
, eating high doses of sucralose 7 d does not change blood sugar control, insulin resistance, or gut microbiome in healthy individuals.
A real hammer! High doses of vitamin C have been shown in the journal Science to enhance cancer immunotherapy!
Time of Update: 2020-10-03
Photo Source: Science Translational Medicine As early as the 1970s, medical researchers suspected that giving cancer patients high doses of vitamin C might help reduce tumor growth, but subsequent studies failed to find any benefits and researchers lost interest.
Innovative triple therapy for asthma! Novart Enerzair Breezhaler: High doses significantly reduce asthma exacerbation compared to medium doses!
Time of Update: 2020-09-27
, acetic aciddatero/Glon bromide/mormisone; IND/GLY/MF) Key III IRIDIUM Study (NCT02571777). results showed that in patients treated with moderate or high doses of LABA but with uncontrolled asthma, Enerzair Breezhaler significantly reduced
Based on the high-flow xenon-source scientific device HINEG, the ultra-sensitive dose range of high-energy neutrons to nematodes was found.
Time of Update: 2020-08-07
of Technical Biology and Agricultural Engineering of Hefei Research Institute, conducted an experiment on the effectofs of high-energy neutron radiation damage, which found the ultra-sensitive dose range of high-energy neutrons against nematodes