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Nature sub-journal: How to manage skin involvement in patients with systemic sclerosis?
Time of Update: 2022-06-20
In addition, these studies also found that the skin gene expression profile of patients with SSc changes over time and parallels the clinical progression of skin involvement [7-9] .
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Insights into human immunity from Omicron "Nature" long article
Time of Update: 2022-06-20
Preliminary data show that the current vaccine designed against the original strain of the new coronavirus is not effective in preventing Omicron infection, but appears to reduce hospitalization or mortality .
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Nature review: NK cells fight cancer, these development directions deserve attention
Time of Update: 2022-06-19
Strategies to Enhance NK Cell Function Cytokines that Stimulate NK Cells Antagonists of various activating or inhibitory cytokines are currently being evaluated in clinical trials .
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Is Nature Lost Weight Loss Motivation?
Time of Update: 2022-06-19
In another model of AD induced with ovalbumin and papain, obese mice also showed more severe allergic airway responses, such as increased cellular infiltration across multiple immune subpopulations .
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Nature Immunol type I cytokines cooperate to promote the body's inflammatory response
Time of Update: 2022-06-18
These data suggest that during the progression of chronic neuroinflammation, the MTPT process occurs in the central nervous system, and classical monocytes with high Ly6C expression accumulate at the site of inflammation through terminally differentiated inflammatory macrophages .
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Nature Metabolism Yang Weiwei/Zhao Yun/Yao Feng Reveal a New Mechanism of Pyruvate Dehydrogenase in Lung Cancer Immune Escape
Time of Update: 2022-06-17
In conclusion, in this study, we explored the role of PDH in tumor immune evasion and demonstrated that activated oncogenic signaling induces subcellular translocation of PDHE1α, thereby enhancing tumor cell resistance to immunotherapy, thereby promoting Development of lung cancer .
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NATURE IMMUNOLOGY Blockbuster: Subverting the traditional understanding of immunogenic cell death
Time of Update: 2022-06-16
The article suggests the importance of immunogenic cell death in the etiology of non-infectious, non-malignant diseases related to self-reaction .
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[Nature Sub-Journal] Opening the "black box" of immune checkpoint LAG3 - developing blocking therapies to treat cancer and autoimmune diseases
Time of Update: 2022-06-14
Recent studies have pinpointed how LAG3 regulates T cell activity, providing important insights into the development of other LAG3-blocking therapies to treat cancer and autoimmune diseases .
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The natural gas market develops steadily in the "14th Five-Year Plan" of my country's natural gas industry
Time of Update: 2022-06-14
Important discoveries continued to be made in Sichuan and Tarim basins; natural gas production reached 94 billion cubic meters, a year-on-year increase of 10.
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Jiang Yi/Xu Huaqiang from Shanghai Institute of Materia Medica, Nature Sub-Journal Reveal
Time of Update: 2022-06-13
iNatureNeuromedin U receptors (NMUR), including NMUR1 and NMUR2, are a group of Gq/11-coupled G protein-coupled receptors (GPCRs) . NMUR1
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The natural gas market develops steadily
Time of Update: 2022-06-13
Important discoveries continued to be made in Sichuan and Tarim basins; natural gas production reached 94 billion cubic meters, an increase of 10.
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Nature sub-issue: Sun Yat-sen University Yu Huichuan team found that infection with new crown will accelerate aging
Time of Update: 2022-06-12
, obesity, and more . Therefore, understanding the biological aging of severe versus non-severe cases of COVID-19 may be very useful for modeling and predicting the progression
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"Nature" heavy: Li Ming's team discovered a new type of anti-cancer T cells!
Time of Update: 2022-06-11
, revealing that an immune A new mechanism of anti-cancer, and the discovery of a T cell with great anti-cancer potential is expected to promote the development of immunotherapy in a new direction .
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Nature sub-issue: Yang Yuanjian's team from Jiangxi Mental Health Center found that the longevity factor Klotho may have antidepressant potential
Time of Update: 2022-06-10
After specifically increasing the expression of Klotho protein in the NAc brain region by the viral vector tool, it can significantly improve the social impairment, anhedonia and other depression-like behaviors caused by chronic stress .
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"China Natural Gas Development Report (2020)": The growth rate of natural gas consumption this year is expected to slow down significantly
Time of Update: 2022-06-08
58 trillion cubic meters, an increase of approximately 600 billion cubic meters year-on-year; the national natural gas (including extraordinary (Regulated gas) production reached 177.
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Nature: Why is the mRNA vaccine developed for the original strain effective against Omicron when used as a booster?
Time of Update: 2022-06-08
After a SARS-CoV-2 mRNA Boost in Nature . The study showed that a third dose of the mRNA vaccine developed for the original new coronavirus (SARS-CoV-2) strain enhanced
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Nature: LAG-3, the next outlet?
Time of Update: 2022-06-01
At the LAG3 Targeted Drug Development Summit held in January this year, Paul Moore from MacroGenics said that the PD-1×LAG-3 bispecific antibody Tebotelimab can simultaneously block the growth of a single T cell.
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Nature: Major progress!
Time of Update: 2022-05-30
Studies have demonstrated the existence of neuroimmune-vascular junctions in the adventitial segments of atherosclerotic disease in mice and humans, as shown by the formation of growth cones near the axon terminals of immune cells and smooth muscle cells .
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Nature Aging Feng Jianfeng/Cheng Wei of Fudan University reveals that 7 hours of sleep every night
Time of Update: 2022-05-29
and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health" in Nature Aging. Data from the UK Biobank (nearly 500,000 people, mostly participants aged 38-73 of European ancestry, including
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Nature's universal CAR-T announces preclinical data targeting two hematological malignancies
Time of Update: 2022-05-29
in previous preclinical studies of CD123-targeted CARs Disadvantage . "References: 1. https:// 2. https://cellectis. com/en/products/ucarts/3. https
