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k cell immunology

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Sinopec's first independently-owned fuel cell-grade hydrogen test facility started successfully

 Time of Update: 2022-06-25

Recently, Sinopec’s first test facility with independent property rights that can produce fuel cell-grade high-purity hydrogen was successfully started at Gaoqiao Petrochemical, marking an important step in Sinopec’s new energy strategic transformation.
Science｜Li Jing et al. discovered and identified CD8+ T cell subsets with regulatory functions in the human body

 Time of Update: 2022-06-19

In conclusion, the authors discovered and identified a new subset of CD8+ T cells with regulatory functions in humans, which can selectively suppress pathogenic T cells that trigger autoimmune responses, thereby contributing to the maintenance of peripheral immune tolerance.
Cell sub-issue: Zhu Yongqun's team and others reveal the mechanism of monoclonal antibody 35B5 neutralizing Omicron

 Time of Update: 2022-06-19

The research paper by disrupting the N-glycan switch via a conserved Spike epitope reports that the full-spectrum human monoclonal antibody 35B5 of SARS-CoV-2 VOCs can potently neutralize Omicron and reveal its novel mechanism of action .
Science 'trained' memory cells in mouse gut

 Time of Update: 2022-06-19

Collectively, this work identified a population of trained immune memory cells, Tr-ILC3s, in the mouse gut, which proliferated and rapidly produced IL-22 when re-encountered by pathogens after initial pathogen infection, thereby promoting mucosal defense .
Nature review: NK cells fight cancer, these development directions deserve attention

 Time of Update: 2022-06-19

Strategies to Enhance NK Cell Function Cytokines that Stimulate NK Cells Antagonists of various activating or inhibitory cytokines are currently being evaluated in clinical trials .
What are the characteristics of the high content live cell intelligent imaging and cloud analysis system

 Time of Update: 2022-06-18

3. High-Content, Versatile CytoSMART™ Omni's large optical window allows you to easily acquire full-area scan images of cell culture plates, flasks, petri dishes or other transparent culture vessels .
A review of the research progress of leukemia stem cells in acute T lymphoblastic leukemia

 Time of Update: 2022-06-18

with humanized NOTCH1 mAb decreased NOTCH1(mutated) T- The LSC survival rate and self-renewal ability of ALL LSC-transplanted mice, and lead to the depletion of CD34(+)CD2(+)CD7(+) cells with continuous engraftment ability, provide a new direction
Five departments "reward for subsidies" boost the fuel cell vehicle industry

 Time of Update: 2022-06-18

Reward funds are coordinated by local governments and enterprises for the industrialization of key core technologies of fuel cell vehicles, talent introduction and team building, as well as the demonstration and application of new models and new technologies, etc.
Related to Chimeric Antigen Receptor T-cell Therapy (2022 Edition)

 Time of Update: 2022-06-17

> The incidence of ICANS related to the treatment of CD19 and BCMA CAR-T cell products currently on the market is 28%-87% . In two real-world studies
Zhong Ling/Yang Zhenglin Reveals Tumor Heterogeneity Between Different R-ISS Stages in Multiple Myeloma Patients Using Single-Cell Transcriptomics

 Time of Update: 2022-06-16

/>Recently, Yang Zhenglin's research group from Sichuan Provincial People's Hospital published a research paper entitled "Exploring the R-ISS stage-specific regular networks in the progression of Multiple Myeloma at single-cell resolution
Potential Treatment for TP53 Altered Aggressive B-Cell Lymphoma

 Time of Update: 2022-06-16

> In ZUMA-1, axicabtagene ciloleucel (Axi-cel), a first-in-class CD19-targeted CAR (CAR19) T cell product, achieved in r/r aggressive B-NHL following ≥2 lines of systemic therapy An objective response rate (ORR) of 82
NATURE IMMUNOLOGY Blockbuster: Subverting the traditional understanding of immunogenic cell death

 Time of Update: 2022-06-16

The article suggests the importance of immunogenic cell death in the etiology of non-infectious, non-malignant diseases related to self-reaction .
Marginal zone B cells 'eaten' dendritic cells to 'hijack' their antigen-presenting function

 Time of Update: 2022-06-15

/>To test the above hypothesis, we detected the binding of MHC II to C3dg by co-immunoprecipitation experiments, but the MHC IIa–C3dg complex could not be detected if MHC II was deglycosylated with PNGase F
Chunfu Zheng publishes vaccine design targeting pathogenic fungal FTR1 in Frontiers in Immunology

 Time of Update: 2022-06-15

effective, the vaccine structure is also safe . Finally, we use in silico cloning to simulate vaccine large-scale production .
Cell therapy cutting-edge completes $120 million in financing, focusing on eye diseases

 Time of Update: 2022-06-14

> Headquartered in Seattle, Boston and Tokyo, Aurion Biotech aims to restore sight to millions of patients through life-changing regenerative therapies . The company's first drug candidate
Prof. Qingyuan Zhang: Advances in the treatment of relapsed and refractory diffuse large B-cell lymphoma 2021 China Oncology Congress

 Time of Update: 2022-06-13

The results of a phase Ib/II study of Pola combined with Glofitamab in the treatment of R/R DLBCL showed that the combination therapy achieved ORR of 79.
Cell Death Dis︱Kong Hui et al reveal the role of P2X7/NLRP3 inflammasome pathway in early diabetic retinopathy

 Time of Update: 2022-06-13

/> Kong Hui from the Ophthalmology Department of Qilu Hospital of Shandong University, Dr. Kong Hui and others published a paper entitled "Targeted P2X7/NLRP3 signaling pathway against inflammation, apoptosis, and pyroptosis of retinal
[Cell Sub-Journal] Researchers successfully map the single-cell transcriptome of diffuse large B

 Time of Update: 2022-06-13

mechanisms and therapeutic strategies . " The researchers performed droplet-based single-cell RNA-sequencing of more than 94,400 cells in 17 DLBCL patients, analyzing single-cell
Universal CD20 CAR-γδ T cell therapy has been granted Fast Track designation by the US FDA. What are the advantages of γδ T cells?

 Time of Update: 2022-06-12

April 21, 2022/eMedClub News/--On April 19, 2022, Adicet Bio announced that the U. S. FDA has granted its CD20-targeting allogeneic CAR-γδ T product candidate ADI-001 Fast Track designation
Prof. Ji Linong: Where does the saying that "East Asians have poor β-cell function" come from?

 Time of Update: 2022-06-11

-cell function (HOMA-β) and insulin resistance (or insulin sensitivity) (HOMA-IR or HOMA-S, HOMA-IR and HOMA-S have an inverse relationship) and further study the relationship between the two in the above-mentioned ethnic groups. the law

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naive cells immunology immunology dendritic cells in cancer immunology and immunotherapy agglutination immunology immunological assays immunology chart elisa immunology nlr immunology

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