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Nature Cancer of Sun Yat-Sen University found that mitochondrial fission promotes macrophage phagocytosis of cancer cells by regulating phase transition
Time of Update: 2022-08-11
The components WIP and WASP phase transition, thereby promoting the phagocytosis of cancer cells by macrophages , and found that mitochondrial fission changes two important aspects of the phagocytosis machinery .
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Nat Commun︱Guo Ming's team discovered a new mechanism of mitochondrial fission and a new target for the prevention and treatment of Parkinson's disease
Time of Update: 2022-04-28
In the follow-up research to further explore the functions of PINK1 and parkin, Professor Guo Ming's team found that PINK1 and parkin regulate mitochondrial morphology[2], and combined with the Drosophila model and human cell model, they successively found that the genes MUL1, VCP/p97, Atg1 can effectively inhibit the The mitochondrial damage caused by the deletion of PINK1 and parkin provides multiple potential drug targets for the prevention and treatment of PD[3-5] .
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Nature: Mitochondrial fission requires protein DRP1, but not dynein
Time of Update: 2022-03-02
Mitochondrial fission, which is required for the maintenance of the mitochondrial network, relies on a GTPase called dynamin-related protein 1 (DRP1, also known as DNM1L) .
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Intelligence will help the development of traditional Chinese medicine pharmaceutical equipment industry to accelerate the realization of fission
Time of Update: 2021-08-11
[ Hot attention from Chemical Machinery and Equipment Network ] Previously, the "Opinions on Promoting the Inheritance and Innovation and Development of Traditional Chinese Medicine" issued by the st
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Nature. Notch3 is a key receptor for the differentiation and pathological development of rheumatoid arthritis fission membrane fibroblasts.
Time of Update: 2020-07-21
these results suggest that the positional identity of synovial fibroblasts is regulated by Notch signal from endothelial cells, and this signal interaction between stroma is the source of inflammation and pathological basis of inflammatory arthritis.
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Link between vascular inflammation and mitochondrial fission abnormalities
Time of Update: 2020-05-12
May 11, 2020 /PRNewswire/--- most cells in the human body contain tiny "power plants" called mitochondria that generate a lot of energy for daily activities Like dynamic renewables, these small powe
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Advanced equipment of traditional Chinese medicine promotes the fission of traditional Chinese
Time of Update: 2019-02-28
[industry trends of China Pharmaceutical network] data shows that China's traditional Chinese medicine industry is currently about 900 billion yuan, accounting for about one-third of the total output
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Integration of Chuanxiong into innovative development mode to realize "fission" of supply side reform
Time of Update: 2017-08-04
[China Pharmaceutical network industry trends] in order to make the Chuanxiong industry bigger and stronger, Yinfeng town actively guided local Chuanxiong cooperatives to sign cooperation agreements w
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Pharmaceutical R & D, policy led "chain fission"
Time of Update: 2016-03-16
Source: medical geography 2016-03-16 this spring's "flat thunder", or the comprehensive promotion of Sanming mode, or the sudden end of electronic supervision code From the perspective of the author,
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In Vivo Labeling and Analysis of Mitochondrial Translation Products in Budding and in Fission Yeasts
Time of Update: 2020-12-12
The budding yeastSaccharomyces cerevisiae and the fission yeastSchizosaccharomyces pombe are excellent models to identify and study factors required for mitochondrial translation.
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Heterologous Expression of GPCRs in Fission Yeast
Time of Update: 2020-11-23
The high degree of conservation between GPCRs from different organisms has facilitated the development of a large number of model systems to enable study of this pharmaceutically important family of cell-surface receptors.
