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JACS: ingenious construction of natural product salimabromide
Time of Update: 2018-07-19
Salimabromide (scheme 1a, 1) is a kind of polyketone compound with antibacterial activity isolated from myxobacteria
Its dense functional group structure and rigid four
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Professor Dong guangbin's research group completed the synthesis of natural products enmein, isodocarpin and sculponin R
Time of Update: 2018-05-30
Int. ed.) the total synthesis of enmein and isodocarpin (scheme 3): the author developed a unique method of reducing alkenylation to construct D / E ring.
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Good news! The domestic diabetes market will change, and the application for production of heavy
Time of Update: 2018-05-28
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new undertaking of drug review and approval: this week (may 19-may 25, 2018), the new undertaking of domestic drugs is as follows: A kind of On May 24, the application
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Synthesis and structural modification of c31-c67 fragment in marine natural product amphidinol 3
Time of Update: 2018-04-19
Int. ed.) after obtaining 1a and 1b, the author compares their NMR data with natural products, and the difference of chemical shifts of c31-c51 parts of AM3 and 1A or 1b is shown in Figure 3.
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J. Am. Chem. SOC.: asymmetric total synthesis of natural products hippolachnin A and gracioethers
Time of Update: 2018-01-28
SOC.) the research work was completed by Tang Yefeng research group, School of pharmacy, Tsinghua University and Dieter Enders, Professor of Aachen University of technology, Germany.
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289 what products will be eliminated naturally?
Time of Update: 2017-12-18
Recently, the office of quality and efficacy consistency evaluation of generic drugs launched the column of quality and efficacy consistency evaluation of generic drugs on CDE
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It's not a hoax! It can't synthesize all the natural products. It can also send angelw
Time of Update: 2017-12-17
The author envisages that aza3 can be obtained by the oxidation of ketone 4 through desilication ether protecting group and C1, and 4 can be converted from allyl alcohol 5.
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Aging: new intelligent learning system shows strong natural product screening ability
Time of Update: 2017-12-15
The census bureau predicts that by 2030, one in five people in the United States alone will be over 65 years old
Many of today's most prevalent, costly and devastating
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Angelw: collective total synthesis of natural product xanthanolide
Time of Update: 2017-11-29
Professor Yefeng Tang's research group, from the school of pharmacy, Tsinghua University, has long been committed to the full synthesis of complex natural products, including many compounds of xanthanolide family.
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Chem. SCI.: new and old spectral techniques work together to decipher complex natural products
Time of Update: 2017-11-27
SCI.) Martin and Gustafson, this study represents the first application of RDC and rcsas to provide a new way to study the structure of natural products.
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Appreciate the art of organic synthesis: the synthesis of natural products by Hughes and gleasond, virosaine a
Time of Update: 2017-10-18
Securinega alkaloids are a series of natural products of indoleazide
The typical characteristics of the alkaloids are the bridged four ring structure containing α, β
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J. Nat. Prod.: new development of "smart" tools to help uncover natural products
Time of Update: 2017-10-11
The author first takes "the face of a molecule" as an example to explain how to understand the "first impression" of a newly discovered compound through analytical instruments in the field of natural product research.
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Angelw: a new synthetic route of natural product actinophyllic acid
Time of Update: 2017-10-10
Professor David Y
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Chen of Seoul National University in Korea and Professor Hidetoshi Tokuyama of Northeastern University in Japan jointly published
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Organic Letters: Total synthesis of complex phloroglucinol natural products from the Myrtaceae family
Time of Update: 2017-10-07
In order to modify the structure of myrtucomulone J and obtain sufficient amount for subsequent drug evaluation and new drug development and research, the research team was inspired by the synthesis of students, and established an efficient bionic synthesis strategy.
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J. Nat. Prod.: extraction and identification of natural product ω - n-methyl-4-hydroxytryptamine (norpsilocin) from Pleurotus ostreatus
Time of Update: 2017-09-22
If not freeze-dried before extraction, then water may cause reaction in the extraction process, make some natural products into derivatives, change the chemical structure, and affect the actual distribution ratio.
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Late functionalization of natural products by super electrophilic silane ions
Time of Update: 2017-09-21
Functional sources of complex natural products catalyzed by fluoroarylborane: the author of nature chemistry selected three fluoroarylborane Lewis acids (Fig. 2a) and silanes with different intensities to activate and modify different natural products (1, 3 and 5).
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Organic Letters: Total synthesis of complex phloroglucinol natural products from the Myrtaceae family
Time of Update: 2017-09-19
In order to modify the structure of myrtucomulone J and obtain sufficient amount for subsequent drug evaluation and new drug development and research, the research group successfully established an efficient bionic synthesis strategy inspired by the synthesis of students.
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Journal of natural products: caffeinol may help reduce the risk of type 2 diabetes
Time of Update: 2017-09-16
Type-2 diabetes (T2D) is a major chronic disease threatening human health worldwide
There are 30.3 million people suffering from diabetes in the United States, and type
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Angelw: asymmetric biomimetic synthesis of hispidain a, a natural product of Rabdosia
Time of Update: 2017-08-04
Isodon of Labiatae in the world is a group of plants with rich resources and modern distribution centers in western Yunnan, Western Sichuan and Southeast Tibet
The plant
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Asymmetric total synthesis of 19 dehydroxyl arisandilactone, a natural product of Schisandra chinensis
Time of Update: 2017-07-25
Nearly 60% of small molecule chemical drugs come from natural products and their analogues
As an important source of innovative drugs, natural products with complex
