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The latest research: Is the "magic drug" metformin really effective in the treatment of breast cancer?
Time of Update: 2022-08-10
Effects of metformin versus placebo on invasive disease-free survival and overall survival While the study found metformin to be ineffective in treating the most common type of breast cancer, the trial found a potentially important result for the treatment of a less common but more aggressive type of breast cancer, HER2-positive breast cancer .
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JAMA sub-issue: Whether metformin can "assist" lung cancer treatment, the key may be this indicator!
Time of Update: 2022-02-20
The trial included patients with EGFR mutation-positive non-small cell lung cancer (NSCLC) and randomly assigned to receive EGFR-TKIs alone or the combination of EGFR-TKIs and metformin (500 mg twice daily) .
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Transl Oncol: Metformin-salicylic acid treatment can improve prostate cancer treatment
Time of Update: 2021-09-29
Diabetic metforminRecently, researchers from Canada published an article in "Transl Oncol", investigating whether MET+SAL treatment can enhance PrCa tumor suppression and improve the response to RT .
Combined metformin-salicylate treatment provides improved anti-tumor activity and enhanced radiotherapy response in prostate cancer; drug synergy at clinically relevant doses .
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Brit J Cancer: Analysis of the efficacy of metformin in the treatment of resophageal colorectal cancer in the same group
Time of Update: 2021-01-17
in the multivariate model, both RAS mutation status and disease control at 12 weeks affected the participants' total survival rate (HR was 2.28, 95% CI was 1.12-4.7, p=0.02; HR was 0.21, 95% CI was 0.08-0.5, p=0.001).