CRISPR/Cas gene editing system adds new members, Shanghai University of Science and Technology team breaks smallest record
Time of Update: 2021-09-20
. This week, following the publication of the small Cas13 gene editing system by the team of well-known scholar Professor Zhang Feng, three more small CRISPR/Cas research "groups" from China, South
Potential genes that affect the severity of brain development
Time of Update: 2021-09-20
"The researchers conducted further studies and found that in the white LRP2 mutant and the wild type of the strain, certain genes, including ULK4 and PTTG1, were significantly up-regulated compared with black 6 mice .
Nature Sub-Journal: Genes that control the severity of colon cancer
Time of Update: 2021-09-20
Picture: Majid Kazemian and a group of scientists discovered that the TCF-1 gene plays a key role in controlling TReg cells and affects the severity of colon cancer .
Nature Sub-Journal: Which gene can control colon cancer?
Time of Update: 2021-09-20
" Original search:TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
Scientists have discovered genes that control the color patterns of cats
Time of Update: 2021-09-20
Through this analysis, the research team determined the expression of a gene called Dickkopf 4 (Dkk4) on the epidermis, marking the area on the fetal skin where hair follicles grow, which later produce pigment .
Chinese Academy of Sciences Scholars Science Sub-Journal discovers key genes for iron content in plant seeds
Time of Update: 2021-09-20
September 4, 2021, Science sub-Journal Science Advances issued Innovation Center for Molecular Plant Sciences, Chinese Academy of Excellence Chao-generation Indian research group entitled "NPF transporters in synaptic-like vesicles control delivery of iron and copper to seeds" of research papers .
Chao Daiyin's research team discovered key genes for iron content in plant seeds, which is expected to solve the "hidden hunger" problem
Time of Update: 2021-09-19
September 4, 2021, Science sub-Journal Science Advances issued Innovation Center for Molecular Plant Sciences, Chinese Academy of Excellence Chao-generation Indian research group entitled "NPF transporters in synaptic-like vesicles control delivery of iron and copper to seeds" of research papers .
Science: "Noisy" gene expression plays a key role in development!
Time of Update: 2021-09-19
While studying HIV, Weinberger's team discovered the existence of some molecules that can increase noise or switch the expression mechanism between active and inactive states, but strangely, they do not affect the average expression level .
Smoking during pregnancy may affect fetal growth by changing placental gene expression
Time of Update: 2021-09-19
The findings published in the journal Nature Communications also indicate that these DNA methylation changes in the placenta may affect the expression of genes related to environmental response, growth, and inflammation, which may explain the effects on fetal growth.
The first Morquio A syndrome rat model, gene therapy shows therapeutic potential
Time of Update: 2021-09-19
corrected the severe systemic changes in the rat model after a single intravenous injection of the viral vector . This research opens the door to future treatments that can be administered
Research progress and prospect of adeno-associated virus in gene therapy
Time of Update: 2021-09-19
>. >AAV is considered to have better safety due to its lower immunogenicity and site-specific integration ability . However, neutralizing antibodies against AAV
CRISPR-like gene cutting enzymes found in microorganisms
Time of Update: 2021-09-19
, Cas9 cooperates with RNA fragments to guide enzymes to find and cut specific DNA sequences . This technology relies on RNA as a guidance system, which is a key reason for its versatility and wide
An important breakthrough: the self-correction function of genes can resist blood cancer
Time of Update: 2021-09-19
Recently, a new study conducted by scientists at Johns Hopkins University found that the genes in the "chromosome cap" can fight gene mutations through self-correcting functions, thereby helping to fight blood cancer .
CRISPR gene editing therapy aimed at functional cure of HIV infection is about to start phase 1 clinical trial
Time of Update: 2021-09-18
Reference materials:[1] Excision Receives FDA Clearance of IND for Phase 1/2 Trial of EBT-101 CRISPR-Based Therapeutic for Treatment of HIV.
Retrieved September 15, 2021, from https:// /09/15/2297456/0/en/Excision-Receives-FDA-Clearance-of-IND-for-Phase-1-2-Trial-of-EBT-101-CRISPR-Based-Therapeutic-for-Treatment-of -HIV.
New technology makes studying gene function easier, faster and more effective
Time of Update: 2021-09-18
Simple selection and laborious screeningThe idea behind this new technology is to use another gene to mark the gene of interest, rather than a physical feature to make the flies resistant or sensitive to specific drugs .
Using CRISPR gene editing to improve cell therapy Vertex reaches a $1.2 billion collaboration
Time of Update: 2021-09-13
On August 24, Vertex Pharmaceuticals and Arbor Biotechnologies announced that the two parties will launch a new collaboration to use Arbor's proprietary CRISPR gene editing technology
are optimistic. When will the spring of gene therapy products come?
Time of Update: 2021-09-13
On the same day, Vertex Pharmaceuticals and Arbor Biotechnologies announced that they will launch a new collaboration to use Arbor’s proprietary CRISPR gene editing technology to enhance the development of innovative cell therapies for the treatment of serious diseases .
Research progress has been made on the role of genes and environmental factors in the processing of large and small illusions
Time of Update: 2021-09-13
In the early visual cortex, genes can explain about 39% of the variation in neural activity related to the overestimated component of the size illusion (the target circle is surrounded by a group of small circles) .
Professor Yin Yuxin: A new mechanism for the anti-cancer gene PTEN family member PTENɑ to promote tumor immune escape
Time of Update: 2021-09-13
The research paper, for the first time, described the molecular mechanism of PTENɑ, a member of the PTEN family, that promotes tumor immune escape by reducing the sensitivity of tumor cells to host immune attacks .
