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JNNP: The significance of gene screening for amyotrophic lateral sclerosis system
Time of Update: 2021-02-26
common genetic cause of amyotrophic lateral sclerosis is the amplification of the GGGGCC (G4C2) hexanucleotide repeat sequence in the first inclusion of the C9orf72 gene. in the UK queue study, this rate of expansion in fALS and sALS cases was 43
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A new gene for the development of rice spikes was cloned
Time of Update: 2021-02-26
) Recently, Wan Jianmin, a researcher at the Crop Science Research Institute of the Chinese Academy of Agricultural Sciences and a member of the Chinese Academy of Engineering, cloned OsPEX5, a new gene for the development of rice spikes
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Scientists have discovered the genes that cause antibiotic resistance
Time of Update: 2021-02-26
A previously unknown gene that causes antibiotic resistance has been discovered in an assessment of levels of multidring-resistant bacteria in London, Scientific Reports has published.
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Science: Changes in a single gene distinguish modern humans from Neanderthals?
Time of Update: 2021-02-26
To answer this question, Muotri's team used CRISPR gene editing techniques to edit stem cells from modern humans, introducing mutations in the Neanderthal NOVA1 gene that simulate "Neanderthalized" brain organs.
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Short Double-Stranded Ribonucleic Acid as Inhibitor of Gene Expression by the Interference Mechanism
Time of Update: 2021-02-26
The siRNA approach is close to antisense oligonucleotide technology and takes advantage of the progress of chemically synthesized oligoribonucleotides.
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CRISPR gene editing successfully treats cancer in living animals
Time of Update: 2021-02-25
/> CRISPR-Cas9 gene editing has the potential to permanently destroy tumor survival genes, overcoming repeated dose limits in traditional cancer therapies and improving treatment effectiveness. However, Cas9 and sgRNA are large, have some
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Blood: Results of clinical trials of BAX 335 gene therapy for type B haemophilia
Time of Update: 2021-02-25
human F9 genes into liver cells. report the results of a new study, "BAX 335 hemophilia gene therapy clinical trial results: potential impact of CpG sequences on gene expression", published recently in the journal Blood. BAX 335 Expression
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Bluebird Bio's gene therapy is priced second only to Zolgensma
Time of Update: 2021-02-25
, a well-known biotech company, Bluebird Bio, recently announced the price of its gene therapy, Zynteglo, for about $1.8 million, making it the second drug on the market to sell for more than $1 million, said.
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Generation of gene deletions and gene replacements in Escherichia coli O157:H7 using a temperature sensitive allelic exchange system
Time of Update: 2021-02-25
In this work we describe protocols for the generation of gene deletions and gene replacements using a temperature sensitive plasmid in Escherichia coli O157:H7.
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Perhaps 5% of autism cases are due to recessive mutations in genes
Time of Update: 2021-02-25
, June 26 (Xinhua) -- A large-scale international study has found that recessive mutations in genes cause autism more commonly than previously thought, with 3 to 5 percent of cases linked.
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Pfizer has invested $500 million in gene therapy
Time of Update: 2021-02-25
high-tech manufacturing environment and is part of our overall plan to invest about $5 billion in U.S. capital projects over the next few years. ”（cyy123.com）
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Qinghai explores and explores the immune gene of Tibetan sheep against disease
Time of Update: 2021-02-25
xinhua News Agency, Xining, July 6 (Reporter Bai Ma Zhongtao) reporters from Qinghai Province Science and Technology Department learned that recently, a commitment to solve the problem of Tibetan sheep breeding epidemic basic scientific
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Gene therapy pioneer James Wilson's team has found new ways to reduce the toxicity of gene therapy
Time of Update: 2021-02-24
However, experiments in non-human primates (NHP) have found that gene therapy targeting the central nervous system can be toxic in the back root nerve section (DRGs), leading to the development of ataxia.
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Beware of gene therapy side effects "angel syndrome" clinical trials have been called off
Time of Update: 2021-02-24
experienced the same adverse reactions after receiving the highest dose. these symptoms appear one to four weeks after the participants were last given the drug. two of the patients had lower limbs that were unable to walk or carry weight
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HKEx gene sequencing the first shares of Beikang Medical listed
Time of Update: 2021-02-24
The listing will be the first gene sequencing stock on the Hong Kong Stock Exchange, opening the door to the large-scale industrialization of three generations of IVF kits.
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Development of Bacterial Species-Specific DNA Probes Based on Ribosomal RNA Genes Using PCR
Time of Update: 2021-02-24
to develop DNA probes for specific bacteria that include the use of genes for antigenic determinants and virulence factors, randomly cloned DNA fragments, high copy number sequences including insertion elements, and ribosomal RNA (rRNA) genes ( 1
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JAMA Oncol: 22 Gene Genome Classifiers predict the risk of distant metastasis after prostate cancer!
Time of Update: 2021-02-24
in multivariate analysis, GC and DM (risk ratio 1.17; 95% CI 1.05-1.32; P-0.22; P-0.2) were calibrated by age, race/ethnicity, Gleason score, T-phase, cut-off state, prostate-specific antigen and treatment.
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Lilly has teamed up with Precision for gene therapy for Duchy muscular dystrophy
Time of Update: 2021-02-24
/>ARCUS® is a highly specific and versatile genomic editing technology platform discovered and developed by Scientists at Precision, designed with treatment safety, delivery efficiency and effectiveness control in account. it uses a specific
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Characterization of Carotenogenesis Genes in the Cyanobacterium Anabaena sp. PCC 7120
Time of Update: 2021-02-24
PCC 7120), we have produced gene-disruption mutants lacking selected proposed carotenoid biosynthetic enzymes.
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Nat Commun: The absence of BCMA's double allegiant gene in patients with multiple myeloma causes the development of drug resistance in CAR-T therapy
Time of Update: 2021-02-24
Targeted BCMA (B-cell mature antigen) inlay antigen-subject (CAR) T-cell therapy has now shown far-reaching and long-lasting response effects in recurring refractic multiple myeloma (MM), the initial Phase I/II study showed that the therapy has
