-
The latest research scientist reveals the 3D of the special complex responsible for gene expression in cells...
Time of Update: 2021-05-03
Recently, in a research report titled "Structure of the human Mediator-bound transcription pre-initiation complex" published in the international journal Science, scientists from Northwestern University and other institutions have observed responsibility in human cells for the first time through research.
-
Talking about: Sulfonate Drugs & Sulfonate Gene Toxicity
Time of Update: 2021-05-02
On June 6, 2007, the European EMA discovered that some batches of anti-AIDS drug Viracept, that is, nelfinavir mesylate containing high doses of genotoxic impurity ~ ethyl methanesulfonate, decided to recall Roche Pharmaceuticals Viracept.
-
$900 million to help develop CRISPR gene editing therapy Vertex renews cooperation
Time of Update: 2021-05-02
CTX001 is a gene editing therapy based on CRISPR/Cas9 technology and is being developed to treat sickle cell anemia (SCD) and transfusion-dependent β-thalassemia syndrome (TDT).
-
Latest research scientists reveal the 3D structure of a special complex responsible for gene expression in cells
Time of Update: 2021-04-28
Recently, in a research report titled "Structure of the human Mediator-bound transcription pre-initiation complex" published in the international journal Science, scientists from Northwestern University and other institutions have observed responsibility in human cells for the first time through research.
-
The detection rate of the new coronavirus mutation gene E484K in six Brazilian states exceeds 50%
Time of Update: 2021-04-28
As of 20:00 local time on March 4th, according to data released by the Brazilian Ministry of Health, Brazil has a total of 10,793,732 confirmed cases of new coronary pneumonia, an increase
-
ANXA2-"Chinese Diabetic Retinopathy" Potential Susceptibility Gene | ENDO2021
Time of Update: 2021-04-28
Research results In the discovery stage, the strongest association with STDR was detected on an intron variant of ANXA2.
-
Nat Commun: Gene therapy can be effective for decades
Time of Update: 2021-04-28
html">Cellular benefits of gene therapy seen decades after treatmentOriginal source: Natalia Izotova et al, Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans, Nature Communications (2021).
-
Sci Immunol: Identify special genes that play a key role in the differentiation of natural killer cells!
Time of Update: 2021-04-28
role in the differentiation of natural killer cells. In the article, the researchers describe how the function of this gene involves the transcription and epigenetic profile of natural killer cells (NK cells). In another
-
Cell points out that this gene affects iron levels
Time of Update: 2021-04-28
The researchers found that the dysregulation of macrophage-specific hepcidin is a key factor in the age-related iron overload of GOF PIEZO1 mice.
-
Chen Gong’s team at Jinan University developed anti-cancer gene therapy: directly transforming gliomas into neurons
Time of Update: 2021-04-27
published a series of research results, which proved that after overexpression of neuronal transcription factors such as NeuroD1 and Dlx2, astrocytes in the brain can be directly transformed into functional neurons in situ.
-
The BMI1 gene prevents Alzheimer’s disease by inhibiting the production of four-stranded DNA in neurons
Time of Update: 2021-04-27
In this Nature Communications paper, the research team found that G-quadruplex structures accumulate in the brain neurons of Alzheimer's patients, but not in the brains of healthy elderly people.
-
Talking about: Sulfonate Drugs & Sulfonate Gene Toxicity
Time of Update: 2021-04-24
infection; it was developed by Agouron, approved by the US FDA in 1997, approved by the European EMA in 1998, and approved by the Japanese PMDA in 1998 , Jointly sold by Agouron and ViiV Healthcare in the US market under the trade name Viracept®.
-
Immunity | Connecting stem cell fate and gene expression through the "time machine"
Time of Update: 2021-04-23
>It is also possible to use expressible DNA barcodes to simultaneously label multiple hematopoietic stem cells and isolate sister cells to increase throughput [4]. Tian Luyi, Sara Tomei, Jaring Schreuder
-
Sub-Journal of "Nature": There are "zombie genes" in the brain. People die, but they live
Time of Update: 2021-04-23
Selective time-dependent changes in human brain activity and cell-specific gene expression after death Next, the researchers performed histological observations on brain tissue samples within 24 hours of brain death and discovered three types of genes.
-
Survival from a dead end: advanced triple-negative breast cancer discovered driver gene mutations, targeted therapy to relieve the condition
Time of Update: 2021-04-23
Verofenib is a targeted drug for the BRAF gene V600E mutation site, but it has not been indicated for triple-negative breast cancer.
-
Science contention | The core position of the biological clock "conductor" BMAL1 gene shakes?
Time of Update: 2021-04-23
>Circadian clocks, as an almost ubiquitous feature in eukaryotic life, are a hot topic of research and discussion by scientists (see "Collector's Edition" Science Review | Current Status and Prospects of Circadian Clocks, Cancer and Chemotherapy
-
Chinese scientists identify susceptibility genes for schizophrenia in East Asian population
Time of Update: 2021-04-22
