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Bayer has released the latest clinical data for the treatment of TRK fusion cancer with the targeted drug Vitrakvi
Time of Update: 2021-03-03
/> Vitrakvi is an oral TRK inhibitor specifically designed to treat children and adults with late-stage or metastasis solid tumors that have neurotrophic tyrosine-like kinase (NTRK) gene fusion in tumors. Currently, Vitrakvi has been
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Nature sub-journal interpretation! Spontaneous cell fusion may amplify genetic diversity in tumors!
Time of Update: 2021-03-03
locations, giving these mixed cancer cells a more direct and specific advantage; Studies have shown that fusion between non-cancerous cells induced by the virus may lead to cancer initiation events, however, because spontaneous fusion is relatively
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FDA approves RET inhibitor Gawreto to treat RET fusion positive lung cancer
Time of Update: 2021-03-02
therapy. In particular, up to 50% of RET fusion-positive NSCLC patients may have tumor brain metastasis, and in patients with baseline brain metastasis, Retevmo showed strong efficacy, with intracranial remission (CNS-ORR) up to 91% (n-10/11). (Bio Valley Bioon .com)
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The first Fusion Science Centre was launched in the UK
Time of Update: 2021-02-26
Researchers are using innovative methods that will enable the center's team to work together in new ways to accelerate scientific discovery and innovation in cancer patients and to create new treatments and technologies.
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fusion Huiju
Time of Update: 2021-02-25
clone monkey, Chinese Academy of Sciences Brain Science and Intelligent Technology Innovation Center for Illustration Drink milk powder in the nursery box, play with rag dolls, play with each other ... Remember "China-China
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Viral Glycoprotein-Mediated Cell Fusion Assays Using Vaccinia Virus Vectors
Time of Update: 2021-02-18
This chapter will detail the methods of the vaccinia virus-based reporter-gene fusion assay and how it may be used to characterize the fusion mediated by the BSL-4-classified Hendra and Nipah viruses.
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Intracellular Expression of Recombinant Antibody Fluorescent Protein Fusions for Localization of Target Antigens in Schizosaccharomyces pombe
Time of Update: 2021-02-14
We show here that recombinant antibody fluorescent protein fusions can be used to monitor the localization of intracellular antigens in fixed or living cells.
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Pemigatinib treats advanced bile tube cancer with FGFR2 fusion or rearmissing, chMP said positively
Time of Update: 2021-02-04
if approved, pemigatinib will be the first targeted treatment in the EU for patients with non-removable localized advanced or metastatic bile tube cancer who are fused or rearmed with FGFR2.
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34 Expression of scFvs and scFv Fusion Proteins in Eukaryotic Cells
Time of Update: 2021-01-25
scFvs have considerable therapeutic potential against antigens (Ags) involved in disease processes ( 1,2) , either as proteins synthesized ex vivo for passive administration, or introduced by gene therapy
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Gene Fusions for the Directed Modification of the Carotenoid Biosynthesis Pathway in Mucor circinelloides
Time of Update: 2021-01-25
In this chapter we describe part of our efforts to construct active gene fusions which could advance in the diversification of carotenoid production by this fungus.
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JCO Precision Oncol: NTRK fusion is more common in childhood tumors than expected
Time of Update: 2021-01-23
1,347 consecutive child tumors in 1,217 patients who performed tumor genome analysis using custom-designed DNA and RNA next-generation sequencing panels. researchers found NTRK fusion in 29 tumors in 27 patients, with a positive rate of 2.22
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Save people across provinces! "Dr. Academician"'s Yangtze River Delta medical fusion tour
Time of Update: 2021-01-22
came to the First Hospital affiliated with the University of Science and Technology of China (Anhui Provincial Hospital) as . Because he still has a job in Shanghai, he runs in Shanghai and Anhui, always in a hurry. the first night more
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Fusion with Fluorescent Proteins for Subcellular Localization of Enzymes Involved in Plant Alkaloid Biosynthesis
Time of Update: 2021-01-19
This chapter describes the application of this methodology to an enzyme involved in indole alkaloid biosynthesis, with general considerations on the development of the approach.
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Subcellular Localization of Transiently Expressed Fluorescent Fusion Proteins
Time of Update: 2021-01-18
It will describe some of the technology available for visualizing protein localizations, and some of the experimental approaches for optimizing and confirming localizations generated by particle bombardment in onion epidermal cells, the most commonly used experimental system.
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FDA grants Zenotuzumab 'fast track qualification' to treat NRG1 gene fusion tumors
Time of Update: 2021-01-16
Merus is currently recruiting patients for Phase I/II clinical trials aimed at evaluating the effectiveness of Zenocutuzumab's single-drug treatment of pancreatic cancer and other solid tumors that are fusion of the NRG1 gene.
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Creative Photography: The Fusion of Science and Art (Picture)
Time of Update: 2021-01-08
a gas mask and wears protective clothing. Just when you think she might have exhausted her colors and ideas, she's going to launch a new gorgeous piece, "I feel like there's an infinite possibility." 。
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A Tripartite Fusion System for the Selection of Protein Variants with Increased Stability In Vivo
Time of Update: 2021-01-05
Mutations that stabilize the protein of interest can easily be identifiedon the basis of their increased antibiotic resistance compared to cells expressing the unmutated tripartite fusion.
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The new fusion protein therapy is expected to treat clotting disorders
Time of Update: 2021-01-05
researchers have developed an experimental fusion protein called BIVV001, which has not been shown to stop haemophilia patients from bleeding in a large-scale clinical trial, but it can prolong the clotting factor, much to the excitement of some researchers.
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Insertion of Promoter Region::luxCDABE Fusions into the Escherichia coil Chromosome
Time of Update: 2021-01-02
Transcriptional reporter systems have been extensively used to measure gene expression.
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Mercadon acquires Oncolmmune: Obtains the first recombination fusion protein CD24Fc, Phase 3 clinical treatment COVID-19 has significant efficacy!
Time of Update: 2020-12-30
, Oncolmmune recently published positive results for the midterm efficacy analysis of COVID-19 Phase 3 clinical studies in CD24Fc, showing that CD24Fc has significant efficacy in treating patients with severe and critical COVID-19.
