-
Alzheimer&Dementia: Adherence to a healthy lifestyle can reverse the impact of genetic risk factors on Alzheimer's disease
Time of Update: 2022-05-25
Using data from the Chicago Health and Aging Project (1993-2012; n = 3874), the researchers defined genetic risk based on the presence or absence of the lipoprotein E (APOE) 𝜀4 allele and used scores on five factors to determine health life> .
-
Four commonly used drugs can reverse Alzheimer's disease in mice
Time of Update: 2021-11-15
"Chemical inspection: detecting the most promising moleculesAfter determining the characteristics of the disease, the scientists used the Chemical Checker, a computational tool developed by the same research team, to discover what is already on the market that can reverse this effect at the cellular level.
-
4 commonly used drugs can reverse symptoms of Alzheimer's disease mouse model
Time of Update: 2021-11-15
Researchers have characterized the comprehensive characteristics of the mouse AD model in the early, middle and late stages at the phenotypic and molecular level, including transcriptomics and proteomics characteristics, and explored the molecular changes related to the onset, progression, and late stages of AD, and Correlate them with cognitive status and Aβ accumulation to study disease dynamics and compare observed changes with healthy aging processes .
-
EbioMedicine: Axitinib may effectively reverse the pathological manifestations of Alzheimer's disease
Time of Update: 2021-11-05
Recently, in a research report titled "Reversing pathology in a preclinical model of Alzheimer's disease by hacking cerebrovascular neoangiogenesis with advanced cancer therapeutics" published in the international journal EbioMedicine, scientists from the University of British Columbia and other institutions found through research that A drug commonly used to treat cancer may help restore memory and cognitive functions in mice that show symptoms of Alzheimer's disease .
-
A cancer-targeted drug can reverse symptoms in Alzheimer's disease mice
Time of Update: 2021-10-09
Mice with Alzheimer's disease received axitinib treatment, the blood vessels and other disease markers in the brain decreased, and also performed very well in learning and memory tests .
-
Cell Journal: This miRNA can reverse Alzheimer's memory loss
Time of Update: 2021-06-18
The study confirmed that adult hippocampal neurogenesis (AHN) is directly affected by the pathology of Alzheimer's disease (AD) and revealed the potential therapeutic potential of increasing miR-132 levels in neurodegenerative diseases .
-
Innovative therapy to reverse the symptoms of Alzheimer's disease in animals stimulates cells to "clean up garbage"...
Time of Update: 2021-05-10
On April 22, researchers at the Albert Einstein College of Medicine in New York, the United States, announced the design of an experimental drug designed to stimulate a special cell "garbage cleanup" mechanism, which can be used in animal models.
-
Frontier | Innovative therapy reverses the symptoms of Alzheimer's disease in animals and stimulates the ability of cells to "clean up garbage"
Time of Update: 2021-05-09
The researchers further observed the single-cell RNA sequencing data of brain neurons in patients with Alzheimer's disease and control healthy individuals.
-
Innovative therapy reverses the symptoms of Alzheimer's disease in animals and stimulates cells to "clean up garbage"
Time of Update: 2021-05-09
"On April 22, researchers at the Albert Einstein College of Medicine in New York, the United States, announced the design of an experimental drug designed to stimulate a special cell "garbage cleanup" mechanism, which can be used in animal models.
-
Cell blockbuster: Enhance neuronal autophagy, clear brain toxic proteins, reverse Alzheimer’s disease, and anti-aging
Time of Update: 2021-05-09
The research team has developed an experimental drug that can clear the tau protein by activating chaperone-mediated autophagy (CMA) in brain neurons and reverse key symptoms in a mouse model of Alzheimer's disease.
-
Cell: Enhance neuronal autophagy, clear brain toxic proteins, reverse Alzheimer's disease, and anti-aging
Time of Update: 2021-05-08
The research team has developed an experimental drug that can clear the tau protein by activating chaperone-mediated autophagy (CMA) in brain neurons and reverse key symptoms in a mouse model of Alzheimer's disease.
-
Nat Commun: Depleting B cells can reverse the progression of Alzheimer's disease
Time of Update: 2021-04-23
Despite the expression of a transgene that promotes AD, the loss of B cells alone is sufficient to reduce the burden of Aβ plaques and disease-related microglia .
Loss of B cells alone is sufficient to reduce the burden of Aβ plaques and disease-related microglia.
-
High risk of inherited Alzheimer's disease, or can it be reversed by "food supplement"?
Time of Update: 2021-03-22
Recently, a study led by Professor Lihui Cai, a neuroscientist at the Massachusetts Institute of Technology (MIT) and a collaborator, gave us a new understanding of the role of the APOE4 gene in the development of Alzheimer's disease.
-
Acta Neuropathol: Gene new therapy beats you to reverse Alzheimer's-related memory loss.
Time of Update: 2020-08-25
July 29 A study by the brothers, Arne Ittner and Professor Lars Ittner of the Dementia Research Centre at Macquarie University in Sydney, Australia, showed that the active form of tau kinase p38 to neurons could improve the cognition of mice with AD models that already had significant memory impairments.
-
Now reverse? Cell revisits the role of important pathological proteins in Alzheimer's disease.
Time of Update: 2020-08-02
the results of this study (Photo Source: References) these results clearly show that amyloid protein deposition is not a simple "pathogenia" but rather a series of genetic changes that may be involved in the onset of neurodegenerative diseases.
the authors point out that we should further study the effects of amyloid protein deposits on Alzheimer's disease.