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New way to shrink cancerous tumors through human immune cells
Time of Update: 2022-05-17
"Knockout of PERK inhibits downstream metabolic signaling in tumor macrophages, resulting in more T cells to fight cancer cells," Huang said .
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Enhance the killing effect of ionizing radiation on tumor cells
Time of Update: 2022-05-17
When T cells are simultaneously exposed to X-rays, the expected stimulating effect on the immune system is directly triggered, the researchers report in the Journal of General Physiology .
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Cell paper reveals new family of pore-forming toxins from Enterococcus
Time of Update: 2022-05-17
This article is from the NEJM Journal Watch Review of Pore-Forming Toxins in Enterococcus Species by George Sakoulas, MD Enterococcus β-barrel pore-forming toxins recognize HLA-1 in vitro complex and mediate cytotoxicity .
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Leukemia: Prognosis for early relapse after autologous stem cell transplantation in Hodgkin lymphoma patients has improved in recent years
Time of Update: 2022-05-17
C Cumulative incidence of checkpoint inhibitor (CPI) use according to year of relapse in adult patients relapsed after autologous sct in patients with relapsed/refractory classic HL following first-line therapy .
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Injectable stem cell assembly for cartilage regeneration
Time of Update: 2022-05-17
They established an injectable hybrid inorganic (IHI) nanoscaffold-templated stem cell assembly and applied it to the regeneration of critical-size cartilage defects .
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Intranasal breast milk as stem cell therapy for intraventricular hemorrhage in premature infants: safety, feasibility, and short-term outcomes
Time of Update: 2022-05-17
Gallipoli will present "Intranasal Breast Milk as Stem Cells for Intraventricular Hemorrhage in Preterm Infants: Safety, Feasibility, and Short-Term Outcomes" on Saturday, April 23 at 10:15AM (MDT) .
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Electrocuting Cancer Cells - New "NanoKnife" Technology
Time of Update: 2022-05-17
The technique uses electrical current to destroy cancer cells without harming surrounding healthy tissue and nerves, making it a good option for people with low or intermediate risk prostate cancer .
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"Cell Stem Cell" artificially cultivates self-sustaining muscle cells
Time of Update: 2022-05-17
In a second set of experiments, the researchers transplanted muscle stem cells into genetically engineered mice with mutations in the gene for muscular dystrophy, resulting in Duchenne muscular dystrophy, a mouse and human Muscle wasting disease .
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Cell Stem Cell: Thyroid hormone found to be a missing ingredient in lab-made liver cells
Time of Update: 2022-05-17
However, the researchers found that while the stem cell-derived liver cells produced the right amount of THRB, something prevented it from binding where it should and performing its function .
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Why does Alzheimer's disease kill so many brain cells?
Time of Update: 2022-05-16
But in this study, the scientists found that, affected by Alzheimer's disease, the somatic mutations accumulated in nerve cells in the brains of patients were abnormal in both speed and type .
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Cell sub-journal: 7 months after the new crown, virus residues still exist in feces
Time of Update: 2022-05-16
Med Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infectionThe study showed that even if the virus was no longer detectable in the respiratory tract, 12.
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Nature: New discovery of immune cells
Time of Update: 2022-05-16
Now, researchers at the Sloan Kettering Institute (SKI) report that they have identified a new "soldier" of immune cells in mice that could be a good target for immunotherapy .
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COVID-19 can directly infect and damage human kidney cells
Time of Update: 2022-05-16
"To test their podocyte model with the real SARS-CoV-2 virus, Musah and Kalejaiye collaborated with Maria Blasi, an assistant professor of medicine at Duke University and a researcher at the Duke Human Vaccine Institute .
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by promoting monocyte-derived dendritic cells through CXCL10 in cancer
Time of Update: 2022-05-15
On April 23, 2022, Researcher Zhu Di of Fudan University published a paper titled "RORγt agonist enhances anti-PD-1 therapy by promoting monocyte" in the Journal of Experimental & Clinical Cancer Research (IF=11.
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Jiaotong University joined hands to map the proteogenomic features of Chinese renal clear cell carcinoma
Time of Update: 2022-05-15
In 2019, the American Clinical Proteomics Tumor Analysis Consortium (CPTAC) published the proteogenomic characteristics of 103 clear cell renal cancer patients, which provided the basis for precise treatment of renal cancer in European and American countries .
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Nature: Newly discovered T cells are expected to become a new force in immunotherapy
Time of Update: 2022-05-15
A recently discovered type of immune cell could be a new force in immunotherapy, researchers at Memorial Sloan Kettering Cancer Center report .
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Science: Cancer cells repair their own membranes after being attacked by T cells
Time of Update: 2022-05-14
In their paper published in the journal Science, the team describes how they used high-resolution imaging to learn more about what happens when T cells, or cytotoxic T lymphocytes (CTLs), attack cancer cells .
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mesenchymal stromal cells in the treatment of systemic sclerosis
Time of Update: 2022-05-14
This study was designed to test the safety and feasibility of a single intravenous injection of familial allogeneic bone marrow-derived mesenchymal stromal cells in the treatment of severe diffuse systemic sclerosis .
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A new type of cell death has been discovered!
Time of Update: 2022-05-14
New research challenges this hypothesis, providing evidence for a second type of programmed cell death that may target the gut .
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Stem Cell Res Ther: Mesenchymal Stem Cells or Effective Therapy for Systemic Sclerosis
Time of Update: 2022-05-14
Taken together, the results of this study show that mesenchymal stem cell therapy can improve skin thickening, lung function, and mouth opening in patients with SSc, and relieve finger ulcers and pain without serious adverse events .
