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    thyroid hormone homeostasis

    View news and stories of thyroid hormone homeostasis. Echemi provides huge amount of thyroid hormone homeostasis information to support you.
    • Nature sub-journal: Ying Hao's team reveals a new mechanism by which thyroid hormones regulate blood glucose homeostasis

      Time of Update: 2022-11-05
      Activating the hepatic thyroid hormone signaling pathway has the effect of insulin secretion and lowering blood sugar, the mode of action is to change the composition of bile acids by inhibiting the expression of CYP8B1, increase the level of non-12α-hydroxybile acids with FXR antagonism, thereby increasing the production of GLP-1 by inhibiting the intestinal FXR signaling pathway, revealing the feasibility of TRβ agonists targeting the liver in the future for the treatment of type 2 diabetes.

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