-
How toxic aggregates in prion diseases form and kill brain cells
Time of Update: 2022-01-09
How these aggregates form and kill brain cells is still not fully understood, but a new study by scientists at Scripps Research shows that these aggregates can destroy The axon of a neuron kills the neuron.
-
How brain cells die in prion diseases
Time of Update: 2022-01-07
The researchers also discovered a key protein complex that is responsible for guiding PrP to axons and causing aggregation associated with axon swelling .
The researchers found in their experiments that the mutant PrP produced in somatic cells is also largely encapsulated in vesicles, which move to axons along railroads called microtubules .
-
Molecular Cell: The first atomic-level imaging of deadly prions
Time of Update: 2021-09-03
Source: Case Western Reserve University/National Institute of Health and DevelopmentThe highest-resolution imaging of infectious prions ever provides the first atomic-level data on how these abnormal proteins assemble in humans and animals to cause deadly neurodegenerative diseases, and how they may become new treatments Goal .
-
Neuron & cell Rep: prion like special protein or
Time of Update: 2015-07-13
July 6, 2015 / BIOON / -- recently published in the international journal Neuron and cell In two research papers on reports, researchers from Columbia University Medical Center revealed the secret of
