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"Nature" heavy: Chinese scientists crack the mechanism of action of metformin

 Time of Update: 2022-05-23

▲Metformin binds to PEN2 to activate AMPK (Image source: Reference [1])Next, the research team revealed the pathway by which metformin works based on this newly discovered target .
Xiangxi Market Supervision Bureau launches special rectification action for special food

 Time of Update: 2022-05-22

>such as "keeping the bottom line, checking hidden dangers, and ensuring safety" , and investigated and dealt with more than 50 potential safety hazards of
"Beijing Plastic Pollution Control Action Plan 2022 Work Points" issued

 Time of Update: 2022-05-20

(The Municipal Bureau of Commerce, the Municipal Market Supervision Bureau, the district governments, and the Management Committee of Beijing Economic and Technological Development Zone shall be responsible according to the division of responsibilities; continue to advance) 　　3.
Green transition in Asia in action

 Time of Update: 2022-05-18

The "Report" proposes that, as an important global growth engine, many Asian countries have made carbon commitments in 2021, and governments, businesses and civil society are all taking active actions .
Nature: Widespread brain receptor hides surprising mechanism of action

 Time of Update: 2022-05-17

Rather than a direct step-by-step transition, Sobolevsky and his colleagues found that the glutamate molecule must first bind to one of two specific subunits of the receptor before it can bind to the other two .
The EU's first migraine drug with both curative/preventive action!

 Time of Update: 2022-05-16

States, with a total transaction value of up to $1. 24 billion . >This time, rimegepant was finally approved for marketing in Europe, following the approval recommendation
The EU's first migraine drug with both curative/preventive action!

 Time of Update: 2022-05-15

/> The final approval of rimegepant in Europe follows the approval recommendations made by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) in February.
Cell: Mechanism of action of GPCRs

 Time of Update: 2022-05-12

"In our study, we used an approach that allowed us to explore, in unprecedented detail, how drug-stimulated GPCRs activate β-arrestin, a protein that both terminates some signals and mediates others ” said Wesley B.
JCI: Shen Zhanlong's team from Peking University People's Hospital reveals the mechanism of action

 Time of Update: 2022-05-09

screen patients who benefit from PD-L1 inhibitor therapy, from single-cell precision Revealed a new mechanism of immunotherapy targeting TAM cells and dendritic cells (DC), and discovered a new mechanism of ubiquitination regulation with better
Ningxia launches chemical industry quality management system certification promotion action

 Time of Update: 2022-05-08

Department has organized and carried out the quality management system certification and improvement actions of small and micro enterprises in the region around the "nine key industries" of the autonomous region, and enhanced the quality management
"Industrial Internet + Safe Production" Action Plan (2021-2023) announced

 Time of Update: 2022-05-04

> Safe Production "Action Plan (2021-2023 years ) . ">
Three major goals and eight major actions The Chinese Academy of Sciences released a scientific and technological support "dual carbon" strategic action plan

 Time of Update: 2022-05-01

>The action plan states that the Chinese Academy of Sciences will deploy eight major actions in scientific and technological strategic research, basic frontier cross-innovation, breakthroughs in key core technologies, comprehensive demonstration of new
10 new national ecological and environmental standards are newly released to fully promote the implementation of the "double carbon" action

 Time of Update: 2022-05-01

Carboxylic Acid Compounds in Ambient Air by Gas Chromatography-Mass Spectrometry" (HJ 1220-2021) 　　This standard is also released for the first time, and can support the implementation of pollutant
Chongqing issues an action plan for the development of the chemical industry

 Time of Update: 2022-05-01

>>>　　In addition, the number of chemical enterprises above designated size that have established R&D institutions has reached 160, an increase of 70 from the end of the "13th Five-Year Plan" period
The "World Obesity Day" summit forum of the branch released "15 Expert Suggestions on Obesity Prevention and Control Actions"

 Time of Update: 2022-04-27

of professional institutions, and food producers and operators, so as to improve the public's awareness of obesity hazards, influencing factors and prevention measures . >
The General Administration launched a special rectification action for the inspection and testing market in 6 major areas

 Time of Update: 2022-04-26

>　　(1) Carry out special rectification actions in six major areas . According to the principle of territorial jurisdiction, local market supervision departments should concentrate
Food saving and loss reduction focus on action

 Time of Update: 2022-04-26

in terms of grain storage, preservation and quality, pest and mildew control, and key technologies for loss and consumption reduction through technologies such as controlled atmosphere grain storage, low-temperature and quasi-low-temperature grain
The country takes action, pig companies expand the brakes, and the "positive ...

 Time of Update: 2022-04-25

>As the "pig leader", Muyuan shares performed most prominently when the industry was at a low point. The recent complete cost of breeding is about 15 yuan/kg, including non-cash costs such as depreciation and amortization of about 2
Chongqing carries out special rectification actions for drug safety from "strict"

 Time of Update: 2022-04-24

and filing process, cracking down on "black dens" for producing and selling counterfeit goods, and medicines. Special rectification of production links, drug business and use links, medical device production, business and use links, cosmetics
Two-faced needles practice national unity with practical actions

 Time of Update: 2022-04-23

2018 Liangmianzhen National Unity and Progress Symposium Rooted in the fertile soil of the nation to build century-old shopLiangmianzhen Company is located in Liuzhou City, a multi-ethnic gathering place and an important industrial city in Guangxi .

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