CELL: Reactivation of CaMKII can protect optic nerve cells to prevent vision loss from glaucoma
Time of Update: 2021-07-27
Similarly, in glaucoma models based on elevated intraocular pressure or genetic defects, gene therapy to increase CaMKII activity proved to have a protective effect on retinal ganglion cells .
Molecular Cell: Special microscope helps understand new forces shaping the genome
Time of Update: 2021-07-27
traditional microscopes, and combined with advanced imaging analysis techniques, researchers are able to identify chromatin loops, as well as the internal polymer that holds the structure together like a paper clip, in an intact cell . >###>
Cell Sub-Journal: This molecule makes the adult hippocampus nerve regeneration firstly strong and then weak, and finally "lying down"
Time of Update: 2021-06-30
This indicates that during the transition from adolescence to adulthood, the differentiation of neural stem cells proliferating in the hippocampus gradually decreases, gaining the ability to restore rest and maintaining the stability of the number of neural stem cells .
Dev Cell | Sheng Zuhang's team reveals the neurodegenerative pathogenic mechanism of nerve cell
Time of Update: 2021-04-23
garbage in cells, and are an important part of maintaining cell homeostasis. NPC1 gene defects can cause lipid transport barriers in cells, leading to the deposition of large amounts of free cholesterol
Study on the influence of the structure of the inner surface groove of polymer nerve catheters on the growth of nerve cells
Time of Update: 2021-03-23
Adding a groove structure on the inner surface of the catheter can effectively guide the growth of nerve cells, thereby promoting the regeneration and functional repair of damaged nerves.
Immunity | A New Mechanism of Neural-Immune System Interaction: IL6 from Enteric Nerve Cells Regulates Regulatory T Cell Levels
Time of Update: 2021-03-22
Next, the authors investigate whether these symbiotic bacteria affect the level of regulatory T cells by affecting the enteric nervous system.
Neuron| Weak anti-inflammatory, strong pro-inflammatory, the key is this protein. Scientists reveal new anti-inflammatory cells for nerve pain
Time of Update: 2021-03-22
This indicates that the number of anti-inflammatory Mrc1+ meningeal macrophages is reduced in the neuropathic pain model.
Choline Labeling and TNF Treatment of HL-60 Cells
Time of Update: 2021-03-07
3) Resuspend final pellet in an appropriate volume of prewarmed serum free media and supplement with ITS (4 ml/L should yield 5 mg/L insulin and 5 mg/L transferrin).
On-Column Labeling Reaction for Analysis of Protein Contents of a Single Cell Using Capillary Electrophoresis With Laser-Induced Fluorescence Detection
Time of Update: 2021-03-05
A custom-made CE instrument with laser-induced fluorescence (LIF) detection, used for the analyses, is described.
Science: The erythrative factor Oct4 is closely related to the expansion of the differentiation potential of cranial nerve cells
Time of Update: 2021-02-27
February 10, 2021 // --- Cell differentiation is often described as a one-way process through a series of genealogical restriction events, and as the embryo develops, the cell's differentiation potential becomes smaller and smaller, a concept
Phosphoinositidase C Activation Assay I: Cell Labeling, Stimulation, and Recovery of Cellular [3H]Phosphoinositides and [3H]Phosphoinositols
Time of Update: 2021-02-24
For phosphoinositols, abbreviations are in the form Ins(x,y,z )Pn , wherex, y , andz refer to the positions of the phosphate groups on the myo-inositol ring andn refers to the total number of phosphates.
Caffeine protects nerve cells in the brain, and caffeine concentrations in the blood can diagnose Parkinson's
Time of Update: 2021-02-18
Japanese media reported that Japan's Shun paradise university and other teams in this month's 3 issue of the American journal science published research results, found a way to investigate the concentration of caffeine in the blood
Solve the mystery of cancer metastasis CRISPR technology gives each cancer cell a special "label"
Time of Update: 2021-02-11
Using single-cell RNA sequencing, the researchers compared gene expression maps of cancer cells with different metastasis potentials.
J Exp Med: SARS-CoV-2 can infect nerve cells and cause tissue damage
Time of Update: 2021-01-29
A recent study by a team of scientists provides evidence that SARS-CoV-2 can directly infect cells in the central nervous system (CNS) and cause tissue damage.
Cell: An automated electron microscope platform has been developed to reconstruct the neural circuit map at high resolution
Time of Update: 2021-01-27
the problem with electron microscopes is that while it provides such a high image resolution, it has been difficult to study the entire neural circuit," Lee said.
Nature: New discovery! Pain nerves may help regulate the mobilization of the body's hematopoietic stem cells!
Time of Update: 2021-01-20
JANUARY 4, 2021 // -- In a recent study published in the international journal Nature, scientists from the Albert Einstein College of Medicine and others found that pain nerves in the body's bone marrow may help regulate the mobilization
The Role of Inositol and the Principles of Labelling, Extraction, and Analysis of Inositides in Mammalian Cells
Time of Update: 2021-01-06
In this chapter, we establish a broad foundation for the rest of the book by covering some important principles of inositide methodologies.
Single-Step Conjugation of Antibodies to Quantum Dots for Labeling Cell Surface Receptors in Mammalian Cells
Time of Update: 2021-01-05
We describe herein methods that allow conjugation of antibodies to QDs in a single step without the formation of side products.
Application of Microscopic Methods for the Detection of Cell Attachment to Polymers
Time of Update: 2021-01-04
However, many of the protocols described can be modified easily for use with TEM and SEM visualization.
Methods for the Study of Nerve Cell Migration and Patterning
Time of Update: 2021-01-02
Growth cone response to topographical features ( 3 ) or other three-dimensional environments are beyond the scope of this chapter.